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Publications

Response and Resistance to RAS Inhibition in Cancer.

Ebright RY, Dilly J, Shaw AT, Aguirre AJ. Response and Resistance to RAS Inhibition in Cancer. Cancer discovery. 2025:OF1-OF25. doi:10.1158/2159-8290.CD-25-0349

Ultrasound-activated cilia for biofilm control in indwelling medical devices.

Amado P, Dillinger C, Bahou C, et al. Ultrasound-activated cilia for biofilm control in indwelling medical devices. Proceedings of the National Academy of Sciences of the United States of America. 2025;122(18):e2418938122. doi:10.1073/pnas.2418938122

Efficacy of a novel BCL-xL degrader, DT2216, in preclinical models of JAK2-mutated post-MPN AML.

Wang Z, Skwarska A, Poigaialwar G, et al. Efficacy of a novel BCL-xL degrader, DT2216, in preclinical models of JAK2-mutated post-MPN AML. Blood. 2025;146(3):341-355. doi:10.1182/blood.2024027117

The Somatic Mosaicism across Human Tissues Network.

Coorens THH, Oh JW, Choi YA, et al. The Somatic Mosaicism across Human Tissues Network. Nature. 2025;643(8070):47-59. doi:10.1038/s41586-025-09096-7

FAF2 is a bifunctional regulator of peroxisomal homeostasis and saturated lipid responses.

Kim C, Gabriel KR, Boone D, et al. FAF2 is a bifunctional regulator of peroxisomal homeostasis and saturated lipid responses. Science advances. 2025;11(27):eadu9104. doi:10.1126/sciadv.adu9104

Optogenetics-enabled discovery of integrated stress response modulators.

Wong F, Li A, Omori S, et al. Optogenetics-enabled discovery of integrated stress response modulators. Cell. 2025. doi:10.1016/j.cell.2025.06.024

Multi-omic analysis reveals transkingdom gut dysbiosis in metabolic dysfunction-associated steatotic liver disease.

Kim H, Nelson P, Nzabarushimana E, et al. Multi-omic analysis reveals transkingdom gut dysbiosis in metabolic dysfunction-associated steatotic liver disease. Nature metabolism. 2025. doi:10.1038/s42255-025-01318-6

Loss of CFHR5 function reduces the risk for age-related macular degeneration.

Reeve MP, Loomis S, Nissilä E, et al. Loss of CFHR5 function reduces the risk for age-related macular degeneration. Nature communications. 2025;16(1):5766. doi:10.1038/s41467-025-61193-3

A Molecular Glue Approach to Control the Half-Life of CRISPR-Based Technologies.

Sreekanth V, Jan M, Zhao KT, et al. A Molecular Glue Approach to Control the Half-Life of CRISPR-Based Technologies. Journal of the American Chemical Society. 2025;147(27):23844-23856. doi:10.1021/jacs.5c06230

Ancient DNA reveals the prehistory of the Uralic and Yeniseian peoples.

Zeng TC, Vyazov LA, Kim A, et al. Ancient DNA reveals the prehistory of the Uralic and Yeniseian peoples. Nature. 2025. doi:10.1038/s41586-025-09189-3