MIT Chemistry and the ӳý host monthly seminars in chemical biology with the intent to hear from the thought-leaders and bring together chemical biologists from both academia and industry in the Boston/Cambridge area.
2025-2026 Speakers
05/18/2026
Discovery and Engineering of New Enzymes for Biocatalysis
Michelle Chang Princeton University
04/27/2026
Developing and Harnessing Stem Cell-Derived Models to Uncover the Genetic Drivers of Multi-Organ Functional Anomalies
Samira Musah Duke University
04/13/2026
Systems Chemical Biology Approach to Antibiotic Discovery
Deb Hung ӳý of MIT and Harvard
11/03/2025
Covalent drug discovery: from serendipity to clinical trials
Jack Taunton UCSF
2024-2025 Speakers
05/12/2025
Structural plasticity in alphavirus interactions with cellular receptors []
Jonathan Abraham Harvard Medical School
04/28/2025
Directed and Random Walks in Chemical Space []
Brian Shoichet UCSF
03/03/2025
Molecular Glues - from Protein Degradation to Transcription Factor Reprogramming []
Nathanael Gray Stanford University
02/24/2025
Replicating RNA with RNA []
Phil Holliger MRC Laboratory of Molecular Biology
02/10/2025
Genome Mining for New Natural Products []
Wilfred van der Donk University of Illinois Urbana-Champaign
11/04/2024
Eavesdropping on the Gut Microbiome []
Jim Wells UCSF
10/07/2024
Disorder Rules: Transcription Factors []
H. Jane Dyson Scripps Research Institute
09/23/2024
Eavesdropping on the Gut Microbiome
Jon Clardy Harvard Medical School
2023-2024 Speakers
05/20/2024
Decoding Glycosaminoglycans and Their Roles in Neuroplasticity
Linda Hsieh-Wilson Caltech
04/29/2024
GPCR to channel communication in a membrane signaling pathway
Rod MacKinnon Rockefeller University
04/22/2024
Overcoming the Undruggable Nature of the Most Common Human Oncogene, K-Ras
Kevan Shokat UCSF
04/08/2024
Molecular origami: Understanding how proteins fold and misfold in living cells
Judith Frydman Stanford University
03/25/2024
Deciphering the mechanisms of lipid trafficking in bacteria
Laura Dassama Stanford University
02/05/2024
Recording the Physiological History of Cells with Chemical Labeling
Kai Johnsson Max Planck Institute
01/29/2024
Activity-based proteomics – protein and ligand discovery on a global scale
Ben Cravatt Scripps Research Institute
01/08/2024
Two medicines that have saved at least 100 million lives
Ed Scolnick ӳý
11/06/2023
Biological and technological frontiers for single-cell proteomics []
Nikolai Slavov Northeastern University
10/02/2023
Making it stick: How to engineer selective covalent ligands for diverse applications in biology []
Matt Bogyo Stanford University
05/08/2023
Chemical Biology of extracellular cGAMP signaling in health and disease
Lingyin Li Stanford University
04/24/2023
Multum in parvo—The mechanism of a protein antibiotic []
Bill Clemons California Institute of Technology
04/03/2023
A radical solution for C(sp3)—C(sp3) bond formation during the biosynthesis of macrocyclic membrane lipids []
Squire Booker Pennsylvania State University
03/06/2023
Reprogramming the Genetic Code
Jason Chin MRC Laboratory of Molecular Biology
02/27/2023
The development of chemical probes of histone “reader” subunits of chromatin remodeling complexes
Emily Dykhuizen Purdue University
02/06/2023
Pharmacological Adaptation of Proteostasis to Ameliorate Aging-associated Degenerative Diseases []
Jeffrey Kelly Scripps Research Institute
01/30/2023
RNA modification in gene expression regulation []
Chuan He The University of Chicago; HHMI
2019-2022 Speakers
11/21/2022
Biomolecular condensates: new insights into regulation and dysregulation of cellular compartments []
Richard Young Whitehead Institute; MIT
10/24/2022
Base Editing and Prime Editing: Precise Chemistry on the Genome without Double—Strand DNA Breaks []
David Liu ӳý; Harvard University; HHMI
09/19/2022
Exploring protein-glycan interactions in immunity []
Laura Kiessling MIT
02/24/2020
Lipid and light-driven tools for cell biology
Carsten Schultz Oregon Health; Science University
12/09/2019
Reimagining Druggability using Chemoproteomic Platforms
Daniel K. Nomura University of California, Berkeley
11/04/2019
Deciphering the Human Microbiota with Chemistry
Emily Balskus Harvard University
10/15/2019
Pseudo Natural Products - Chemical Evolution of Natural Product Structure
Herbert Waldmann Max Planck Institute
09/11/2019
Listening to Probes: Individuals and Populations []