/ en Wed, 16 Feb 22 11:16:47 -0500 /how-broad-scientists-are-bridging-gap-between-biological-insights-and-new-therapies <span class="field field--name-title field--type-string field--label-hidden">CTD^2 Dashboard</span> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p> The CTD<sup>2</sup> Dashboard is a web resource that links findings from Cancer Target Discovery and Development (CTD<sup>2</sup>) Network Centers, which collectively mine and functionally validate data from large-scale cancer genome characterization initiatives and advance them toward use in precision oncology. The Network developed the open-access CTD<sup>2</sup> Dashboard as a web interface that compiles Network-generated summaries about key cancer biology findings and cancer-relevant results related to genes, proteins, and compounds. Dashboard submissions are ranked with a system of validation tiers to indicate strength of evidence.</p> <p> <strong>Publications</strong></p> <p> <a href="https://www.ncbi.nlm.nih.gov/pubmed/29220450" target="_blank">https://www.ncbi.nlm.nih.gov/pubmed/29220450</a></p> <p> <span style="display:none;">cell line profiling</span></p> </div> <span class="field field--name-uid field--type-entity-reference field--label-hidden"> <span>By Maria Nemchuk</span> </span> <span class="field field--name-created field--type-created field--label-hidden"><time datetime="2017-05-04T11:44:53-04:00" title="Thursday, May 4, 2017 - 11:44" class="datetime">May 4, 2017</time> </span> <div class="field field--name-field-software-link field--type-link field--label-above"> <div class="field__label">Link</div> <div class="field__items"> <div class="field__item"><a href="https://ctd2-dashboard.nci.nih.gov/dashboard/">CTD^2 Dashboard</a></div> </div> </div> <div class="field field--name-field-taxonomy-topic field--type-entity-reference field--label-above"> <div class="field__label">Topic</div> <div class="field__items"> <div class="field__item">Portals</div> <div class="field__item">Cancer</div> <div class="field__item">cell line profiling</div> <div class="field__item">small molecules</div> <div class="field__item">Therapeutic Response</div> </div> </div> <div class="field field--name-field-broad-tags field--type-entity-reference field--label-above"> <div class="field__label">Ó³»­´«Ã½ tags</div> <div class="field__items"> <div class="field__item"><a href="/broad-tags/chemical-biology-and-therapeutics-science" hreflang="en">Chemical Biology and Therapeutics Science Program</a></div> <div class="field__item"><a href="/broad-tags/cancer" hreflang="en">Cancer</a></div> <div class="field__item"><a href="/broad-tags/paul-clemons" hreflang="en">Paul Clemons</a></div> <div class="field__item"><a href="/broad-tags/stuart-schreiber" hreflang="en">Stuart Schreiber</a></div> </div> </div> Wed, 16 Feb 2022 16:16:47 +0000 adicorat 1127161 at /news/how-lung-injury-study-helped-inspire-new-covid-19-drug-trials <span class="field field--name-title field--type-string field--label-hidden">CTD^2 Dashboard</span> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p> The CTD<sup>2</sup> Dashboard is a web resource that links findings from Cancer Target Discovery and Development (CTD<sup>2</sup>) Network Centers, which collectively mine and functionally validate data from large-scale cancer genome characterization initiatives and advance them toward use in precision oncology. The Network developed the open-access CTD<sup>2</sup> Dashboard as a web interface that compiles Network-generated summaries about key cancer biology findings and cancer-relevant results related to genes, proteins, and compounds. Dashboard submissions are ranked with a system of validation tiers to indicate strength of evidence.</p> <p> <strong>Publications</strong></p> <p> <a href="https://www.ncbi.nlm.nih.gov/pubmed/29220450" target="_blank">https://www.ncbi.nlm.nih.gov/pubmed/29220450</a></p> <p> <span style="display:none;">cell line profiling</span></p> </div> <span class="field field--name-uid field--type-entity-reference field--label-hidden"> <span>By Maria Nemchuk</span> </span> <span class="field field--name-created field--type-created field--label-hidden"><time datetime="2017-05-04T11:44:53-04:00" title="Thursday, May 4, 2017 - 11:44" class="datetime">May 4, 2017</time> </span> <div class="field field--name-field-software-link field--type-link field--label-above"> <div class="field__label">Link</div> <div class="field__items"> <div class="field__item"><a href="https://ctd2-dashboard.nci.nih.gov/dashboard/">CTD^2 Dashboard</a></div> </div> </div> <div class="field field--name-field-taxonomy-topic field--type-entity-reference field--label-above"> <div class="field__label">Topic</div> <div class="field__items"> <div class="field__item">Portals</div> <div class="field__item">Cancer</div> <div class="field__item">cell line profiling</div> <div class="field__item">small molecules</div> <div class="field__item">Therapeutic Response</div> </div> </div> <div class="field field--name-field-broad-tags field--type-entity-reference field--label-above"> <div class="field__label">Ó³»­´«Ã½ tags</div> <div class="field__items"> <div class="field__item"><a href="/broad-tags/chemical-biology-and-therapeutics-science" hreflang="en">Chemical Biology and Therapeutics Science Program</a></div> <div class="field__item"><a href="/broad-tags/cancer" hreflang="en">Cancer</a></div> <div class="field__item"><a href="/broad-tags/paul-clemons" hreflang="en">Paul Clemons</a></div> <div class="field__item"><a href="/broad-tags/stuart-schreiber" hreflang="en">Stuart Schreiber</a></div> </div> </div> Tue, 17 Nov 2020 16:39:16 +0000 Corie Lok 683186 at /news/researchers-discover-new-member-novel-drug-family-%E2%80%98undruggable%E2%80%99-targets <span class="field field--name-title field--type-string field--label-hidden">CTD^2 Dashboard</span> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p> The CTD<sup>2</sup> Dashboard is a web resource that links findings from Cancer Target Discovery and Development (CTD<sup>2</sup>) Network Centers, which collectively mine and functionally validate data from large-scale cancer genome characterization initiatives and advance them toward use in precision oncology. The Network developed the open-access CTD<sup>2</sup> Dashboard as a web interface that compiles Network-generated summaries about key cancer biology findings and cancer-relevant results related to genes, proteins, and compounds. Dashboard submissions are ranked with a system of validation tiers to indicate strength of evidence.</p> <p> <strong>Publications</strong></p> <p> <a href="https://www.ncbi.nlm.nih.gov/pubmed/29220450" target="_blank">https://www.ncbi.nlm.nih.gov/pubmed/29220450</a></p> <p> <span style="display:none;">cell line profiling</span></p> </div> <span class="field field--name-uid field--type-entity-reference field--label-hidden"> <span>By Maria Nemchuk</span> </span> <span class="field field--name-created field--type-created field--label-hidden"><time datetime="2017-05-04T11:44:53-04:00" title="Thursday, May 4, 2017 - 11:44" class="datetime">May 4, 2017</time> </span> <div class="field field--name-field-software-link field--type-link field--label-above"> <div class="field__label">Link</div> <div class="field__items"> <div class="field__item"><a href="https://ctd2-dashboard.nci.nih.gov/dashboard/">CTD^2 Dashboard</a></div> </div> </div> <div class="field field--name-field-taxonomy-topic field--type-entity-reference field--label-above"> <div class="field__label">Topic</div> <div class="field__items"> <div class="field__item">Portals</div> <div class="field__item">Cancer</div> <div class="field__item">cell line profiling</div> <div class="field__item">small molecules</div> <div class="field__item">Therapeutic Response</div> </div> </div> <div class="field field--name-field-broad-tags field--type-entity-reference field--label-above"> <div class="field__label">Ó³»­´«Ã½ tags</div> <div class="field__items"> <div class="field__item"><a href="/broad-tags/chemical-biology-and-therapeutics-science" hreflang="en">Chemical Biology and Therapeutics Science Program</a></div> <div class="field__item"><a href="/broad-tags/cancer" hreflang="en">Cancer</a></div> <div class="field__item"><a href="/broad-tags/paul-clemons" hreflang="en">Paul Clemons</a></div> <div class="field__item"><a href="/broad-tags/stuart-schreiber" hreflang="en">Stuart Schreiber</a></div> </div> </div> Thu, 04 Jun 2020 12:47:59 +0000 Corie Lok 630376 at /blog/combing-through-old-drugs-find-new-ones-covid-19 <span class="field field--name-title field--type-string field--label-hidden">CTD^2 Dashboard</span> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p> The CTD<sup>2</sup> Dashboard is a web resource that links findings from Cancer Target Discovery and Development (CTD<sup>2</sup>) Network Centers, which collectively mine and functionally validate data from large-scale cancer genome characterization initiatives and advance them toward use in precision oncology. The Network developed the open-access CTD<sup>2</sup> Dashboard as a web interface that compiles Network-generated summaries about key cancer biology findings and cancer-relevant results related to genes, proteins, and compounds. Dashboard submissions are ranked with a system of validation tiers to indicate strength of evidence.</p> <p> <strong>Publications</strong></p> <p> <a href="https://www.ncbi.nlm.nih.gov/pubmed/29220450" target="_blank">https://www.ncbi.nlm.nih.gov/pubmed/29220450</a></p> <p> <span style="display:none;">cell line profiling</span></p> </div> <span class="field field--name-uid field--type-entity-reference field--label-hidden"> <span>By Maria Nemchuk</span> </span> <span class="field field--name-created field--type-created field--label-hidden"><time datetime="2017-05-04T11:44:53-04:00" title="Thursday, May 4, 2017 - 11:44" class="datetime">May 4, 2017</time> </span> <div class="field field--name-field-software-link field--type-link field--label-above"> <div class="field__label">Link</div> <div class="field__items"> <div class="field__item"><a href="https://ctd2-dashboard.nci.nih.gov/dashboard/">CTD^2 Dashboard</a></div> </div> </div> <div class="field field--name-field-taxonomy-topic field--type-entity-reference field--label-above"> <div class="field__label">Topic</div> <div class="field__items"> <div class="field__item">Portals</div> <div class="field__item">Cancer</div> <div class="field__item">cell line profiling</div> <div class="field__item">small molecules</div> <div class="field__item">Therapeutic Response</div> </div> </div> <div class="field field--name-field-broad-tags field--type-entity-reference field--label-above"> <div class="field__label">Ó³»­´«Ã½ tags</div> <div class="field__items"> <div class="field__item"><a href="/broad-tags/chemical-biology-and-therapeutics-science" hreflang="en">Chemical Biology and Therapeutics Science Program</a></div> <div class="field__item"><a href="/broad-tags/cancer" hreflang="en">Cancer</a></div> <div class="field__item"><a href="/broad-tags/paul-clemons" hreflang="en">Paul Clemons</a></div> <div class="field__item"><a href="/broad-tags/stuart-schreiber" hreflang="en">Stuart Schreiber</a></div> </div> </div> Tue, 12 May 2020 13:48:25 +0000 Namrata Sengupta 628861 at /news/dozens-non-oncology-drugs-can-kill-cancer-cells <span class="field field--name-title field--type-string field--label-hidden">CTD^2 Dashboard</span> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p> The CTD<sup>2</sup> Dashboard is a web resource that links findings from Cancer Target Discovery and Development (CTD<sup>2</sup>) Network Centers, which collectively mine and functionally validate data from large-scale cancer genome characterization initiatives and advance them toward use in precision oncology. The Network developed the open-access CTD<sup>2</sup> Dashboard as a web interface that compiles Network-generated summaries about key cancer biology findings and cancer-relevant results related to genes, proteins, and compounds. Dashboard submissions are ranked with a system of validation tiers to indicate strength of evidence.</p> <p> <strong>Publications</strong></p> <p> <a href="https://www.ncbi.nlm.nih.gov/pubmed/29220450" target="_blank">https://www.ncbi.nlm.nih.gov/pubmed/29220450</a></p> <p> <span style="display:none;">cell line profiling</span></p> </div> <span class="field field--name-uid field--type-entity-reference field--label-hidden"> <span>By Maria Nemchuk</span> </span> <span class="field field--name-created field--type-created field--label-hidden"><time datetime="2017-05-04T11:44:53-04:00" title="Thursday, May 4, 2017 - 11:44" class="datetime">May 4, 2017</time> </span> <div class="field field--name-field-software-link field--type-link field--label-above"> <div class="field__label">Link</div> <div class="field__items"> <div class="field__item"><a href="https://ctd2-dashboard.nci.nih.gov/dashboard/">CTD^2 Dashboard</a></div> </div> </div> <div class="field field--name-field-taxonomy-topic field--type-entity-reference field--label-above"> <div class="field__label">Topic</div> <div class="field__items"> <div class="field__item">Portals</div> <div class="field__item">Cancer</div> <div class="field__item">cell line profiling</div> <div class="field__item">small molecules</div> <div class="field__item">Therapeutic Response</div> </div> </div> <div class="field field--name-field-broad-tags field--type-entity-reference field--label-above"> <div class="field__label">Ó³»­´«Ã½ tags</div> <div class="field__items"> <div class="field__item"><a href="/broad-tags/chemical-biology-and-therapeutics-science" hreflang="en">Chemical Biology and Therapeutics Science Program</a></div> <div class="field__item"><a href="/broad-tags/cancer" hreflang="en">Cancer</a></div> <div class="field__item"><a href="/broad-tags/paul-clemons" hreflang="en">Paul Clemons</a></div> <div class="field__item"><a href="/broad-tags/stuart-schreiber" hreflang="en">Stuart Schreiber</a></div> </div> </div> Mon, 20 Jan 2020 16:00:00 +0000 leah@broadinstitute.org 626841 at /drug-repurposing-hub <span class="field field--name-title field--type-string field--label-hidden">CTD^2 Dashboard</span> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p> The CTD<sup>2</sup> Dashboard is a web resource that links findings from Cancer Target Discovery and Development (CTD<sup>2</sup>) Network Centers, which collectively mine and functionally validate data from large-scale cancer genome characterization initiatives and advance them toward use in precision oncology. The Network developed the open-access CTD<sup>2</sup> Dashboard as a web interface that compiles Network-generated summaries about key cancer biology findings and cancer-relevant results related to genes, proteins, and compounds. Dashboard submissions are ranked with a system of validation tiers to indicate strength of evidence.</p> <p> <strong>Publications</strong></p> <p> <a href="https://www.ncbi.nlm.nih.gov/pubmed/29220450" target="_blank">https://www.ncbi.nlm.nih.gov/pubmed/29220450</a></p> <p> <span style="display:none;">cell line profiling</span></p> </div> <span class="field field--name-uid field--type-entity-reference field--label-hidden"> <span>By Maria Nemchuk</span> </span> <span class="field field--name-created field--type-created field--label-hidden"><time datetime="2017-05-04T11:44:53-04:00" title="Thursday, May 4, 2017 - 11:44" class="datetime">May 4, 2017</time> </span> <div class="field field--name-field-software-link field--type-link field--label-above"> <div class="field__label">Link</div> <div class="field__items"> <div class="field__item"><a href="https://ctd2-dashboard.nci.nih.gov/dashboard/">CTD^2 Dashboard</a></div> </div> </div> <div class="field field--name-field-taxonomy-topic field--type-entity-reference field--label-above"> <div class="field__label">Topic</div> <div class="field__items"> <div class="field__item">Portals</div> <div class="field__item">Cancer</div> <div class="field__item">cell line profiling</div> <div class="field__item">small molecules</div> <div class="field__item">Therapeutic Response</div> </div> </div> <div class="field field--name-field-broad-tags field--type-entity-reference field--label-above"> <div class="field__label">Ó³»­´«Ã½ tags</div> <div class="field__items"> <div class="field__item"><a href="/broad-tags/chemical-biology-and-therapeutics-science" hreflang="en">Chemical Biology and Therapeutics Science Program</a></div> <div class="field__item"><a href="/broad-tags/cancer" hreflang="en">Cancer</a></div> <div class="field__item"><a href="/broad-tags/paul-clemons" hreflang="en">Paul Clemons</a></div> <div class="field__item"><a href="/broad-tags/stuart-schreiber" hreflang="en">Stuart Schreiber</a></div> </div> </div> Thu, 25 Jul 2019 21:21:33 +0000 mnemchuk@broadinstitute.org 573896 at /news/molecular-traffic-jam-may-underlie-rare-kidney-disease-and-several-other-protein-misfolding <span class="field field--name-title field--type-string field--label-hidden">CTD^2 Dashboard</span> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p> The CTD<sup>2</sup> Dashboard is a web resource that links findings from Cancer Target Discovery and Development (CTD<sup>2</sup>) Network Centers, which collectively mine and functionally validate data from large-scale cancer genome characterization initiatives and advance them toward use in precision oncology. The Network developed the open-access CTD<sup>2</sup> Dashboard as a web interface that compiles Network-generated summaries about key cancer biology findings and cancer-relevant results related to genes, proteins, and compounds. Dashboard submissions are ranked with a system of validation tiers to indicate strength of evidence.</p> <p> <strong>Publications</strong></p> <p> <a href="https://www.ncbi.nlm.nih.gov/pubmed/29220450" target="_blank">https://www.ncbi.nlm.nih.gov/pubmed/29220450</a></p> <p> <span style="display:none;">cell line profiling</span></p> </div> <span class="field field--name-uid field--type-entity-reference field--label-hidden"> <span>By Maria Nemchuk</span> </span> <span class="field field--name-created field--type-created field--label-hidden"><time datetime="2017-05-04T11:44:53-04:00" title="Thursday, May 4, 2017 - 11:44" class="datetime">May 4, 2017</time> </span> <div class="field field--name-field-software-link field--type-link field--label-above"> <div class="field__label">Link</div> <div class="field__items"> <div class="field__item"><a href="https://ctd2-dashboard.nci.nih.gov/dashboard/">CTD^2 Dashboard</a></div> </div> </div> <div class="field field--name-field-taxonomy-topic field--type-entity-reference field--label-above"> <div class="field__label">Topic</div> <div class="field__items"> <div class="field__item">Portals</div> <div class="field__item">Cancer</div> <div class="field__item">cell line profiling</div> <div class="field__item">small molecules</div> <div class="field__item">Therapeutic Response</div> </div> </div> <div class="field field--name-field-broad-tags field--type-entity-reference field--label-above"> <div class="field__label">Ó³»­´«Ã½ tags</div> <div class="field__items"> <div class="field__item"><a href="/broad-tags/chemical-biology-and-therapeutics-science" hreflang="en">Chemical Biology and Therapeutics Science Program</a></div> <div class="field__item"><a href="/broad-tags/cancer" hreflang="en">Cancer</a></div> <div class="field__item"><a href="/broad-tags/paul-clemons" hreflang="en">Paul Clemons</a></div> <div class="field__item"><a href="/broad-tags/stuart-schreiber" hreflang="en">Stuart Schreiber</a></div> </div> </div> Thu, 25 Jul 2019 15:00:54 +0000 tulrich@broadinstitute.org 571761 at /news/hub-medicines-hiding-tricks-their-sleeves <span class="field field--name-title field--type-string field--label-hidden">CTD^2 Dashboard</span> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p> The CTD<sup>2</sup> Dashboard is a web resource that links findings from Cancer Target Discovery and Development (CTD<sup>2</sup>) Network Centers, which collectively mine and functionally validate data from large-scale cancer genome characterization initiatives and advance them toward use in precision oncology. The Network developed the open-access CTD<sup>2</sup> Dashboard as a web interface that compiles Network-generated summaries about key cancer biology findings and cancer-relevant results related to genes, proteins, and compounds. Dashboard submissions are ranked with a system of validation tiers to indicate strength of evidence.</p> <p> <strong>Publications</strong></p> <p> <a href="https://www.ncbi.nlm.nih.gov/pubmed/29220450" target="_blank">https://www.ncbi.nlm.nih.gov/pubmed/29220450</a></p> <p> <span style="display:none;">cell line profiling</span></p> </div> <span class="field field--name-uid field--type-entity-reference field--label-hidden"> <span>By Maria Nemchuk</span> </span> <span class="field field--name-created field--type-created field--label-hidden"><time datetime="2017-05-04T11:44:53-04:00" title="Thursday, May 4, 2017 - 11:44" class="datetime">May 4, 2017</time> </span> <div class="field field--name-field-software-link field--type-link field--label-above"> <div class="field__label">Link</div> <div class="field__items"> <div class="field__item"><a href="https://ctd2-dashboard.nci.nih.gov/dashboard/">CTD^2 Dashboard</a></div> </div> </div> <div class="field field--name-field-taxonomy-topic field--type-entity-reference field--label-above"> <div class="field__label">Topic</div> <div class="field__items"> <div class="field__item">Portals</div> <div class="field__item">Cancer</div> <div class="field__item">cell line profiling</div> <div class="field__item">small molecules</div> <div class="field__item">Therapeutic Response</div> </div> </div> <div class="field field--name-field-broad-tags field--type-entity-reference field--label-above"> <div class="field__label">Ó³»­´«Ã½ tags</div> <div class="field__items"> <div class="field__item"><a href="/broad-tags/chemical-biology-and-therapeutics-science" hreflang="en">Chemical Biology and Therapeutics Science Program</a></div> <div class="field__item"><a href="/broad-tags/cancer" hreflang="en">Cancer</a></div> <div class="field__item"><a href="/broad-tags/paul-clemons" hreflang="en">Paul Clemons</a></div> <div class="field__item"><a href="/broad-tags/stuart-schreiber" hreflang="en">Stuart Schreiber</a></div> </div> </div> Mon, 14 May 2018 16:00:18 +0000 tulrich@broadinstitute.org 21236 at