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New technique enables SHERLOCK to detect a virus directly in bodily fluids, eliminating a step that required lab equipment and expanding the platform’s potential to quickly and cheaply track pathogens such as Ebola, Zika, and Lassa fever anywhere in the world

A strip of paper can now indicate presence of pathogens, tumor DNA, or any genetic signature of interest. 100-fold greater sensitivity, the ability to detect multiple targets at once, and other new features further enhance SHERLOCK's power for detecting genetic signatures.

Analysis of the largest collection of Zika genomes to date reveals the trajectory and evolution of the virus as it spread throughout the Americas, with implications for future surveillance efforts.

In the search for a defining feature of the Escherichia coli that cause urinary tract infections, comparative transcriptomics and infection models show that infection depends on both the host environment and gene expression levels in the bacteria.

After screening a library of over 100,000 small molecules, researchers from the Ó³»­´«Ã½ of MIT and Harvard have identified compounds that act on a novel target in the malaria parasite, Plasmodium falciparum. resulted in the publication of a paper (available online September 7 inNature] and an open, data-rich resource for the malaria research community called the(MTRP).