Using genomics to predict disease risk

Using genomics to predict disease risk / en Mon, 19 Feb 24 11:00:28 -0500 Genetic risk prediction for 10 chronic diseases moves closer to the clinic /news/genetic-risk-prediction-10-chronic-diseases-moves-closer-clinic <span class="field field--name-title field--type-string field--label-hidden">ӳ��ý-Novartis Cancer Cell Line Encyclopedia (CCLE)</span> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p> The Cancer Cell Line Encyclopedia (CCLE) project is an effort to conduct a detailed genetic characterization of a large panel of human cancer cell lines. The CCLE provides public access analysis and visualization of DNA copy number, mRNA expression, mutation data and more, for 1000 cancer cell lines. The Cancer Cell Line Encyclopedia (CCLE) project is an effort to conduct a detailed genetic characterization of a large panel of human cancer cell lines. The CCLE provides public access analysis and visualization of DNA copy number, mRNA expression, mutation data and more, for 1000 cancer cell lines.</p> <p> <span style="display:none;">cell line profiling</span></p> </div> <span class="field field--name-uid field--type-entity-reference field--label-hidden"> <span>By bistline@broadinstitute.org</span> </span> <span class="field field--name-created field--type-created field--label-hidden"><time datetime="2012-02-16T15:36:59-05:00" title="Thursday, February 16, 2012 - 15:36" class="datetime">February 16, 2012</time> </span> <div class="field field--name-field-software-link field--type-link field--label-above"> <div class="field__label">Link</div> <div class="field__items"> <div class="field__item"><a href="https://portals.broadinstitute.org/ccle/home">CCLE</a></div> </div> </div> <div class="field field--name-field-taxonomy-topic field--type-entity-reference field--label-above"> <div class="field__label">Topic</div> <div class="field__items"> <div class="field__item">cell lines</div> <div class="field__item">CCLE</div> <div class="field__item">cancer portals</div> <div class="field__item">cancer models</div> <div class="field__item">Cancer</div> <div class="field__item">cancer dependency</div> <div class="field__item">dependency map</div> <div class="field__item">cell line profiling</div> </div> </div> <div class="field field--name-field-broad-tags field--type-entity-reference field--label-above"> <div class="field__label">ӳ��ý tags</div> <div class="field__items"> <div class="field__item"><a href="/broad-tags/cancer-program" hreflang="en">Cancer Program</a></div> <div class="field__item"><a href="/broad-tags/cancer" hreflang="en">Cancer</a></div> </div> </div> Mon, 19 Feb 2024 16:00:28 +0000 Corie Lok 5556476 at A scientist devotes her career to tackling inequity in genomics /news/scientist-devotes-her-career-tackling-inequity-genomics <span class="field field--name-title field--type-string field--label-hidden">ӳ��ý-Novartis Cancer Cell Line Encyclopedia (CCLE)</span> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p> The Cancer Cell Line Encyclopedia (CCLE) project is an effort to conduct a detailed genetic characterization of a large panel of human cancer cell lines. The CCLE provides public access analysis and visualization of DNA copy number, mRNA expression, mutation data and more, for 1000 cancer cell lines. The Cancer Cell Line Encyclopedia (CCLE) project is an effort to conduct a detailed genetic characterization of a large panel of human cancer cell lines. The CCLE provides public access analysis and visualization of DNA copy number, mRNA expression, mutation data and more, for 1000 cancer cell lines.</p> <p> <span style="display:none;">cell line profiling</span></p> </div> <span class="field field--name-uid field--type-entity-reference field--label-hidden"> <span>By bistline@broadinstitute.org</span> </span> <span class="field field--name-created field--type-created field--label-hidden"><time datetime="2012-02-16T15:36:59-05:00" title="Thursday, February 16, 2012 - 15:36" class="datetime">February 16, 2012</time> </span> <div class="field field--name-field-software-link field--type-link field--label-above"> <div class="field__label">Link</div> <div class="field__items"> <div class="field__item"><a href="https://portals.broadinstitute.org/ccle/home">CCLE</a></div> </div> </div> <div class="field field--name-field-taxonomy-topic field--type-entity-reference field--label-above"> <div class="field__label">Topic</div> <div class="field__items"> <div class="field__item">cell lines</div> <div class="field__item">CCLE</div> <div class="field__item">cancer portals</div> <div class="field__item">cancer models</div> <div class="field__item">Cancer</div> <div class="field__item">cancer dependency</div> <div class="field__item">dependency map</div> <div class="field__item">cell line profiling</div> </div> </div> <div class="field field--name-field-broad-tags field--type-entity-reference field--label-above"> <div class="field__label">ӳ��ý tags</div> <div class="field__items"> <div class="field__item"><a href="/broad-tags/cancer-program" hreflang="en">Cancer Program</a></div> <div class="field__item"><a href="/broad-tags/cancer" hreflang="en">Cancer</a></div> </div> </div> Mon, 10 Jul 2023 15:00:00 +0000 adicorat 1282196 at More diverse datasets lead to better genetic risk prediction for heart disease /news/more-diverse-datasets-lead-better-genetic-risk-prediction-heart-disease <span class="field field--name-title field--type-string field--label-hidden">ӳ��ý-Novartis Cancer Cell Line Encyclopedia (CCLE)</span> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p> The Cancer Cell Line Encyclopedia (CCLE) project is an effort to conduct a detailed genetic characterization of a large panel of human cancer cell lines. The CCLE provides public access analysis and visualization of DNA copy number, mRNA expression, mutation data and more, for 1000 cancer cell lines. The Cancer Cell Line Encyclopedia (CCLE) project is an effort to conduct a detailed genetic characterization of a large panel of human cancer cell lines. The CCLE provides public access analysis and visualization of DNA copy number, mRNA expression, mutation data and more, for 1000 cancer cell lines.</p> <p> <span style="display:none;">cell line profiling</span></p> </div> <span class="field field--name-uid field--type-entity-reference field--label-hidden"> <span>By bistline@broadinstitute.org</span> </span> <span class="field field--name-created field--type-created field--label-hidden"><time datetime="2012-02-16T15:36:59-05:00" title="Thursday, February 16, 2012 - 15:36" class="datetime">February 16, 2012</time> </span> <div class="field field--name-field-software-link field--type-link field--label-above"> <div class="field__label">Link</div> <div class="field__items"> <div class="field__item"><a href="https://portals.broadinstitute.org/ccle/home">CCLE</a></div> </div> </div> <div class="field field--name-field-taxonomy-topic field--type-entity-reference field--label-above"> <div class="field__label">Topic</div> <div class="field__items"> <div class="field__item">cell lines</div> <div class="field__item">CCLE</div> <div class="field__item">cancer portals</div> <div class="field__item">cancer models</div> <div class="field__item">Cancer</div> <div class="field__item">cancer dependency</div> <div class="field__item">dependency map</div> <div class="field__item">cell line profiling</div> </div> </div> <div class="field field--name-field-broad-tags field--type-entity-reference field--label-above"> <div class="field__label">ӳ��ý tags</div> <div class="field__items"> <div class="field__item"><a href="/broad-tags/cancer-program" hreflang="en">Cancer Program</a></div> <div class="field__item"><a href="/broad-tags/cancer" hreflang="en">Cancer</a></div> </div> </div> Thu, 06 Jul 2023 15:00:00 +0000 leah@broadinstitute.org 1282446 at Rare genetic variants can reveal much about disease biology /news/rare-genetic-variants-can-reveal-much-about-disease-biology <span class="field field--name-title field--type-string field--label-hidden">ӳ��ý-Novartis Cancer Cell Line Encyclopedia (CCLE)</span> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p> The Cancer Cell Line Encyclopedia (CCLE) project is an effort to conduct a detailed genetic characterization of a large panel of human cancer cell lines. The CCLE provides public access analysis and visualization of DNA copy number, mRNA expression, mutation data and more, for 1000 cancer cell lines. The Cancer Cell Line Encyclopedia (CCLE) project is an effort to conduct a detailed genetic characterization of a large panel of human cancer cell lines. The CCLE provides public access analysis and visualization of DNA copy number, mRNA expression, mutation data and more, for 1000 cancer cell lines.</p> <p> <span style="display:none;">cell line profiling</span></p> </div> <span class="field field--name-uid field--type-entity-reference field--label-hidden"> <span>By bistline@broadinstitute.org</span> </span> <span class="field field--name-created field--type-created field--label-hidden"><time datetime="2012-02-16T15:36:59-05:00" title="Thursday, February 16, 2012 - 15:36" class="datetime">February 16, 2012</time> </span> <div class="field field--name-field-software-link field--type-link field--label-above"> <div class="field__label">Link</div> <div class="field__items"> <div class="field__item"><a href="https://portals.broadinstitute.org/ccle/home">CCLE</a></div> </div> </div> <div class="field field--name-field-taxonomy-topic field--type-entity-reference field--label-above"> <div class="field__label">Topic</div> <div class="field__items"> <div class="field__item">cell lines</div> <div class="field__item">CCLE</div> <div class="field__item">cancer portals</div> <div class="field__item">cancer models</div> <div class="field__item">Cancer</div> <div class="field__item">cancer dependency</div> <div class="field__item">dependency map</div> <div class="field__item">cell line profiling</div> </div> </div> <div class="field field--name-field-broad-tags field--type-entity-reference field--label-above"> <div class="field__label">ӳ��ý tags</div> <div class="field__items"> <div class="field__item"><a href="/broad-tags/cancer-program" hreflang="en">Cancer Program</a></div> <div class="field__item"><a href="/broad-tags/cancer" hreflang="en">Cancer</a></div> </div> </div> Wed, 08 Feb 2023 22:39:07 +0000 tulrich@broadinstitute.org 1281666 at ӳ��ý Discovery Center in Cambridge opens to the public this October /news/broad-discovery-center-cambridge-opens-public-october <span class="field field--name-title field--type-string field--label-hidden">ӳ��ý-Novartis Cancer Cell Line Encyclopedia (CCLE)</span> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p> The Cancer Cell Line Encyclopedia (CCLE) project is an effort to conduct a detailed genetic characterization of a large panel of human cancer cell lines. The CCLE provides public access analysis and visualization of DNA copy number, mRNA expression, mutation data and more, for 1000 cancer cell lines. The Cancer Cell Line Encyclopedia (CCLE) project is an effort to conduct a detailed genetic characterization of a large panel of human cancer cell lines. The CCLE provides public access analysis and visualization of DNA copy number, mRNA expression, mutation data and more, for 1000 cancer cell lines.</p> <p> <span style="display:none;">cell line profiling</span></p> </div> <span class="field field--name-uid field--type-entity-reference field--label-hidden"> <span>By bistline@broadinstitute.org</span> </span> <span class="field field--name-created field--type-created field--label-hidden"><time datetime="2012-02-16T15:36:59-05:00" title="Thursday, February 16, 2012 - 15:36" class="datetime">February 16, 2012</time> </span> <div class="field field--name-field-software-link field--type-link field--label-above"> <div class="field__label">Link</div> <div class="field__items"> <div class="field__item"><a href="https://portals.broadinstitute.org/ccle/home">CCLE</a></div> </div> </div> <div class="field field--name-field-taxonomy-topic field--type-entity-reference field--label-above"> <div class="field__label">Topic</div> <div class="field__items"> <div class="field__item">cell lines</div> <div class="field__item">CCLE</div> <div class="field__item">cancer portals</div> <div class="field__item">cancer models</div> <div class="field__item">Cancer</div> <div class="field__item">cancer dependency</div> <div class="field__item">dependency map</div> <div class="field__item">cell line profiling</div> </div> </div> <div class="field field--name-field-broad-tags field--type-entity-reference field--label-above"> <div class="field__label">ӳ��ý tags</div> <div class="field__items"> <div class="field__item"><a href="/broad-tags/cancer-program" hreflang="en">Cancer Program</a></div> <div class="field__item"><a href="/broad-tags/cancer" hreflang="en">Cancer</a></div> </div> </div> Mon, 19 Sep 2022 14:53:09 +0000 kzusi@broadinstitute.org 1195701 at A tool for more accurate disease risk prediction across diverse populations /news/tool-more-accurate-disease-risk-prediction-across-diverse-populations <span class="field field--name-title field--type-string field--label-hidden">ӳ��ý-Novartis Cancer Cell Line Encyclopedia (CCLE)</span> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p> The Cancer Cell Line Encyclopedia (CCLE) project is an effort to conduct a detailed genetic characterization of a large panel of human cancer cell lines. The CCLE provides public access analysis and visualization of DNA copy number, mRNA expression, mutation data and more, for 1000 cancer cell lines. The Cancer Cell Line Encyclopedia (CCLE) project is an effort to conduct a detailed genetic characterization of a large panel of human cancer cell lines. The CCLE provides public access analysis and visualization of DNA copy number, mRNA expression, mutation data and more, for 1000 cancer cell lines.</p> <p> <span style="display:none;">cell line profiling</span></p> </div> <span class="field field--name-uid field--type-entity-reference field--label-hidden"> <span>By bistline@broadinstitute.org</span> </span> <span class="field field--name-created field--type-created field--label-hidden"><time datetime="2012-02-16T15:36:59-05:00" title="Thursday, February 16, 2012 - 15:36" class="datetime">February 16, 2012</time> </span> <div class="field field--name-field-software-link field--type-link field--label-above"> <div class="field__label">Link</div> <div class="field__items"> <div class="field__item"><a href="https://portals.broadinstitute.org/ccle/home">CCLE</a></div> </div> </div> <div class="field field--name-field-taxonomy-topic field--type-entity-reference field--label-above"> <div class="field__label">Topic</div> <div class="field__items"> <div class="field__item">cell lines</div> <div class="field__item">CCLE</div> <div class="field__item">cancer portals</div> <div class="field__item">cancer models</div> <div class="field__item">Cancer</div> <div class="field__item">cancer dependency</div> <div class="field__item">dependency map</div> <div class="field__item">cell line profiling</div> </div> </div> <div class="field field--name-field-broad-tags field--type-entity-reference field--label-above"> <div class="field__label">ӳ��ý tags</div> <div class="field__items"> <div class="field__item"><a href="/broad-tags/cancer-program" hreflang="en">Cancer Program</a></div> <div class="field__item"><a href="/broad-tags/cancer" hreflang="en">Cancer</a></div> </div> </div> Thu, 05 May 2022 18:00:00 +0000 tulrich@broadinstitute.org 1131901 at New genetic test for heart attack risk launched for patients at Mass General /news/new-genetic-test-heart-attack-risk-launched-patients-mass-general <span class="field field--name-title field--type-string field--label-hidden">ӳ��ý-Novartis Cancer Cell Line Encyclopedia (CCLE)</span> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p> The Cancer Cell Line Encyclopedia (CCLE) project is an effort to conduct a detailed genetic characterization of a large panel of human cancer cell lines. The CCLE provides public access analysis and visualization of DNA copy number, mRNA expression, mutation data and more, for 1000 cancer cell lines. The Cancer Cell Line Encyclopedia (CCLE) project is an effort to conduct a detailed genetic characterization of a large panel of human cancer cell lines. The CCLE provides public access analysis and visualization of DNA copy number, mRNA expression, mutation data and more, for 1000 cancer cell lines.</p> <p> <span style="display:none;">cell line profiling</span></p> </div> <span class="field field--name-uid field--type-entity-reference field--label-hidden"> <span>By bistline@broadinstitute.org</span> </span> <span class="field field--name-created field--type-created field--label-hidden"><time datetime="2012-02-16T15:36:59-05:00" title="Thursday, February 16, 2012 - 15:36" class="datetime">February 16, 2012</time> </span> <div class="field field--name-field-software-link field--type-link field--label-above"> <div class="field__label">Link</div> <div class="field__items"> <div class="field__item"><a href="https://portals.broadinstitute.org/ccle/home">CCLE</a></div> </div> </div> <div class="field field--name-field-taxonomy-topic field--type-entity-reference field--label-above"> <div class="field__label">Topic</div> <div class="field__items"> <div class="field__item">cell lines</div> <div class="field__item">CCLE</div> <div class="field__item">cancer portals</div> <div class="field__item">cancer models</div> <div class="field__item">Cancer</div> <div class="field__item">cancer dependency</div> <div class="field__item">dependency map</div> <div class="field__item">cell line profiling</div> </div> </div> <div class="field field--name-field-broad-tags field--type-entity-reference field--label-above"> <div class="field__label">ӳ��ý tags</div> <div class="field__items"> <div class="field__item"><a href="/broad-tags/cancer-program" hreflang="en">Cancer Program</a></div> <div class="field__item"><a href="/broad-tags/cancer" hreflang="en">Cancer</a></div> </div> </div> Wed, 27 Jan 2021 18:29:13 +0000 AnnaFiorentinoWriter 742806 at A Schizophrenia Study in Africa is Boosting Equity in Global Genetics Research /schizophrenia-study-africa-boosting-equity-global-genetics-research <span class="field field--name-title field--type-string field--label-hidden">ӳ��ý-Novartis Cancer Cell Line Encyclopedia (CCLE)</span> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p> The Cancer Cell Line Encyclopedia (CCLE) project is an effort to conduct a detailed genetic characterization of a large panel of human cancer cell lines. The CCLE provides public access analysis and visualization of DNA copy number, mRNA expression, mutation data and more, for 1000 cancer cell lines. The Cancer Cell Line Encyclopedia (CCLE) project is an effort to conduct a detailed genetic characterization of a large panel of human cancer cell lines. The CCLE provides public access analysis and visualization of DNA copy number, mRNA expression, mutation data and more, for 1000 cancer cell lines.</p> <p> <span style="display:none;">cell line profiling</span></p> </div> <span class="field field--name-uid field--type-entity-reference field--label-hidden"> <span>By bistline@broadinstitute.org</span> </span> <span class="field field--name-created field--type-created field--label-hidden"><time datetime="2012-02-16T15:36:59-05:00" title="Thursday, February 16, 2012 - 15:36" class="datetime">February 16, 2012</time> </span> <div class="field field--name-field-software-link field--type-link field--label-above"> <div class="field__label">Link</div> <div class="field__items"> <div class="field__item"><a href="https://portals.broadinstitute.org/ccle/home">CCLE</a></div> </div> </div> <div class="field field--name-field-taxonomy-topic field--type-entity-reference field--label-above"> <div class="field__label">Topic</div> <div class="field__items"> <div class="field__item">cell lines</div> <div class="field__item">CCLE</div> <div class="field__item">cancer portals</div> <div class="field__item">cancer models</div> <div class="field__item">Cancer</div> <div class="field__item">cancer dependency</div> <div class="field__item">dependency map</div> <div class="field__item">cell line profiling</div> </div> </div> <div class="field field--name-field-broad-tags field--type-entity-reference field--label-above"> <div class="field__label">ӳ��ý tags</div> <div class="field__items"> <div class="field__item"><a href="/broad-tags/cancer-program" hreflang="en">Cancer Program</a></div> <div class="field__item"><a href="/broad-tags/cancer" hreflang="en">Cancer</a></div> </div> </div> Thu, 08 Oct 2020 04:00:00 +0000 tulrich@broadinstitute.org 660191 at Genetic information can predict predisposition to rare and common blood diseases /news/genetic-information-can-predict-predisposition-rare-and-common-blood-diseases <span class="field field--name-title field--type-string field--label-hidden">ӳ��ý-Novartis Cancer Cell Line Encyclopedia (CCLE)</span> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p> The Cancer Cell Line Encyclopedia (CCLE) project is an effort to conduct a detailed genetic characterization of a large panel of human cancer cell lines. The CCLE provides public access analysis and visualization of DNA copy number, mRNA expression, mutation data and more, for 1000 cancer cell lines. The Cancer Cell Line Encyclopedia (CCLE) project is an effort to conduct a detailed genetic characterization of a large panel of human cancer cell lines. The CCLE provides public access analysis and visualization of DNA copy number, mRNA expression, mutation data and more, for 1000 cancer cell lines.</p> <p> <span style="display:none;">cell line profiling</span></p> </div> <span class="field field--name-uid field--type-entity-reference field--label-hidden"> <span>By bistline@broadinstitute.org</span> </span> <span class="field field--name-created field--type-created field--label-hidden"><time datetime="2012-02-16T15:36:59-05:00" title="Thursday, February 16, 2012 - 15:36" class="datetime">February 16, 2012</time> </span> <div class="field field--name-field-software-link field--type-link field--label-above"> <div class="field__label">Link</div> <div class="field__items"> <div class="field__item"><a href="https://portals.broadinstitute.org/ccle/home">CCLE</a></div> </div> </div> <div class="field field--name-field-taxonomy-topic field--type-entity-reference field--label-above"> <div class="field__label">Topic</div> <div class="field__items"> <div class="field__item">cell lines</div> <div class="field__item">CCLE</div> <div class="field__item">cancer portals</div> <div class="field__item">cancer models</div> <div class="field__item">Cancer</div> <div class="field__item">cancer dependency</div> <div class="field__item">dependency map</div> <div class="field__item">cell line profiling</div> </div> </div> <div class="field field--name-field-broad-tags field--type-entity-reference field--label-above"> <div class="field__label">ӳ��ý tags</div> <div class="field__items"> <div class="field__item"><a href="/broad-tags/cancer-program" hreflang="en">Cancer Program</a></div> <div class="field__item"><a href="/broad-tags/cancer" hreflang="en">Cancer</a></div> </div> </div> Thu, 03 Sep 2020 15:46:52 +0000 tulrich@broadinstitute.org 647171 at Genetic background influences disease risk from single-gene variants /news/genetic-background-influences-disease-risk-single-gene-variants <span class="field field--name-title field--type-string field--label-hidden">ӳ��ý-Novartis Cancer Cell Line Encyclopedia (CCLE)</span> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p> The Cancer Cell Line Encyclopedia (CCLE) project is an effort to conduct a detailed genetic characterization of a large panel of human cancer cell lines. The CCLE provides public access analysis and visualization of DNA copy number, mRNA expression, mutation data and more, for 1000 cancer cell lines. The Cancer Cell Line Encyclopedia (CCLE) project is an effort to conduct a detailed genetic characterization of a large panel of human cancer cell lines. The CCLE provides public access analysis and visualization of DNA copy number, mRNA expression, mutation data and more, for 1000 cancer cell lines.</p> <p> <span style="display:none;">cell line profiling</span></p> </div> <span class="field field--name-uid field--type-entity-reference field--label-hidden"> <span>By bistline@broadinstitute.org</span> </span> <span class="field field--name-created field--type-created field--label-hidden"><time datetime="2012-02-16T15:36:59-05:00" title="Thursday, February 16, 2012 - 15:36" class="datetime">February 16, 2012</time> </span> <div class="field field--name-field-software-link field--type-link field--label-above"> <div class="field__label">Link</div> <div class="field__items"> <div class="field__item"><a href="https://portals.broadinstitute.org/ccle/home">CCLE</a></div> </div> </div> <div class="field field--name-field-taxonomy-topic field--type-entity-reference field--label-above"> <div class="field__label">Topic</div> <div class="field__items"> <div class="field__item">cell lines</div> <div class="field__item">CCLE</div> <div class="field__item">cancer portals</div> <div class="field__item">cancer models</div> <div class="field__item">Cancer</div> <div class="field__item">cancer dependency</div> <div class="field__item">dependency map</div> <div class="field__item">cell line profiling</div> </div> </div> <div class="field field--name-field-broad-tags field--type-entity-reference field--label-above"> <div class="field__label">ӳ��ý tags</div> <div class="field__items"> <div class="field__item"><a href="/broad-tags/cancer-program" hreflang="en">Cancer Program</a></div> <div class="field__item"><a href="/broad-tags/cancer" hreflang="en">Cancer</a></div> </div> </div> Thu, 20 Aug 2020 13:45:30 +0000 Corie Lok 641616 at