/ en Wed, 08 Oct 25 15:45:02 -0400 /news/pioneering-effort-patient-partnered-cancer-research-enters-new-phase <span class="field field--name-title field--type-string field--label-hidden">Ó³»­´«Ã½-Novartis Cancer Cell Line Encyclopedia (CCLE)</span> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p> The Cancer Cell Line Encyclopedia (CCLE) project is an effort to conduct a detailed genetic characterization of a large panel of human cancer cell lines. The CCLE provides public access analysis and visualization of DNA copy number, mRNA expression, mutation data and more, for 1000 cancer cell lines. The Cancer Cell Line Encyclopedia (CCLE) project is an effort to conduct a detailed genetic characterization of a large panel of human cancer cell lines. The CCLE provides public access analysis and visualization of DNA copy number, mRNA expression, mutation data and more, for 1000 cancer cell lines.</p> <p> <span style="display:none;">cell line profiling</span></p> </div> <span class="field field--name-uid field--type-entity-reference field--label-hidden"> <span>By bistline@broadinstitute.org</span> </span> <span class="field field--name-created field--type-created field--label-hidden"><time datetime="2012-02-16T15:36:59-05:00" title="Thursday, February 16, 2012 - 15:36" class="datetime">February 16, 2012</time> </span> <div class="field field--name-field-software-link field--type-link field--label-above"> <div class="field__label">Link</div> <div class="field__items"> <div class="field__item"><a href="https://portals.broadinstitute.org/ccle/home">CCLE</a></div> </div> </div> <div class="field field--name-field-taxonomy-topic field--type-entity-reference field--label-above"> <div class="field__label">Topic</div> <div class="field__items"> <div class="field__item">cell lines</div> <div class="field__item">CCLE</div> <div class="field__item">cancer portals</div> <div class="field__item">cancer models</div> <div class="field__item">Cancer</div> <div class="field__item">cancer dependency</div> <div class="field__item">dependency map</div> <div class="field__item">cell line profiling</div> </div> </div> <div class="field field--name-field-broad-tags field--type-entity-reference field--label-above"> <div class="field__label">Ó³»­´«Ã½ tags</div> <div class="field__items"> <div class="field__item"><a href="/broad-tags/cancer-program" hreflang="en">Cancer Program</a></div> <div class="field__item"><a href="/broad-tags/cancer" hreflang="en">Cancer</a></div> </div> </div> Wed, 08 Oct 2025 19:45:02 +0000 leah@broadinstitute.org 5559451 at /news/jason-buenrostro-named-core-institute-member-broad <span class="field field--name-title field--type-string field--label-hidden">Ó³»­´«Ã½-Novartis Cancer Cell Line Encyclopedia (CCLE)</span> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p> The Cancer Cell Line Encyclopedia (CCLE) project is an effort to conduct a detailed genetic characterization of a large panel of human cancer cell lines. The CCLE provides public access analysis and visualization of DNA copy number, mRNA expression, mutation data and more, for 1000 cancer cell lines. The Cancer Cell Line Encyclopedia (CCLE) project is an effort to conduct a detailed genetic characterization of a large panel of human cancer cell lines. The CCLE provides public access analysis and visualization of DNA copy number, mRNA expression, mutation data and more, for 1000 cancer cell lines.</p> <p> <span style="display:none;">cell line profiling</span></p> </div> <span class="field field--name-uid field--type-entity-reference field--label-hidden"> <span>By bistline@broadinstitute.org</span> </span> <span class="field field--name-created field--type-created field--label-hidden"><time datetime="2012-02-16T15:36:59-05:00" title="Thursday, February 16, 2012 - 15:36" class="datetime">February 16, 2012</time> </span> <div class="field field--name-field-software-link field--type-link field--label-above"> <div class="field__label">Link</div> <div class="field__items"> <div class="field__item"><a href="https://portals.broadinstitute.org/ccle/home">CCLE</a></div> </div> </div> <div class="field field--name-field-taxonomy-topic field--type-entity-reference field--label-above"> <div class="field__label">Topic</div> <div class="field__items"> <div class="field__item">cell lines</div> <div class="field__item">CCLE</div> <div class="field__item">cancer portals</div> <div class="field__item">cancer models</div> <div class="field__item">Cancer</div> <div class="field__item">cancer dependency</div> <div class="field__item">dependency map</div> <div class="field__item">cell line profiling</div> </div> </div> <div class="field field--name-field-broad-tags field--type-entity-reference field--label-above"> <div class="field__label">Ó³»­´«Ã½ tags</div> <div class="field__items"> <div class="field__item"><a href="/broad-tags/cancer-program" hreflang="en">Cancer Program</a></div> <div class="field__item"><a href="/broad-tags/cancer" hreflang="en">Cancer</a></div> </div> </div> Tue, 30 Sep 2025 13:57:45 +0000 Corie Lok 5559426 at /news/study-identifies-genetic-targets-could-improve-car-t-therapies <span class="field field--name-title field--type-string field--label-hidden">Ó³»­´«Ã½-Novartis Cancer Cell Line Encyclopedia (CCLE)</span> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p> The Cancer Cell Line Encyclopedia (CCLE) project is an effort to conduct a detailed genetic characterization of a large panel of human cancer cell lines. The CCLE provides public access analysis and visualization of DNA copy number, mRNA expression, mutation data and more, for 1000 cancer cell lines. The Cancer Cell Line Encyclopedia (CCLE) project is an effort to conduct a detailed genetic characterization of a large panel of human cancer cell lines. The CCLE provides public access analysis and visualization of DNA copy number, mRNA expression, mutation data and more, for 1000 cancer cell lines.</p> <p> <span style="display:none;">cell line profiling</span></p> </div> <span class="field field--name-uid field--type-entity-reference field--label-hidden"> <span>By bistline@broadinstitute.org</span> </span> <span class="field field--name-created field--type-created field--label-hidden"><time datetime="2012-02-16T15:36:59-05:00" title="Thursday, February 16, 2012 - 15:36" class="datetime">February 16, 2012</time> </span> <div class="field field--name-field-software-link field--type-link field--label-above"> <div class="field__label">Link</div> <div class="field__items"> <div class="field__item"><a href="https://portals.broadinstitute.org/ccle/home">CCLE</a></div> </div> </div> <div class="field field--name-field-taxonomy-topic field--type-entity-reference field--label-above"> <div class="field__label">Topic</div> <div class="field__items"> <div class="field__item">cell lines</div> <div class="field__item">CCLE</div> <div class="field__item">cancer portals</div> <div class="field__item">cancer models</div> <div class="field__item">Cancer</div> <div class="field__item">cancer dependency</div> <div class="field__item">dependency map</div> <div class="field__item">cell line profiling</div> </div> </div> <div class="field field--name-field-broad-tags field--type-entity-reference field--label-above"> <div class="field__label">Ó³»­´«Ã½ tags</div> <div class="field__items"> <div class="field__item"><a href="/broad-tags/cancer-program" hreflang="en">Cancer Program</a></div> <div class="field__item"><a href="/broad-tags/cancer" hreflang="en">Cancer</a></div> </div> </div> Wed, 24 Sep 2025 15:01:58 +0000 tulrich@broadinstitute.org 5559411 at /news/new-ai-based-diagnostic-tool-uses-epigenomics-accelerate-acute-leukemia-diagnosis <span class="field field--name-title field--type-string field--label-hidden">Ó³»­´«Ã½-Novartis Cancer Cell Line Encyclopedia (CCLE)</span> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p> The Cancer Cell Line Encyclopedia (CCLE) project is an effort to conduct a detailed genetic characterization of a large panel of human cancer cell lines. The CCLE provides public access analysis and visualization of DNA copy number, mRNA expression, mutation data and more, for 1000 cancer cell lines. The Cancer Cell Line Encyclopedia (CCLE) project is an effort to conduct a detailed genetic characterization of a large panel of human cancer cell lines. The CCLE provides public access analysis and visualization of DNA copy number, mRNA expression, mutation data and more, for 1000 cancer cell lines.</p> <p> <span style="display:none;">cell line profiling</span></p> </div> <span class="field field--name-uid field--type-entity-reference field--label-hidden"> <span>By bistline@broadinstitute.org</span> </span> <span class="field field--name-created field--type-created field--label-hidden"><time datetime="2012-02-16T15:36:59-05:00" title="Thursday, February 16, 2012 - 15:36" class="datetime">February 16, 2012</time> </span> <div class="field field--name-field-software-link field--type-link field--label-above"> <div class="field__label">Link</div> <div class="field__items"> <div class="field__item"><a href="https://portals.broadinstitute.org/ccle/home">CCLE</a></div> </div> </div> <div class="field field--name-field-taxonomy-topic field--type-entity-reference field--label-above"> <div class="field__label">Topic</div> <div class="field__items"> <div class="field__item">cell lines</div> <div class="field__item">CCLE</div> <div class="field__item">cancer portals</div> <div class="field__item">cancer models</div> <div class="field__item">Cancer</div> <div class="field__item">cancer dependency</div> <div class="field__item">dependency map</div> <div class="field__item">cell line profiling</div> </div> </div> <div class="field field--name-field-broad-tags field--type-entity-reference field--label-above"> <div class="field__label">Ó³»­´«Ã½ tags</div> <div class="field__items"> <div class="field__item"><a href="/broad-tags/cancer-program" hreflang="en">Cancer Program</a></div> <div class="field__item"><a href="/broad-tags/cancer" hreflang="en">Cancer</a></div> </div> </div> Mon, 22 Sep 2025 14:00:11 +0000 tulrich@broadinstitute.org 5559416 at /news/whyiscience-qa-structural-biologist-adopts-new-role-catalyzing-collaborations <span class="field field--name-title field--type-string field--label-hidden">Ó³»­´«Ã½-Novartis Cancer Cell Line Encyclopedia (CCLE)</span> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p> The Cancer Cell Line Encyclopedia (CCLE) project is an effort to conduct a detailed genetic characterization of a large panel of human cancer cell lines. The CCLE provides public access analysis and visualization of DNA copy number, mRNA expression, mutation data and more, for 1000 cancer cell lines. The Cancer Cell Line Encyclopedia (CCLE) project is an effort to conduct a detailed genetic characterization of a large panel of human cancer cell lines. The CCLE provides public access analysis and visualization of DNA copy number, mRNA expression, mutation data and more, for 1000 cancer cell lines.</p> <p> <span style="display:none;">cell line profiling</span></p> </div> <span class="field field--name-uid field--type-entity-reference field--label-hidden"> <span>By bistline@broadinstitute.org</span> </span> <span class="field field--name-created field--type-created field--label-hidden"><time datetime="2012-02-16T15:36:59-05:00" title="Thursday, February 16, 2012 - 15:36" class="datetime">February 16, 2012</time> </span> <div class="field field--name-field-software-link field--type-link field--label-above"> <div class="field__label">Link</div> <div class="field__items"> <div class="field__item"><a href="https://portals.broadinstitute.org/ccle/home">CCLE</a></div> </div> </div> <div class="field field--name-field-taxonomy-topic field--type-entity-reference field--label-above"> <div class="field__label">Topic</div> <div class="field__items"> <div class="field__item">cell lines</div> <div class="field__item">CCLE</div> <div class="field__item">cancer portals</div> <div class="field__item">cancer models</div> <div class="field__item">Cancer</div> <div class="field__item">cancer dependency</div> <div class="field__item">dependency map</div> <div class="field__item">cell line profiling</div> </div> </div> <div class="field field--name-field-broad-tags field--type-entity-reference field--label-above"> <div class="field__label">Ó³»­´«Ã½ tags</div> <div class="field__items"> <div class="field__item"><a href="/broad-tags/cancer-program" hreflang="en">Cancer Program</a></div> <div class="field__item"><a href="/broad-tags/cancer" hreflang="en">Cancer</a></div> </div> </div> Wed, 10 Sep 2025 13:22:24 +0000 leah@broadinstitute.org 5559346 at /news/remembering-david-baltimore <span class="field field--name-title field--type-string field--label-hidden">Ó³»­´«Ã½-Novartis Cancer Cell Line Encyclopedia (CCLE)</span> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p> The Cancer Cell Line Encyclopedia (CCLE) project is an effort to conduct a detailed genetic characterization of a large panel of human cancer cell lines. The CCLE provides public access analysis and visualization of DNA copy number, mRNA expression, mutation data and more, for 1000 cancer cell lines. The Cancer Cell Line Encyclopedia (CCLE) project is an effort to conduct a detailed genetic characterization of a large panel of human cancer cell lines. The CCLE provides public access analysis and visualization of DNA copy number, mRNA expression, mutation data and more, for 1000 cancer cell lines.</p> <p> <span style="display:none;">cell line profiling</span></p> </div> <span class="field field--name-uid field--type-entity-reference field--label-hidden"> <span>By bistline@broadinstitute.org</span> </span> <span class="field field--name-created field--type-created field--label-hidden"><time datetime="2012-02-16T15:36:59-05:00" title="Thursday, February 16, 2012 - 15:36" class="datetime">February 16, 2012</time> </span> <div class="field field--name-field-software-link field--type-link field--label-above"> <div class="field__label">Link</div> <div class="field__items"> <div class="field__item"><a href="https://portals.broadinstitute.org/ccle/home">CCLE</a></div> </div> </div> <div class="field field--name-field-taxonomy-topic field--type-entity-reference field--label-above"> <div class="field__label">Topic</div> <div class="field__items"> <div class="field__item">cell lines</div> <div class="field__item">CCLE</div> <div class="field__item">cancer portals</div> <div class="field__item">cancer models</div> <div class="field__item">Cancer</div> <div class="field__item">cancer dependency</div> <div class="field__item">dependency map</div> <div class="field__item">cell line profiling</div> </div> </div> <div class="field field--name-field-broad-tags field--type-entity-reference field--label-above"> <div class="field__label">Ó³»­´«Ã½ tags</div> <div class="field__items"> <div class="field__item"><a href="/broad-tags/cancer-program" hreflang="en">Cancer Program</a></div> <div class="field__item"><a href="/broad-tags/cancer" hreflang="en">Cancer</a></div> </div> </div> Mon, 08 Sep 2025 15:19:08 +0000 mnemchuk@broadinstitute.org 5559341 at /news/mass-general-brigham-launches-genetic-test-predict-risk-across-eight-cardiovascular-conditions <span class="field field--name-title field--type-string field--label-hidden">Ó³»­´«Ã½-Novartis Cancer Cell Line Encyclopedia (CCLE)</span> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p> The Cancer Cell Line Encyclopedia (CCLE) project is an effort to conduct a detailed genetic characterization of a large panel of human cancer cell lines. The CCLE provides public access analysis and visualization of DNA copy number, mRNA expression, mutation data and more, for 1000 cancer cell lines. The Cancer Cell Line Encyclopedia (CCLE) project is an effort to conduct a detailed genetic characterization of a large panel of human cancer cell lines. The CCLE provides public access analysis and visualization of DNA copy number, mRNA expression, mutation data and more, for 1000 cancer cell lines.</p> <p> <span style="display:none;">cell line profiling</span></p> </div> <span class="field field--name-uid field--type-entity-reference field--label-hidden"> <span>By bistline@broadinstitute.org</span> </span> <span class="field field--name-created field--type-created field--label-hidden"><time datetime="2012-02-16T15:36:59-05:00" title="Thursday, February 16, 2012 - 15:36" class="datetime">February 16, 2012</time> </span> <div class="field field--name-field-software-link field--type-link field--label-above"> <div class="field__label">Link</div> <div class="field__items"> <div class="field__item"><a href="https://portals.broadinstitute.org/ccle/home">CCLE</a></div> </div> </div> <div class="field field--name-field-taxonomy-topic field--type-entity-reference field--label-above"> <div class="field__label">Topic</div> <div class="field__items"> <div class="field__item">cell lines</div> <div class="field__item">CCLE</div> <div class="field__item">cancer portals</div> <div class="field__item">cancer models</div> <div class="field__item">Cancer</div> <div class="field__item">cancer dependency</div> <div class="field__item">dependency map</div> <div class="field__item">cell line profiling</div> </div> </div> <div class="field field--name-field-broad-tags field--type-entity-reference field--label-above"> <div class="field__label">Ó³»­´«Ã½ tags</div> <div class="field__items"> <div class="field__item"><a href="/broad-tags/cancer-program" hreflang="en">Cancer Program</a></div> <div class="field__item"><a href="/broad-tags/cancer" hreflang="en">Cancer</a></div> </div> </div> Wed, 03 Sep 2025 21:35:14 +0000 Corie Lok 5559326 at /news/how-massive-datasets-generated-broad-are-powering-latest-ai-models-biology <span class="field field--name-title field--type-string field--label-hidden">Ó³»­´«Ã½-Novartis Cancer Cell Line Encyclopedia (CCLE)</span> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p> The Cancer Cell Line Encyclopedia (CCLE) project is an effort to conduct a detailed genetic characterization of a large panel of human cancer cell lines. The CCLE provides public access analysis and visualization of DNA copy number, mRNA expression, mutation data and more, for 1000 cancer cell lines. The Cancer Cell Line Encyclopedia (CCLE) project is an effort to conduct a detailed genetic characterization of a large panel of human cancer cell lines. The CCLE provides public access analysis and visualization of DNA copy number, mRNA expression, mutation data and more, for 1000 cancer cell lines.</p> <p> <span style="display:none;">cell line profiling</span></p> </div> <span class="field field--name-uid field--type-entity-reference field--label-hidden"> <span>By bistline@broadinstitute.org</span> </span> <span class="field field--name-created field--type-created field--label-hidden"><time datetime="2012-02-16T15:36:59-05:00" title="Thursday, February 16, 2012 - 15:36" class="datetime">February 16, 2012</time> </span> <div class="field field--name-field-software-link field--type-link field--label-above"> <div class="field__label">Link</div> <div class="field__items"> <div class="field__item"><a href="https://portals.broadinstitute.org/ccle/home">CCLE</a></div> </div> </div> <div class="field field--name-field-taxonomy-topic field--type-entity-reference field--label-above"> <div class="field__label">Topic</div> <div class="field__items"> <div class="field__item">cell lines</div> <div class="field__item">CCLE</div> <div class="field__item">cancer portals</div> <div class="field__item">cancer models</div> <div class="field__item">Cancer</div> <div class="field__item">cancer dependency</div> <div class="field__item">dependency map</div> <div class="field__item">cell line profiling</div> </div> </div> <div class="field field--name-field-broad-tags field--type-entity-reference field--label-above"> <div class="field__label">Ó³»­´«Ã½ tags</div> <div class="field__items"> <div class="field__item"><a href="/broad-tags/cancer-program" hreflang="en">Cancer Program</a></div> <div class="field__item"><a href="/broad-tags/cancer" hreflang="en">Cancer</a></div> </div> </div> Wed, 03 Sep 2025 18:10:36 +0000 tulrich@broadinstitute.org 5559316 at /news/breast-cancer-therapy-can-raise-uterine-cancer-risk-through-unique-mechanism <span class="field field--name-title field--type-string field--label-hidden">Ó³»­´«Ã½-Novartis Cancer Cell Line Encyclopedia (CCLE)</span> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p> The Cancer Cell Line Encyclopedia (CCLE) project is an effort to conduct a detailed genetic characterization of a large panel of human cancer cell lines. The CCLE provides public access analysis and visualization of DNA copy number, mRNA expression, mutation data and more, for 1000 cancer cell lines. The Cancer Cell Line Encyclopedia (CCLE) project is an effort to conduct a detailed genetic characterization of a large panel of human cancer cell lines. The CCLE provides public access analysis and visualization of DNA copy number, mRNA expression, mutation data and more, for 1000 cancer cell lines.</p> <p> <span style="display:none;">cell line profiling</span></p> </div> <span class="field field--name-uid field--type-entity-reference field--label-hidden"> <span>By bistline@broadinstitute.org</span> </span> <span class="field field--name-created field--type-created field--label-hidden"><time datetime="2012-02-16T15:36:59-05:00" title="Thursday, February 16, 2012 - 15:36" class="datetime">February 16, 2012</time> </span> <div class="field field--name-field-software-link field--type-link field--label-above"> <div class="field__label">Link</div> <div class="field__items"> <div class="field__item"><a href="https://portals.broadinstitute.org/ccle/home">CCLE</a></div> </div> </div> <div class="field field--name-field-taxonomy-topic field--type-entity-reference field--label-above"> <div class="field__label">Topic</div> <div class="field__items"> <div class="field__item">cell lines</div> <div class="field__item">CCLE</div> <div class="field__item">cancer portals</div> <div class="field__item">cancer models</div> <div class="field__item">Cancer</div> <div class="field__item">cancer dependency</div> <div class="field__item">dependency map</div> <div class="field__item">cell line profiling</div> </div> </div> <div class="field field--name-field-broad-tags field--type-entity-reference field--label-above"> <div class="field__label">Ó³»­´«Ã½ tags</div> <div class="field__items"> <div class="field__item"><a href="/broad-tags/cancer-program" hreflang="en">Cancer Program</a></div> <div class="field__item"><a href="/broad-tags/cancer" hreflang="en">Cancer</a></div> </div> </div> Fri, 22 Aug 2025 14:01:54 +0000 tulrich@broadinstitute.org 5559301 at /news/using-ai-researchers-design-new-compounds-kill-antibiotic-resistant-bacteria <span class="field field--name-title field--type-string field--label-hidden">Ó³»­´«Ã½-Novartis Cancer Cell Line Encyclopedia (CCLE)</span> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p> The Cancer Cell Line Encyclopedia (CCLE) project is an effort to conduct a detailed genetic characterization of a large panel of human cancer cell lines. The CCLE provides public access analysis and visualization of DNA copy number, mRNA expression, mutation data and more, for 1000 cancer cell lines. The Cancer Cell Line Encyclopedia (CCLE) project is an effort to conduct a detailed genetic characterization of a large panel of human cancer cell lines. The CCLE provides public access analysis and visualization of DNA copy number, mRNA expression, mutation data and more, for 1000 cancer cell lines.</p> <p> <span style="display:none;">cell line profiling</span></p> </div> <span class="field field--name-uid field--type-entity-reference field--label-hidden"> <span>By bistline@broadinstitute.org</span> </span> <span class="field field--name-created field--type-created field--label-hidden"><time datetime="2012-02-16T15:36:59-05:00" title="Thursday, February 16, 2012 - 15:36" class="datetime">February 16, 2012</time> </span> <div class="field field--name-field-software-link field--type-link field--label-above"> <div class="field__label">Link</div> <div class="field__items"> <div class="field__item"><a href="https://portals.broadinstitute.org/ccle/home">CCLE</a></div> </div> </div> <div class="field field--name-field-taxonomy-topic field--type-entity-reference field--label-above"> <div class="field__label">Topic</div> <div class="field__items"> <div class="field__item">cell lines</div> <div class="field__item">CCLE</div> <div class="field__item">cancer portals</div> <div class="field__item">cancer models</div> <div class="field__item">Cancer</div> <div class="field__item">cancer dependency</div> <div class="field__item">dependency map</div> <div class="field__item">cell line profiling</div> </div> </div> <div class="field field--name-field-broad-tags field--type-entity-reference field--label-above"> <div class="field__label">Ó³»­´«Ã½ tags</div> <div class="field__items"> <div class="field__item"><a href="/broad-tags/cancer-program" hreflang="en">Cancer Program</a></div> <div class="field__item"><a href="/broad-tags/cancer" hreflang="en">Cancer</a></div> </div> </div> Fri, 15 Aug 2025 13:02:05 +0000 tulrich@broadinstitute.org 5559321 at