A database of genes that, when somatically altered in cancer, are directly linked to a clinical action. TARGET genes may be predictive of response or resistance to a therapy, prognostic, and/or diagnostic.
The Library of Integrated Cellular Signatures (LINCS) is an NIH program which funds the generation of perturbational profiles across multiple cell and perturbation types, as well as read-outs, at a massive scale. Coupled with analytical tools, the vision is to, someday, make it possible for researchers to simply "look up" any cellular response in...
Clustering of Mutations in Protein Structures
