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Publications

Response and Resistance to RAS Inhibition in Cancer.

Ebright RY, Dilly J, Shaw AT, Aguirre AJ. Response and Resistance to RAS Inhibition in Cancer. Cancer discovery. 2025:OF1-OF25. doi:10.1158/2159-8290.CD-25-0349

Ultrasound-activated cilia for biofilm control in indwelling medical devices.

Amado P, Dillinger C, Bahou C, et al. Ultrasound-activated cilia for biofilm control in indwelling medical devices. Proceedings of the National Academy of Sciences of the United States of America. 2025;122(18):e2418938122. doi:10.1073/pnas.2418938122

Methyl-CODEC enables simultaneous methylation and duplex sequencing.

Liu R, Darbeheshti F, Walsh L, et al. Methyl-CODEC enables simultaneous methylation and duplex sequencing. Nucleic acids research. 2025;53(10). doi:10.1093/nar/gkaf482

Bacteroides sphingolipids promote anti-inflammatory responses through the mevalonate pathway.

Brown EM, Temple ER, Jeanfavre S, et al. Bacteroides sphingolipids promote anti-inflammatory responses through the mevalonate pathway. Cell host & microbe. 2025;33(6):901-914.e6. doi:10.1016/j.chom.2025.05.007

A versatile information retrieval framework for evaluating profile strength and similarity.

Kalinin AA, Arevalo J, Serrano E, et al. A versatile information retrieval framework for evaluating profile strength and similarity. Nature communications. 2025;16(1):5181. doi:10.1038/s41467-025-60306-2

Realizing the promise of genome-wide association studies for effector gene prediction.

Costanzo MC, Harris LW, Ji Y, McMahon A, Burtt NP, Flannick J. Realizing the promise of genome-wide association studies for effector gene prediction. Nature genetics. 2025. doi:10.1038/s41588-025-02210-5

Glioblastoma-instructed astrocytes suppress tumour-specific T cell immunity.

Akl CF, Andersen BM, Li Z, et al. Glioblastoma-instructed astrocytes suppress tumour-specific T cell immunity. Nature. 2025. doi:10.1038/s41586-025-08997-x

CoQ imbalance drives reverse electron transport to disrupt liver metabolism.

Goncalves RLS, Wang ZB, Riveros JK, et al. CoQ imbalance drives reverse electron transport to disrupt liver metabolism. Nature. 2025. doi:10.1038/s41586-025-09072-1

Proteogenomic analysis of the CALGB 40601 (Alliance) HER2+ breast cancer neoadjuvant trial reveals resistance biomarkers.

Jaehnig EJ, Fernandez-Martinez A, Vashist TD, et al. Proteogenomic analysis of the CALGB 40601 (Alliance) HER2+ breast cancer neoadjuvant trial reveals resistance biomarkers. Cell reports. Medicine. 2025:102154. doi:10.1016/j.xcrm.2025.102154

Association of distinct microbial and metabolic signatures with microscopic colitis.

Chen ASY, Kim H, Nzabarushimana E, et al. Association of distinct microbial and metabolic signatures with microscopic colitis. Nature communications. 2025;16(1):4644. doi:10.1038/s41467-025-59566-9