Infectious Disease / en Sentinel program among finalists for the $100 Million 100&Change competition /news/sentinel-program-among-finalists-100-million-100change-competition <span class="field field--name-title field--type-string field--label-hidden"><h1>Sentinel program among finalists for the $100 Million 100&amp;Change competition</h1> </span> <span class="field field--name-uid field--type-entity-reference field--label-hidden"> <span>By Karen Zusi-Tran</span> </span> <span class="field field--name-created field--type-created field--label-hidden"><time datetime="2025-04-29T16:22:58-04:00" class="datetime">April 29, 2025</time> </span> <div class="hero-section container"> <div class="hero-section__row row"> <div class="hero-section__content hero-section__content_left col-6"> <div class="hero-section__breadcrumbs"> <div class="block block-system block-system-breadcrumb-block"> <nav class="breadcrumb" role="navigation" aria-labelledby="system-breadcrumb"> <h2 id="system-breadcrumb" class="visually-hidden">Breadcrumb</h2> <ol> <li> <a href="/">Home</a> </li> <li> <a href="/news">News</a> </li> </ol> </nav> </div> </div> <div class="hero-section__title"> <div class="block block-layout-builder block-field-blocknodelong-storytitle"> <span class="field field--name-title field--type-string field--label-hidden"><h1>Sentinel program among finalists for the $100 Million 100&amp;Change competition</h1> </span> </div> </div> <div class="hero-section__description"> <div class="block block-layout-builder block-field-blocknodelong-storybody"> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p>100&amp;Change is a global competition awarding a single $100 million grant to help solve one of the world's most critical social challenges.</p> </div> </div> </div> <div class="hero-section__author"> <div class="block block-layout-builder block-extra-field-blocknodelong-storyextra-field-author-custom"> By ӳý Communications </div> </div> <div class="hero-section__date"> <div class="block block-layout-builder block-field-blocknodelong-storycreated"> <span class="field field--name-created field--type-created field--label-hidden"><time datetime="2025-04-29T16:22:58-04:00" title="Tuesday, April 29, 2025 - 16:22" class="datetime">April 29, 2025</time> </span> </div> </div> </div> <div class="hero-section__right col-6"> <div class="hero-section__image"> <div class="block block-layout-builder block-field-blocknodelong-storyfield-image"> <div class="field field--name-field-image field--type-entity-reference field--label-hidden field__item"> <article class="media media--type-image media--view-mode-multiple-content-types-header"> <div class="field field--name-field-media-image field--type-image field--label-hidden field__item"> <picture> <source srcset="/files/styles/multiple_ct_header_desktop_xl/public/longstory/100Change-Finalists-vid-1920x1080-41-.png?itok=Vp_QxcgW 1x" media="all and (min-width: 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class="field__item"> <div class="paragraph paragraph--type--sidebar-articles sidebar-articles"> <div class="sidebar-articles__col"> <div class="clearfix text-formatted field field--name-field-heading field--type-text field--label-hidden field__item"><p>Related News</p> </div> <div class="field field--name-field-content-reference field--type-entity-reference field--label-hidden field__items"> <div class="field__item"><article about="/news/new-viral-surveillance-system-west-africa-showing-world-how-prevent-next-pandemic" class="node"> <div class="field field--name-field-image field--type-entity-reference field--label-hidden field__item"><article class="media media--type-image media--view-mode-multiple-ct-sidebar-link-with-image"> <div class="field field--name-field-media-image field--type-image field--label-hidden field__item"> <a href="/news/new-viral-surveillance-system-west-africa-showing-world-how-prevent-next-pandemic"><picture> <source 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srcset="/files/styles/multiple_ct_sidebar_link_with_image_tablet/public/longstory/7F5A5285%20%281%29.JPG?itok=vS0v4syD 1x" media="all and (min-width: 540px) and (max-width: 799px)" type="image/jpeg" width="285" height="186"> <source srcset="/files/styles/multiple_ct_sidebar_link_with_image_phone/public/longstory/7F5A5285%20%281%29.JPG?itok=uvaL-P0e 1x" media="all and (max-width: 539px)" type="image/jpeg" width="220" height="186"> <img loading="eager" width="220" height="186" src="/files/styles/multiple_ct_sidebar_link_with_image_phone/public/longstory/7F5A5285%20%281%29.JPG?itok=uvaL-P0e" alt="Christian Happi and Pardis Sabeti stand outside Redeemer's University" title="Christian Happi and Pardis Sabeti stand outside Redeemer's University" typeof="foaf:Image"> </picture></a> </div> </article> </div> <div class="node__content"> <a href="/news/new-viral-surveillance-system-west-africa-showing-world-how-prevent-next-pandemic" class="node__title"><span class="field field--name-title field--type-string field--label-hidden">A new viral surveillance system in West Africa is showing the world how to prevent the next pandemic</span> </a> </div> </article> </div> <div class="field__item"><article about="/news/scientific-coalition-developing-surveillance-system-detecting-emerging-pandemics-real-time" class="node"> <div class="field field--name-field-image field--type-entity-reference field--label-hidden field__item"><article class="media media--type-image media--view-mode-multiple-ct-sidebar-link-with-image"> <div class="field field--name-field-media-image field--type-image field--label-hidden field__item"> <a href="/news/scientific-coalition-developing-surveillance-system-detecting-emerging-pandemics-real-time"><picture> <source srcset="/files/styles/multiple_ct_sidebar_link_with_image_desktop_xl/public/news/images/2020/Sentinel-main-1%20%281%29_0.jpg?h=d3e04ee7&amp;itok=cH_Pghq8 1x" media="all and (min-width: 1921px)" type="image/jpeg" width="104" height="104"> <source 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(max-width: 799px)" type="image/jpeg" width="285" height="186"> <source srcset="/files/styles/multiple_ct_sidebar_link_with_image_phone/public/news/images/2020/Sentinel-main-1%20%281%29_0.jpg?h=d3e04ee7&amp;itok=g6wJU_LZ 1x" media="all and (max-width: 539px)" type="image/jpeg" width="220" height="186"> <img loading="eager" width="220" height="186" src="/files/styles/multiple_ct_sidebar_link_with_image_phone/public/news/images/2020/Sentinel-main-1%20%281%29_0.jpg?h=d3e04ee7&amp;itok=g6wJU_LZ" alt typeof="foaf:Image"> </picture></a> </div> </article> </div> <div class="node__content"> <a href="/news/scientific-coalition-developing-surveillance-system-detecting-emerging-pandemics-real-time" class="node__title"><span class="field field--name-title field--type-string field--label-hidden">Scientific coalition developing surveillance system for detecting emerging pandemics in real-time</span> </a> </div> </article> </div> </div> </div> </div> </div> </div> <div class="clearfix text-formatted field field--name-field-text field--type-text-long field--label-hidden field__item"><p>The MacArthur Foundation and its nonprofit affiliate, Lever for Change, have announced the <a href="https://www.sentinelpandemicprevention.org/">Sentinel program</a> as one of five finalists in the 100&amp;Change competition.</p> <p>100&amp;Change is a global competition awarding a single $100 million grant to help solve one of the world's most critical social challenges. The competition has influenced the philanthropic sector by encouraging funders to adopt large-scale, collaborative approaches to problem-solving.</p> <p>The Sentinel program, led by <a href="/bios/pardis-sabeti">Pardis Sabeti</a> at the ӳý and <a href="https://staff.run.edu.ng/process.php?qp=RUN%2FREG%2FSS%2FPF%2F536&amp;active=vprofile">Christian Happi</a> at the Institute for Genomics and Global Health (IGH) at Redeemer’s University, Nigeria, is a pandemic prevention system that deploys cutting-edge genomic and data technologies to empower communities to stop epidemics through pathogen surveillance and outbreak response. Launched in 2020 thanks to support from Flu Lab and a cohort of generous donors through TED’s Audacious Project, including the ELMA Foundation, MacKenzie Scott, the Skoll Foundation, and Open Philanthropy, it was piloted in West Africa where it has already had a huge impact, helping frontline workers respond to COVID-19, mpox, Marburg, Ebola, and Lassa fever.</p> <p>“We say ‘detect, connect, and empower,’” explained Sabeti. “Detect any pathogen anywhere around the world, connect that information so it can be shared and acted upon, and empower every actor in the system — every frontline worker, every citizen&nbsp; — to work collectively towards stopping outbreaks from spreading.”</p> <p>Sentinel aims to transform outbreak detection and response in Africa and around the world by training thousands of health workers, achieving national-scale disease surveillance programs, and enabling rapid outbreak detection and response scale-up, thereby profoundly impacting millions of lives and strengthening global health security.</p> <p>“We are at a critical inflection point in our ability to prepare for and respond to future deadly epidemic and pandemic threats,” said Happi. “The Sentinel program will help build a resilient infectious disease surveillance response network, codify and scale our training programs for local scientists and public health workers, and ensure sustainable outbreak response capacity throughout Africa and across the world.”<br> &nbsp;</p> <p><iframe allow="accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share" allowfullscreen frameborder="0" height="315" src="https://www.youtube.com/embed/OSekY1gppLE?si=SwDrJa-6DAD-ehot" title="YouTube video player" width="560"></iframe></p> <p>&nbsp;<br> “Now is the time to dream big, collaborate deeply, and develop new solutions to change the world,” said MacArthur President John Palfrey. “Our 100&amp;Change finalists want to scale ambitious ideas that will help millions of people. Today, we hope the sector finds inspiration in these important projects and joins us in celebrating this milestone in the competition.”</p> <p>100&amp;Change received more than 800 applications from organizations and collaborations worldwide, with each proposal identifying a problem and presenting a compelling solution that is impactful, evidence-based, feasible, durable, and just. The <a href="https://www.100andchange.org/results/finalists">selected finalists</a> represent transformative projects that have the potential to drive meaningful change on a global scale.</p> <p>The final award recipient will be selected by MacArthur’s Board of Directors and announced later this year.</p> </div> </div> </div> </div> </div> </div> </div> <div class="content-section container"> <div class="content-section__main"> <div class="block-node-broad-tags block block-layout-builder block-field-blocknodelong-storyfield-broad-tags"> <div class="block-node-broad-tags__row"> <div class="block-node-broad-tags__title">Tags:</div> <div class="field field--name-field-broad-tags field--type-entity-reference field--label-hidden field__items"> <div class="field__item"><a href="/broad-tags/infectious-disease-and-microbiome-0" hreflang="en">Infectious Disease and Microbiome Program</a></div> <div class="field__item"><a href="/broad-tags/infectious-disease" hreflang="en">Infectious Disease</a></div> <div class="field__item"><a href="/broad-tags/pardis-sabeti" hreflang="en">Pardis Sabeti</a></div> </div> </div> </div> </div> </div> Tue, 29 Apr 2025 20:22:58 +0000 kzusi@broadinstitute.org 5558516 at Simple test for flu could improve diagnosis and surveillance /news/simple-test-flu-could-improve-diagnosis-and-surveillance <span class="field field--name-title field--type-string field--label-hidden"><h1>Sentinel program among finalists for the $100 Million 100&amp;Change competition</h1> </span> <span class="field field--name-uid field--type-entity-reference field--label-hidden"> <span>By Karen Zusi-Tran</span> </span> <span class="field field--name-created field--type-created field--label-hidden"><time datetime="2025-04-29T16:22:58-04:00" class="datetime">April 29, 2025</time> </span> <div class="hero-section container"> <div class="hero-section__row row"> <div class="hero-section__content hero-section__content_left col-6"> <div class="hero-section__breadcrumbs"> <div class="block block-system block-system-breadcrumb-block"> <nav class="breadcrumb" role="navigation" aria-labelledby="system-breadcrumb"> <h2 id="system-breadcrumb" class="visually-hidden">Breadcrumb</h2> <ol> <li> <a href="/">Home</a> </li> <li> <a href="/news">News</a> </li> </ol> </nav> </div> </div> <div class="hero-section__title"> <div class="block block-layout-builder block-field-blocknodelong-storytitle"> <span class="field field--name-title field--type-string field--label-hidden"><h1>Sentinel program among finalists for the $100 Million 100&amp;Change competition</h1> </span> </div> </div> <div class="hero-section__description"> <div class="block block-layout-builder block-field-blocknodelong-storybody"> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p>100&amp;Change is a global competition awarding a single $100 million grant to help solve one of the world's most critical social challenges.</p> </div> </div> </div> <div class="hero-section__author"> <div class="block block-layout-builder block-extra-field-blocknodelong-storyextra-field-author-custom"> By ӳý Communications </div> </div> <div class="hero-section__date"> <div class="block block-layout-builder block-field-blocknodelong-storycreated"> <span class="field field--name-created field--type-created field--label-hidden"><time datetime="2025-04-29T16:22:58-04:00" title="Tuesday, April 29, 2025 - 16:22" class="datetime">April 29, 2025</time> </span> </div> </div> </div> <div class="hero-section__right col-6"> <div class="hero-section__image"> <div class="block block-layout-builder block-field-blocknodelong-storyfield-image"> <div class="field field--name-field-image field--type-entity-reference field--label-hidden field__item"> <article class="media media--type-image media--view-mode-multiple-content-types-header"> <div class="field field--name-field-media-image field--type-image field--label-hidden field__item"> <picture> <source srcset="/files/styles/multiple_ct_header_desktop_xl/public/longstory/100Change-Finalists-vid-1920x1080-41-.png?itok=Vp_QxcgW 1x" media="all and (min-width: 1921px)" type="image/png" width="754" height="503"> <source srcset="/files/styles/multiple_ct_header_desktop_xl/public/longstory/100Change-Finalists-vid-1920x1080-41-.png?itok=Vp_QxcgW 1x" media="all and (min-width: 1601px) and (max-width: 1920px)" type="image/png" width="754" height="503"> <source srcset="/files/styles/multiple_ct_header_desktop/public/longstory/100Change-Finalists-vid-1920x1080-41-.png?itok=Zjsyo6YF 1x" media="all and (min-width: 1340px) and (max-width: 1600px)" type="image/png" width="736" height="520"> <source srcset="/files/styles/multiple_ct_header_laptop/public/longstory/100Change-Finalists-vid-1920x1080-41-.png?itok=MLGnAHQL 1x" media="all and (min-width: 800px) and (max-width: 1339px)" type="image/png" width="641" height="451"> <source srcset="/files/styles/multiple_ct_header_tablet/public/longstory/100Change-Finalists-vid-1920x1080-41-.png?itok=iJ44u04g 1x" media="all and (min-width: 540px) and (max-width: 799px)" type="image/png" width="706" height="417"> <source srcset="/files/styles/multiple_ct_header_phone/public/longstory/100Change-Finalists-vid-1920x1080-41-.png?itok=ZApvucFb 1x" media="all and (max-width: 539px)" type="image/png" width="499" height="294"> <img loading="eager" width="499" height="294" src="/files/styles/multiple_ct_header_phone/public/longstory/100Change-Finalists-vid-1920x1080-41-.png?itok=ZApvucFb" alt="Sentinel program among finalists for the $100 Million 100&amp;Change competition." title="Sentinel program among finalists for the $100 Million 100&amp;Change competition." typeof="foaf:Image"> </picture> </div> <div class="media-caption"> <div class="media-caption__description"> Sentinel program among finalists for the $100 Million 100&amp;Change competition. </div> </div> </article> </div> 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(max-width: 1339px)" type="image/jpeg" width="87" height="104"> <source srcset="/files/styles/multiple_ct_sidebar_link_with_image_tablet/public/longstory/7F5A5285%20%281%29.JPG?itok=vS0v4syD 1x" media="all and (min-width: 540px) and (max-width: 799px)" type="image/jpeg" width="285" height="186"> <source srcset="/files/styles/multiple_ct_sidebar_link_with_image_phone/public/longstory/7F5A5285%20%281%29.JPG?itok=uvaL-P0e 1x" media="all and (max-width: 539px)" type="image/jpeg" width="220" height="186"> <img loading="eager" width="220" height="186" src="/files/styles/multiple_ct_sidebar_link_with_image_phone/public/longstory/7F5A5285%20%281%29.JPG?itok=uvaL-P0e" alt="Christian Happi and Pardis Sabeti stand outside Redeemer's University" title="Christian Happi and Pardis Sabeti stand outside Redeemer's University" typeof="foaf:Image"> </picture></a> </div> </article> </div> <div class="node__content"> <a href="/news/new-viral-surveillance-system-west-africa-showing-world-how-prevent-next-pandemic" class="node__title"><span class="field field--name-title field--type-string field--label-hidden">A new viral surveillance system in West Africa is showing the world how to prevent the next pandemic</span> </a> </div> </article> </div> <div class="field__item"><article about="/news/scientific-coalition-developing-surveillance-system-detecting-emerging-pandemics-real-time" class="node"> <div class="field field--name-field-image field--type-entity-reference field--label-hidden field__item"><article class="media media--type-image media--view-mode-multiple-ct-sidebar-link-with-image"> <div class="field field--name-field-media-image field--type-image field--label-hidden field__item"> <a href="/news/scientific-coalition-developing-surveillance-system-detecting-emerging-pandemics-real-time"><picture> <source srcset="/files/styles/multiple_ct_sidebar_link_with_image_desktop_xl/public/news/images/2020/Sentinel-main-1%20%281%29_0.jpg?h=d3e04ee7&amp;itok=cH_Pghq8 1x" media="all and (min-width: 1921px)" type="image/jpeg" width="104" height="104"> <source srcset="/files/styles/multiple_ct_sidebar_link_with_image_desktop_xl/public/news/images/2020/Sentinel-main-1%20%281%29_0.jpg?h=d3e04ee7&amp;itok=cH_Pghq8 1x" media="all and (min-width: 1601px) and (max-width: 1920px)" type="image/jpeg" width="104" height="104"> <source srcset="/files/styles/multiple_ct_sidebar_link_with_image_desktop/public/news/images/2020/Sentinel-main-1%20%281%29_0.jpg?h=d3e04ee7&amp;itok=cbSnF6TK 1x" media="all and (min-width: 1340px) and (max-width: 1600px)" type="image/jpeg" width="87" height="104"> <source srcset="/files/styles/multiple_ct_sidebar_link_with_image_desktop/public/news/images/2020/Sentinel-main-1%20%281%29_0.jpg?h=d3e04ee7&amp;itok=cbSnF6TK 1x" media="all and (min-width: 800px) and (max-width: 1339px)" type="image/jpeg" width="87" height="104"> <source srcset="/files/styles/multiple_ct_sidebar_link_with_image_tablet/public/news/images/2020/Sentinel-main-1%20%281%29_0.jpg?h=d3e04ee7&amp;itok=1y7ORLrC 1x" media="all and (min-width: 540px) and (max-width: 799px)" type="image/jpeg" width="285" height="186"> <source srcset="/files/styles/multiple_ct_sidebar_link_with_image_phone/public/news/images/2020/Sentinel-main-1%20%281%29_0.jpg?h=d3e04ee7&amp;itok=g6wJU_LZ 1x" media="all and (max-width: 539px)" type="image/jpeg" width="220" height="186"> <img loading="eager" width="220" height="186" src="/files/styles/multiple_ct_sidebar_link_with_image_phone/public/news/images/2020/Sentinel-main-1%20%281%29_0.jpg?h=d3e04ee7&amp;itok=g6wJU_LZ" alt typeof="foaf:Image"> </picture></a> </div> </article> </div> <div class="node__content"> <a href="/news/scientific-coalition-developing-surveillance-system-detecting-emerging-pandemics-real-time" class="node__title"><span class="field field--name-title field--type-string field--label-hidden">Scientific coalition developing surveillance system for detecting emerging pandemics in real-time</span> </a> </div> </article> </div> </div> </div> </div> </div> </div> <div class="clearfix text-formatted field field--name-field-text field--type-text-long field--label-hidden field__item"><p>The MacArthur Foundation and its nonprofit affiliate, Lever for Change, have announced the <a href="https://www.sentinelpandemicprevention.org/">Sentinel program</a> as one of five finalists in the 100&amp;Change competition.</p> <p>100&amp;Change is a global competition awarding a single $100 million grant to help solve one of the world's most critical social challenges. The competition has influenced the philanthropic sector by encouraging funders to adopt large-scale, collaborative approaches to problem-solving.</p> <p>The Sentinel program, led by <a href="/bios/pardis-sabeti">Pardis Sabeti</a> at the ӳý and <a href="https://staff.run.edu.ng/process.php?qp=RUN%2FREG%2FSS%2FPF%2F536&amp;active=vprofile">Christian Happi</a> at the Institute for Genomics and Global Health (IGH) at Redeemer’s University, Nigeria, is a pandemic prevention system that deploys cutting-edge genomic and data technologies to empower communities to stop epidemics through pathogen surveillance and outbreak response. Launched in 2020 thanks to support from Flu Lab and a cohort of generous donors through TED’s Audacious Project, including the ELMA Foundation, MacKenzie Scott, the Skoll Foundation, and Open Philanthropy, it was piloted in West Africa where it has already had a huge impact, helping frontline workers respond to COVID-19, mpox, Marburg, Ebola, and Lassa fever.</p> <p>“We say ‘detect, connect, and empower,’” explained Sabeti. “Detect any pathogen anywhere around the world, connect that information so it can be shared and acted upon, and empower every actor in the system — every frontline worker, every citizen&nbsp; — to work collectively towards stopping outbreaks from spreading.”</p> <p>Sentinel aims to transform outbreak detection and response in Africa and around the world by training thousands of health workers, achieving national-scale disease surveillance programs, and enabling rapid outbreak detection and response scale-up, thereby profoundly impacting millions of lives and strengthening global health security.</p> <p>“We are at a critical inflection point in our ability to prepare for and respond to future deadly epidemic and pandemic threats,” said Happi. “The Sentinel program will help build a resilient infectious disease surveillance response network, codify and scale our training programs for local scientists and public health workers, and ensure sustainable outbreak response capacity throughout Africa and across the world.”<br> &nbsp;</p> <p><iframe allow="accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share" allowfullscreen frameborder="0" height="315" src="https://www.youtube.com/embed/OSekY1gppLE?si=SwDrJa-6DAD-ehot" title="YouTube video player" width="560"></iframe></p> <p>&nbsp;<br> “Now is the time to dream big, collaborate deeply, and develop new solutions to change the world,” said MacArthur President John Palfrey. “Our 100&amp;Change finalists want to scale ambitious ideas that will help millions of people. Today, we hope the sector finds inspiration in these important projects and joins us in celebrating this milestone in the competition.”</p> <p>100&amp;Change received more than 800 applications from organizations and collaborations worldwide, with each proposal identifying a problem and presenting a compelling solution that is impactful, evidence-based, feasible, durable, and just. The <a href="https://www.100andchange.org/results/finalists">selected finalists</a> represent transformative projects that have the potential to drive meaningful change on a global scale.</p> <p>The final award recipient will be selected by MacArthur’s Board of Directors and announced later this year.</p> </div> </div> </div> </div> </div> </div> </div> <div class="content-section container"> <div class="content-section__main"> <div class="block-node-broad-tags block block-layout-builder block-field-blocknodelong-storyfield-broad-tags"> <div class="block-node-broad-tags__row"> <div class="block-node-broad-tags__title">Tags:</div> <div class="field field--name-field-broad-tags field--type-entity-reference field--label-hidden field__items"> <div class="field__item"><a href="/broad-tags/infectious-disease-and-microbiome-0" hreflang="en">Infectious Disease and Microbiome Program</a></div> <div class="field__item"><a href="/broad-tags/infectious-disease" hreflang="en">Infectious Disease</a></div> <div class="field__item"><a href="/broad-tags/pardis-sabeti" hreflang="en">Pardis Sabeti</a></div> </div> </div> </div> </div> </div> Tue, 18 Jun 2024 15:00:00 +0000 adicorat 5557056 at A new viral surveillance system in West Africa is showing the world how to prevent the next pandemic /news/new-viral-surveillance-system-west-africa-showing-world-how-prevent-next-pandemic <span class="field field--name-title field--type-string field--label-hidden"><h1>Sentinel program among finalists for the $100 Million 100&amp;Change competition</h1> </span> <span class="field field--name-uid field--type-entity-reference field--label-hidden"> <span>By Karen Zusi-Tran</span> </span> <span class="field field--name-created field--type-created field--label-hidden"><time datetime="2025-04-29T16:22:58-04:00" class="datetime">April 29, 2025</time> </span> <div class="hero-section container"> <div class="hero-section__row row"> <div class="hero-section__content hero-section__content_left col-6"> <div class="hero-section__breadcrumbs"> <div class="block block-system block-system-breadcrumb-block"> <nav class="breadcrumb" role="navigation" aria-labelledby="system-breadcrumb"> <h2 id="system-breadcrumb" class="visually-hidden">Breadcrumb</h2> <ol> <li> <a href="/">Home</a> </li> <li> <a href="/news">News</a> </li> </ol> </nav> </div> </div> <div class="hero-section__title"> <div class="block block-layout-builder block-field-blocknodelong-storytitle"> <span class="field field--name-title field--type-string field--label-hidden"><h1>Sentinel program among finalists for the $100 Million 100&amp;Change competition</h1> </span> </div> </div> <div class="hero-section__description"> <div class="block block-layout-builder block-field-blocknodelong-storybody"> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p>100&amp;Change is a global competition awarding a single $100 million grant to help solve one of the world's most critical social challenges.</p> </div> </div> </div> <div class="hero-section__author"> <div class="block block-layout-builder block-extra-field-blocknodelong-storyextra-field-author-custom"> By ӳý Communications </div> </div> <div class="hero-section__date"> <div class="block block-layout-builder block-field-blocknodelong-storycreated"> <span class="field field--name-created field--type-created field--label-hidden"><time datetime="2025-04-29T16:22:58-04:00" title="Tuesday, April 29, 2025 - 16:22" class="datetime">April 29, 2025</time> </span> </div> </div> </div> <div class="hero-section__right col-6"> <div class="hero-section__image"> <div class="block block-layout-builder block-field-blocknodelong-storyfield-image"> <div class="field field--name-field-image field--type-entity-reference field--label-hidden field__item"> <article class="media media--type-image media--view-mode-multiple-content-types-header"> <div class="field field--name-field-media-image field--type-image field--label-hidden field__item"> <picture> <source srcset="/files/styles/multiple_ct_header_desktop_xl/public/longstory/100Change-Finalists-vid-1920x1080-41-.png?itok=Vp_QxcgW 1x" media="all and (min-width: 1921px)" type="image/png" width="754" height="503"> <source srcset="/files/styles/multiple_ct_header_desktop_xl/public/longstory/100Change-Finalists-vid-1920x1080-41-.png?itok=Vp_QxcgW 1x" media="all and (min-width: 1601px) and (max-width: 1920px)" type="image/png" width="754" height="503"> <source srcset="/files/styles/multiple_ct_header_desktop/public/longstory/100Change-Finalists-vid-1920x1080-41-.png?itok=Zjsyo6YF 1x" media="all and (min-width: 1340px) and (max-width: 1600px)" type="image/png" width="736" height="520"> <source srcset="/files/styles/multiple_ct_header_laptop/public/longstory/100Change-Finalists-vid-1920x1080-41-.png?itok=MLGnAHQL 1x" media="all and (min-width: 800px) and (max-width: 1339px)" type="image/png" width="641" height="451"> <source srcset="/files/styles/multiple_ct_header_tablet/public/longstory/100Change-Finalists-vid-1920x1080-41-.png?itok=iJ44u04g 1x" media="all and (min-width: 540px) and (max-width: 799px)" type="image/png" width="706" height="417"> <source srcset="/files/styles/multiple_ct_header_phone/public/longstory/100Change-Finalists-vid-1920x1080-41-.png?itok=ZApvucFb 1x" media="all and (max-width: 539px)" type="image/png" width="499" height="294"> <img loading="eager" width="499" height="294" src="/files/styles/multiple_ct_header_phone/public/longstory/100Change-Finalists-vid-1920x1080-41-.png?itok=ZApvucFb" alt="Sentinel program among finalists for the $100 Million 100&amp;Change competition." title="Sentinel program among finalists for the $100 Million 100&amp;Change competition." typeof="foaf:Image"> </picture> </div> <div class="media-caption"> <div class="media-caption__description"> Sentinel program among finalists for the $100 Million 100&amp;Change competition. </div> </div> </article> </div> 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(max-width: 1339px)" type="image/jpeg" width="87" height="104"> <source srcset="/files/styles/multiple_ct_sidebar_link_with_image_tablet/public/longstory/7F5A5285%20%281%29.JPG?itok=vS0v4syD 1x" media="all and (min-width: 540px) and (max-width: 799px)" type="image/jpeg" width="285" height="186"> <source srcset="/files/styles/multiple_ct_sidebar_link_with_image_phone/public/longstory/7F5A5285%20%281%29.JPG?itok=uvaL-P0e 1x" media="all and (max-width: 539px)" type="image/jpeg" width="220" height="186"> <img loading="eager" width="220" height="186" src="/files/styles/multiple_ct_sidebar_link_with_image_phone/public/longstory/7F5A5285%20%281%29.JPG?itok=uvaL-P0e" alt="Christian Happi and Pardis Sabeti stand outside Redeemer's University" title="Christian Happi and Pardis Sabeti stand outside Redeemer's University" typeof="foaf:Image"> </picture></a> </div> </article> </div> <div class="node__content"> <a href="/news/new-viral-surveillance-system-west-africa-showing-world-how-prevent-next-pandemic" class="node__title"><span class="field field--name-title field--type-string field--label-hidden">A new viral surveillance system in West Africa is showing the world how to prevent the next pandemic</span> </a> </div> </article> </div> <div class="field__item"><article about="/news/scientific-coalition-developing-surveillance-system-detecting-emerging-pandemics-real-time" class="node"> <div class="field field--name-field-image field--type-entity-reference field--label-hidden field__item"><article class="media media--type-image media--view-mode-multiple-ct-sidebar-link-with-image"> <div class="field field--name-field-media-image field--type-image field--label-hidden field__item"> <a href="/news/scientific-coalition-developing-surveillance-system-detecting-emerging-pandemics-real-time"><picture> <source 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type="image/jpeg" width="87" height="104"> <source srcset="/files/styles/multiple_ct_sidebar_link_with_image_tablet/public/news/images/2020/Sentinel-main-1%20%281%29_0.jpg?h=d3e04ee7&amp;itok=1y7ORLrC 1x" media="all and (min-width: 540px) and (max-width: 799px)" type="image/jpeg" width="285" height="186"> <source srcset="/files/styles/multiple_ct_sidebar_link_with_image_phone/public/news/images/2020/Sentinel-main-1%20%281%29_0.jpg?h=d3e04ee7&amp;itok=g6wJU_LZ 1x" media="all and (max-width: 539px)" type="image/jpeg" width="220" height="186"> <img loading="eager" width="220" height="186" src="/files/styles/multiple_ct_sidebar_link_with_image_phone/public/news/images/2020/Sentinel-main-1%20%281%29_0.jpg?h=d3e04ee7&amp;itok=g6wJU_LZ" alt typeof="foaf:Image"> </picture></a> </div> </article> </div> <div class="node__content"> <a href="/news/scientific-coalition-developing-surveillance-system-detecting-emerging-pandemics-real-time" class="node__title"><span class="field field--name-title field--type-string field--label-hidden">Scientific coalition developing surveillance system for detecting emerging pandemics in real-time</span> </a> </div> </article> </div> </div> </div> </div> </div> </div> <div class="clearfix text-formatted field field--name-field-text field--type-text-long field--label-hidden field__item"><p>The MacArthur Foundation and its nonprofit affiliate, Lever for Change, have announced the <a href="https://www.sentinelpandemicprevention.org/">Sentinel program</a> as one of five finalists in the 100&amp;Change competition.</p> <p>100&amp;Change is a global competition awarding a single $100 million grant to help solve one of the world's most critical social challenges. The competition has influenced the philanthropic sector by encouraging funders to adopt large-scale, collaborative approaches to problem-solving.</p> <p>The Sentinel program, led by <a href="/bios/pardis-sabeti">Pardis Sabeti</a> at the ӳý and <a href="https://staff.run.edu.ng/process.php?qp=RUN%2FREG%2FSS%2FPF%2F536&amp;active=vprofile">Christian Happi</a> at the Institute for Genomics and Global Health (IGH) at Redeemer’s University, Nigeria, is a pandemic prevention system that deploys cutting-edge genomic and data technologies to empower communities to stop epidemics through pathogen surveillance and outbreak response. Launched in 2020 thanks to support from Flu Lab and a cohort of generous donors through TED’s Audacious Project, including the ELMA Foundation, MacKenzie Scott, the Skoll Foundation, and Open Philanthropy, it was piloted in West Africa where it has already had a huge impact, helping frontline workers respond to COVID-19, mpox, Marburg, Ebola, and Lassa fever.</p> <p>“We say ‘detect, connect, and empower,’” explained Sabeti. “Detect any pathogen anywhere around the world, connect that information so it can be shared and acted upon, and empower every actor in the system — every frontline worker, every citizen&nbsp; — to work collectively towards stopping outbreaks from spreading.”</p> <p>Sentinel aims to transform outbreak detection and response in Africa and around the world by training thousands of health workers, achieving national-scale disease surveillance programs, and enabling rapid outbreak detection and response scale-up, thereby profoundly impacting millions of lives and strengthening global health security.</p> <p>“We are at a critical inflection point in our ability to prepare for and respond to future deadly epidemic and pandemic threats,” said Happi. “The Sentinel program will help build a resilient infectious disease surveillance response network, codify and scale our training programs for local scientists and public health workers, and ensure sustainable outbreak response capacity throughout Africa and across the world.”<br> &nbsp;</p> <p><iframe allow="accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share" allowfullscreen frameborder="0" height="315" src="https://www.youtube.com/embed/OSekY1gppLE?si=SwDrJa-6DAD-ehot" title="YouTube video player" width="560"></iframe></p> <p>&nbsp;<br> “Now is the time to dream big, collaborate deeply, and develop new solutions to change the world,” said MacArthur President John Palfrey. “Our 100&amp;Change finalists want to scale ambitious ideas that will help millions of people. Today, we hope the sector finds inspiration in these important projects and joins us in celebrating this milestone in the competition.”</p> <p>100&amp;Change received more than 800 applications from organizations and collaborations worldwide, with each proposal identifying a problem and presenting a compelling solution that is impactful, evidence-based, feasible, durable, and just. The <a href="https://www.100andchange.org/results/finalists">selected finalists</a> represent transformative projects that have the potential to drive meaningful change on a global scale.</p> <p>The final award recipient will be selected by MacArthur’s Board of Directors and announced later this year.</p> </div> </div> </div> </div> </div> </div> </div> <div class="content-section container"> <div class="content-section__main"> <div class="block-node-broad-tags block block-layout-builder block-field-blocknodelong-storyfield-broad-tags"> <div class="block-node-broad-tags__row"> <div class="block-node-broad-tags__title">Tags:</div> <div class="field field--name-field-broad-tags field--type-entity-reference field--label-hidden field__items"> <div class="field__item"><a href="/broad-tags/infectious-disease-and-microbiome-0" hreflang="en">Infectious Disease and Microbiome Program</a></div> <div class="field__item"><a href="/broad-tags/infectious-disease" hreflang="en">Infectious Disease</a></div> <div class="field__item"><a href="/broad-tags/pardis-sabeti" hreflang="en">Pardis Sabeti</a></div> </div> </div> </div> </div> </div> Thu, 25 Apr 2024 15:00:00 +0000 adicorat 5556791 at A close research partnership with African scientists helps solve the mystery of malaria-like illnesses /news/close-research-partnership-african-scientists-helps-solve-mystery-malaria-illnesses <span class="field field--name-title field--type-string field--label-hidden"><h1>Sentinel program among finalists for the $100 Million 100&amp;Change competition</h1> </span> <span class="field field--name-uid field--type-entity-reference field--label-hidden"> <span>By Karen Zusi-Tran</span> </span> <span class="field field--name-created field--type-created field--label-hidden"><time datetime="2025-04-29T16:22:58-04:00" class="datetime">April 29, 2025</time> </span> <div class="hero-section container"> <div class="hero-section__row row"> <div class="hero-section__content hero-section__content_left col-6"> <div class="hero-section__breadcrumbs"> <div class="block block-system block-system-breadcrumb-block"> <nav class="breadcrumb" role="navigation" aria-labelledby="system-breadcrumb"> <h2 id="system-breadcrumb" class="visually-hidden">Breadcrumb</h2> <ol> <li> <a href="/">Home</a> </li> <li> <a href="/news">News</a> </li> </ol> </nav> </div> </div> <div class="hero-section__title"> <div class="block block-layout-builder block-field-blocknodelong-storytitle"> <span class="field field--name-title field--type-string field--label-hidden"><h1>Sentinel program among finalists for the $100 Million 100&amp;Change competition</h1> </span> </div> </div> <div class="hero-section__description"> <div class="block block-layout-builder block-field-blocknodelong-storybody"> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p>100&amp;Change is a global competition awarding a single $100 million grant to help solve one of the world's most critical social challenges.</p> </div> </div> </div> <div class="hero-section__author"> <div class="block block-layout-builder block-extra-field-blocknodelong-storyextra-field-author-custom"> By ӳý Communications </div> </div> <div class="hero-section__date"> <div class="block block-layout-builder block-field-blocknodelong-storycreated"> <span class="field field--name-created field--type-created field--label-hidden"><time datetime="2025-04-29T16:22:58-04:00" title="Tuesday, April 29, 2025 - 16:22" class="datetime">April 29, 2025</time> </span> </div> </div> </div> <div class="hero-section__right col-6"> <div class="hero-section__image"> <div class="block block-layout-builder block-field-blocknodelong-storyfield-image"> <div class="field field--name-field-image field--type-entity-reference field--label-hidden field__item"> <article class="media media--type-image media--view-mode-multiple-content-types-header"> <div class="field field--name-field-media-image field--type-image field--label-hidden field__item"> <picture> <source srcset="/files/styles/multiple_ct_header_desktop_xl/public/longstory/100Change-Finalists-vid-1920x1080-41-.png?itok=Vp_QxcgW 1x" media="all and (min-width: 1921px)" type="image/png" width="754" height="503"> <source srcset="/files/styles/multiple_ct_header_desktop_xl/public/longstory/100Change-Finalists-vid-1920x1080-41-.png?itok=Vp_QxcgW 1x" media="all and (min-width: 1601px) and (max-width: 1920px)" type="image/png" width="754" height="503"> <source srcset="/files/styles/multiple_ct_header_desktop/public/longstory/100Change-Finalists-vid-1920x1080-41-.png?itok=Zjsyo6YF 1x" media="all and (min-width: 1340px) and (max-width: 1600px)" type="image/png" width="736" height="520"> <source srcset="/files/styles/multiple_ct_header_laptop/public/longstory/100Change-Finalists-vid-1920x1080-41-.png?itok=MLGnAHQL 1x" media="all and (min-width: 800px) and (max-width: 1339px)" type="image/png" width="641" height="451"> <source srcset="/files/styles/multiple_ct_header_tablet/public/longstory/100Change-Finalists-vid-1920x1080-41-.png?itok=iJ44u04g 1x" media="all and (min-width: 540px) and (max-width: 799px)" type="image/png" width="706" height="417"> <source srcset="/files/styles/multiple_ct_header_phone/public/longstory/100Change-Finalists-vid-1920x1080-41-.png?itok=ZApvucFb 1x" media="all and (max-width: 539px)" type="image/png" width="499" height="294"> <img loading="eager" width="499" height="294" src="/files/styles/multiple_ct_header_phone/public/longstory/100Change-Finalists-vid-1920x1080-41-.png?itok=ZApvucFb" alt="Sentinel program among finalists for the $100 Million 100&amp;Change competition." title="Sentinel program among finalists for the $100 Million 100&amp;Change competition." typeof="foaf:Image"> </picture> </div> <div class="media-caption"> <div class="media-caption__description"> Sentinel program among finalists for the $100 Million 100&amp;Change 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field--label-hidden field__items"> <div class="field__item"> <div class="paragraph paragraph--type--text-with-sidebar text-with-sidebar"> <div class="field field--name-field-sidebar field--type-entity-reference-revisions field--label-hidden field__items"> <div class="field__item"> <div class="paragraph paragraph--type--sidebar-articles sidebar-articles"> <div class="sidebar-articles__col"> <div class="clearfix text-formatted field field--name-field-heading field--type-text field--label-hidden field__item"><p>Related News</p> </div> <div class="field field--name-field-content-reference field--type-entity-reference field--label-hidden field__items"> <div class="field__item"><article about="/news/new-viral-surveillance-system-west-africa-showing-world-how-prevent-next-pandemic" class="node"> <div class="field field--name-field-image field--type-entity-reference field--label-hidden field__item"><article class="media media--type-image media--view-mode-multiple-ct-sidebar-link-with-image"> <div class="field field--name-field-media-image field--type-image field--label-hidden field__item"> <a href="/news/new-viral-surveillance-system-west-africa-showing-world-how-prevent-next-pandemic"><picture> <source srcset="/files/styles/multiple_ct_sidebar_link_with_image_desktop_xl/public/longstory/7F5A5285%20%281%29.JPG?itok=_7gBfUIk 1x" media="all and (min-width: 1921px)" type="image/jpeg" width="104" height="104"> <source srcset="/files/styles/multiple_ct_sidebar_link_with_image_desktop_xl/public/longstory/7F5A5285%20%281%29.JPG?itok=_7gBfUIk 1x" media="all and (min-width: 1601px) and (max-width: 1920px)" type="image/jpeg" width="104" height="104"> <source srcset="/files/styles/multiple_ct_sidebar_link_with_image_desktop/public/longstory/7F5A5285%20%281%29.JPG?itok=7gPRQMVG 1x" media="all and (min-width: 1340px) and (max-width: 1600px)" type="image/jpeg" width="87" height="104"> <source srcset="/files/styles/multiple_ct_sidebar_link_with_image_desktop/public/longstory/7F5A5285%20%281%29.JPG?itok=7gPRQMVG 1x" media="all and (min-width: 800px) and (max-width: 1339px)" type="image/jpeg" width="87" height="104"> <source srcset="/files/styles/multiple_ct_sidebar_link_with_image_tablet/public/longstory/7F5A5285%20%281%29.JPG?itok=vS0v4syD 1x" media="all and (min-width: 540px) and (max-width: 799px)" type="image/jpeg" width="285" height="186"> <source srcset="/files/styles/multiple_ct_sidebar_link_with_image_phone/public/longstory/7F5A5285%20%281%29.JPG?itok=uvaL-P0e 1x" media="all and (max-width: 539px)" type="image/jpeg" width="220" height="186"> <img loading="eager" width="220" height="186" src="/files/styles/multiple_ct_sidebar_link_with_image_phone/public/longstory/7F5A5285%20%281%29.JPG?itok=uvaL-P0e" alt="Christian Happi and Pardis Sabeti stand outside Redeemer's University" title="Christian Happi and Pardis Sabeti stand outside Redeemer's University" typeof="foaf:Image"> </picture></a> </div> </article> </div> <div class="node__content"> <a href="/news/new-viral-surveillance-system-west-africa-showing-world-how-prevent-next-pandemic" class="node__title"><span class="field field--name-title field--type-string field--label-hidden">A new viral surveillance system in West Africa is showing the world how to prevent the next pandemic</span> </a> </div> </article> </div> <div class="field__item"><article about="/news/scientific-coalition-developing-surveillance-system-detecting-emerging-pandemics-real-time" class="node"> <div class="field field--name-field-image field--type-entity-reference field--label-hidden field__item"><article class="media media--type-image media--view-mode-multiple-ct-sidebar-link-with-image"> <div class="field field--name-field-media-image field--type-image field--label-hidden field__item"> <a href="/news/scientific-coalition-developing-surveillance-system-detecting-emerging-pandemics-real-time"><picture> <source srcset="/files/styles/multiple_ct_sidebar_link_with_image_desktop_xl/public/news/images/2020/Sentinel-main-1%20%281%29_0.jpg?h=d3e04ee7&amp;itok=cH_Pghq8 1x" media="all and (min-width: 1921px)" type="image/jpeg" width="104" height="104"> <source srcset="/files/styles/multiple_ct_sidebar_link_with_image_desktop_xl/public/news/images/2020/Sentinel-main-1%20%281%29_0.jpg?h=d3e04ee7&amp;itok=cH_Pghq8 1x" media="all and (min-width: 1601px) and (max-width: 1920px)" type="image/jpeg" width="104" height="104"> <source srcset="/files/styles/multiple_ct_sidebar_link_with_image_desktop/public/news/images/2020/Sentinel-main-1%20%281%29_0.jpg?h=d3e04ee7&amp;itok=cbSnF6TK 1x" media="all and (min-width: 1340px) and (max-width: 1600px)" type="image/jpeg" width="87" height="104"> <source srcset="/files/styles/multiple_ct_sidebar_link_with_image_desktop/public/news/images/2020/Sentinel-main-1%20%281%29_0.jpg?h=d3e04ee7&amp;itok=cbSnF6TK 1x" media="all and (min-width: 800px) and (max-width: 1339px)" type="image/jpeg" width="87" height="104"> <source srcset="/files/styles/multiple_ct_sidebar_link_with_image_tablet/public/news/images/2020/Sentinel-main-1%20%281%29_0.jpg?h=d3e04ee7&amp;itok=1y7ORLrC 1x" media="all and (min-width: 540px) and (max-width: 799px)" type="image/jpeg" width="285" height="186"> <source srcset="/files/styles/multiple_ct_sidebar_link_with_image_phone/public/news/images/2020/Sentinel-main-1%20%281%29_0.jpg?h=d3e04ee7&amp;itok=g6wJU_LZ 1x" media="all and (max-width: 539px)" type="image/jpeg" width="220" height="186"> <img loading="eager" width="220" height="186" src="/files/styles/multiple_ct_sidebar_link_with_image_phone/public/news/images/2020/Sentinel-main-1%20%281%29_0.jpg?h=d3e04ee7&amp;itok=g6wJU_LZ" alt typeof="foaf:Image"> </picture></a> </div> </article> </div> <div class="node__content"> <a href="/news/scientific-coalition-developing-surveillance-system-detecting-emerging-pandemics-real-time" class="node__title"><span class="field field--name-title field--type-string field--label-hidden">Scientific coalition developing surveillance system for detecting emerging pandemics in real-time</span> </a> </div> </article> </div> </div> </div> </div> </div> </div> <div class="clearfix text-formatted field field--name-field-text field--type-text-long field--label-hidden field__item"><p>The MacArthur Foundation and its nonprofit affiliate, Lever for Change, have announced the <a href="https://www.sentinelpandemicprevention.org/">Sentinel program</a> as one of five finalists in the 100&amp;Change competition.</p> <p>100&amp;Change is a global competition awarding a single $100 million grant to help solve one of the world's most critical social challenges. The competition has influenced the philanthropic sector by encouraging funders to adopt large-scale, collaborative approaches to problem-solving.</p> <p>The Sentinel program, led by <a href="/bios/pardis-sabeti">Pardis Sabeti</a> at the ӳý and <a href="https://staff.run.edu.ng/process.php?qp=RUN%2FREG%2FSS%2FPF%2F536&amp;active=vprofile">Christian Happi</a> at the Institute for Genomics and Global Health (IGH) at Redeemer’s University, Nigeria, is a pandemic prevention system that deploys cutting-edge genomic and data technologies to empower communities to stop epidemics through pathogen surveillance and outbreak response. Launched in 2020 thanks to support from Flu Lab and a cohort of generous donors through TED’s Audacious Project, including the ELMA Foundation, MacKenzie Scott, the Skoll Foundation, and Open Philanthropy, it was piloted in West Africa where it has already had a huge impact, helping frontline workers respond to COVID-19, mpox, Marburg, Ebola, and Lassa fever.</p> <p>“We say ‘detect, connect, and empower,’” explained Sabeti. “Detect any pathogen anywhere around the world, connect that information so it can be shared and acted upon, and empower every actor in the system — every frontline worker, every citizen&nbsp; — to work collectively towards stopping outbreaks from spreading.”</p> <p>Sentinel aims to transform outbreak detection and response in Africa and around the world by training thousands of health workers, achieving national-scale disease surveillance programs, and enabling rapid outbreak detection and response scale-up, thereby profoundly impacting millions of lives and strengthening global health security.</p> <p>“We are at a critical inflection point in our ability to prepare for and respond to future deadly epidemic and pandemic threats,” said Happi. “The Sentinel program will help build a resilient infectious disease surveillance response network, codify and scale our training programs for local scientists and public health workers, and ensure sustainable outbreak response capacity throughout Africa and across the world.”<br> &nbsp;</p> <p><iframe allow="accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share" allowfullscreen frameborder="0" height="315" src="https://www.youtube.com/embed/OSekY1gppLE?si=SwDrJa-6DAD-ehot" title="YouTube video player" width="560"></iframe></p> <p>&nbsp;<br> “Now is the time to dream big, collaborate deeply, and develop new solutions to change the world,” said MacArthur President John Palfrey. “Our 100&amp;Change finalists want to scale ambitious ideas that will help millions of people. Today, we hope the sector finds inspiration in these important projects and joins us in celebrating this milestone in the competition.”</p> <p>100&amp;Change received more than 800 applications from organizations and collaborations worldwide, with each proposal identifying a problem and presenting a compelling solution that is impactful, evidence-based, feasible, durable, and just. The <a href="https://www.100andchange.org/results/finalists">selected finalists</a> represent transformative projects that have the potential to drive meaningful change on a global scale.</p> <p>The final award recipient will be selected by MacArthur’s Board of Directors and announced later this year.</p> </div> </div> </div> </div> </div> </div> </div> <div class="content-section container"> <div class="content-section__main"> <div class="block-node-broad-tags block block-layout-builder block-field-blocknodelong-storyfield-broad-tags"> <div class="block-node-broad-tags__row"> <div class="block-node-broad-tags__title">Tags:</div> <div class="field field--name-field-broad-tags field--type-entity-reference field--label-hidden field__items"> <div class="field__item"><a href="/broad-tags/infectious-disease-and-microbiome-0" hreflang="en">Infectious Disease and Microbiome Program</a></div> <div class="field__item"><a href="/broad-tags/infectious-disease" hreflang="en">Infectious Disease</a></div> <div class="field__item"><a href="/broad-tags/pardis-sabeti" hreflang="en">Pardis Sabeti</a></div> </div> </div> </div> </div> </div> Fri, 08 Mar 2024 15:00:00 +0000 chenders@broadinstitute.org 5556586 at With AI, researchers identify a new class of antibiotic candidates /news/researchers-use-ai-identify-new-class-antibiotic-candidates <span class="field field--name-title field--type-string field--label-hidden"><h1>Sentinel program among finalists for the $100 Million 100&amp;Change competition</h1> </span> <span class="field field--name-uid field--type-entity-reference field--label-hidden"> <span>By Karen Zusi-Tran</span> </span> <span class="field field--name-created field--type-created field--label-hidden"><time datetime="2025-04-29T16:22:58-04:00" class="datetime">April 29, 2025</time> </span> <div class="hero-section container"> <div class="hero-section__row row"> <div class="hero-section__content hero-section__content_left col-6"> <div class="hero-section__breadcrumbs"> <div class="block block-system block-system-breadcrumb-block"> <nav class="breadcrumb" role="navigation" aria-labelledby="system-breadcrumb"> <h2 id="system-breadcrumb" class="visually-hidden">Breadcrumb</h2> <ol> <li> <a href="/">Home</a> </li> <li> <a href="/news">News</a> </li> </ol> </nav> </div> </div> <div class="hero-section__title"> <div class="block block-layout-builder block-field-blocknodelong-storytitle"> <span class="field field--name-title field--type-string field--label-hidden"><h1>Sentinel program among finalists for the $100 Million 100&amp;Change competition</h1> </span> </div> </div> <div class="hero-section__description"> <div class="block block-layout-builder block-field-blocknodelong-storybody"> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p>100&amp;Change is a global competition awarding a single $100 million grant to help solve one of the world's most critical social challenges.</p> </div> </div> </div> <div class="hero-section__author"> <div class="block block-layout-builder block-extra-field-blocknodelong-storyextra-field-author-custom"> By ӳý Communications </div> </div> <div class="hero-section__date"> <div class="block block-layout-builder block-field-blocknodelong-storycreated"> <span class="field field--name-created field--type-created field--label-hidden"><time datetime="2025-04-29T16:22:58-04:00" title="Tuesday, April 29, 2025 - 16:22" class="datetime">April 29, 2025</time> </span> </div> </div> </div> <div class="hero-section__right col-6"> <div class="hero-section__image"> <div class="block block-layout-builder block-field-blocknodelong-storyfield-image"> <div class="field field--name-field-image field--type-entity-reference field--label-hidden field__item"> <article class="media media--type-image media--view-mode-multiple-content-types-header"> <div class="field field--name-field-media-image field--type-image field--label-hidden field__item"> <picture> <source srcset="/files/styles/multiple_ct_header_desktop_xl/public/longstory/100Change-Finalists-vid-1920x1080-41-.png?itok=Vp_QxcgW 1x" media="all and (min-width: 1921px)" type="image/png" width="754" height="503"> <source srcset="/files/styles/multiple_ct_header_desktop_xl/public/longstory/100Change-Finalists-vid-1920x1080-41-.png?itok=Vp_QxcgW 1x" media="all and (min-width: 1601px) and (max-width: 1920px)" type="image/png" width="754" height="503"> <source srcset="/files/styles/multiple_ct_header_desktop/public/longstory/100Change-Finalists-vid-1920x1080-41-.png?itok=Zjsyo6YF 1x" media="all and (min-width: 1340px) and (max-width: 1600px)" type="image/png" width="736" height="520"> <source srcset="/files/styles/multiple_ct_header_laptop/public/longstory/100Change-Finalists-vid-1920x1080-41-.png?itok=MLGnAHQL 1x" media="all and (min-width: 800px) and (max-width: 1339px)" type="image/png" width="641" height="451"> <source srcset="/files/styles/multiple_ct_header_tablet/public/longstory/100Change-Finalists-vid-1920x1080-41-.png?itok=iJ44u04g 1x" media="all and (min-width: 540px) and (max-width: 799px)" type="image/png" width="706" height="417"> <source srcset="/files/styles/multiple_ct_header_phone/public/longstory/100Change-Finalists-vid-1920x1080-41-.png?itok=ZApvucFb 1x" media="all and (max-width: 539px)" type="image/png" width="499" height="294"> <img loading="eager" width="499" height="294" src="/files/styles/multiple_ct_header_phone/public/longstory/100Change-Finalists-vid-1920x1080-41-.png?itok=ZApvucFb" alt="Sentinel program among finalists for the $100 Million 100&amp;Change competition." title="Sentinel program among finalists for the $100 Million 100&amp;Change competition." typeof="foaf:Image"> </picture> </div> <div class="media-caption"> <div class="media-caption__description"> Sentinel program among finalists for the $100 Million 100&amp;Change competition. </div> </div> </article> </div> </div> </div> </div> </div> </div> <div class="content-section container"> <div class="content-section__main"> <div class="block block-better-social-sharing-buttons block-social-sharing-buttons-block"> <div style="display: none"><link rel="preload" href="/modules/contrib/better_social_sharing_buttons/assets/dist/sprites/social-icons--no-color.svg" as="image" type="image/svg+xml" crossorigin="anonymous"></div> <div class="social-sharing-buttons"> <a href="https://www.facebook.com/sharer/sharer.php?u=/taxonomy/term/2301/feed&amp;title=" target="_blank" title="Share to Facebook" aria-label="Share to Facebook" class="social-sharing-buttons-button share-facebook" rel="noopener"> <svg aria-hidden="true" width="32px" height="32px" style="border-radius:100%;"> <use href="/modules/contrib/better_social_sharing_buttons/assets/dist/sprites/social-icons--no-color.svg#facebook" /> </svg> </a> <a href="https://twitter.com/intent/tweet?text=+/taxonomy/term/2301/feed" target="_blank" title="Share to 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paragraph--type--text-with-sidebar text-with-sidebar"> <div class="field field--name-field-sidebar field--type-entity-reference-revisions field--label-hidden field__items"> <div class="field__item"> <div class="paragraph paragraph--type--sidebar-articles sidebar-articles"> <div class="sidebar-articles__col"> <div class="clearfix text-formatted field field--name-field-heading field--type-text field--label-hidden field__item"><p>Related News</p> </div> <div class="field field--name-field-content-reference field--type-entity-reference field--label-hidden field__items"> <div class="field__item"><article about="/news/new-viral-surveillance-system-west-africa-showing-world-how-prevent-next-pandemic" class="node"> <div class="field field--name-field-image field--type-entity-reference field--label-hidden field__item"><article class="media media--type-image media--view-mode-multiple-ct-sidebar-link-with-image"> <div class="field field--name-field-media-image field--type-image 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href="/news/new-viral-surveillance-system-west-africa-showing-world-how-prevent-next-pandemic" class="node__title"><span class="field field--name-title field--type-string field--label-hidden">A new viral surveillance system in West Africa is showing the world how to prevent the next pandemic</span> </a> </div> </article> </div> <div class="field__item"><article about="/news/scientific-coalition-developing-surveillance-system-detecting-emerging-pandemics-real-time" class="node"> <div class="field field--name-field-image field--type-entity-reference field--label-hidden field__item"><article class="media media--type-image media--view-mode-multiple-ct-sidebar-link-with-image"> <div class="field field--name-field-media-image field--type-image field--label-hidden field__item"> <a href="/news/scientific-coalition-developing-surveillance-system-detecting-emerging-pandemics-real-time"><picture> <source 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type="image/jpeg" width="87" height="104"> <source srcset="/files/styles/multiple_ct_sidebar_link_with_image_tablet/public/news/images/2020/Sentinel-main-1%20%281%29_0.jpg?h=d3e04ee7&amp;itok=1y7ORLrC 1x" media="all and (min-width: 540px) and (max-width: 799px)" type="image/jpeg" width="285" height="186"> <source srcset="/files/styles/multiple_ct_sidebar_link_with_image_phone/public/news/images/2020/Sentinel-main-1%20%281%29_0.jpg?h=d3e04ee7&amp;itok=g6wJU_LZ 1x" media="all and (max-width: 539px)" type="image/jpeg" width="220" height="186"> <img loading="eager" width="220" height="186" src="/files/styles/multiple_ct_sidebar_link_with_image_phone/public/news/images/2020/Sentinel-main-1%20%281%29_0.jpg?h=d3e04ee7&amp;itok=g6wJU_LZ" alt typeof="foaf:Image"> </picture></a> </div> </article> </div> <div class="node__content"> <a href="/news/scientific-coalition-developing-surveillance-system-detecting-emerging-pandemics-real-time" class="node__title"><span class="field field--name-title field--type-string field--label-hidden">Scientific coalition developing surveillance system for detecting emerging pandemics in real-time</span> </a> </div> </article> </div> </div> </div> </div> </div> </div> <div class="clearfix text-formatted field field--name-field-text field--type-text-long field--label-hidden field__item"><p>The MacArthur Foundation and its nonprofit affiliate, Lever for Change, have announced the <a href="https://www.sentinelpandemicprevention.org/">Sentinel program</a> as one of five finalists in the 100&amp;Change competition.</p> <p>100&amp;Change is a global competition awarding a single $100 million grant to help solve one of the world's most critical social challenges. The competition has influenced the philanthropic sector by encouraging funders to adopt large-scale, collaborative approaches to problem-solving.</p> <p>The Sentinel program, led by <a href="/bios/pardis-sabeti">Pardis Sabeti</a> at the ӳý and <a href="https://staff.run.edu.ng/process.php?qp=RUN%2FREG%2FSS%2FPF%2F536&amp;active=vprofile">Christian Happi</a> at the Institute for Genomics and Global Health (IGH) at Redeemer’s University, Nigeria, is a pandemic prevention system that deploys cutting-edge genomic and data technologies to empower communities to stop epidemics through pathogen surveillance and outbreak response. Launched in 2020 thanks to support from Flu Lab and a cohort of generous donors through TED’s Audacious Project, including the ELMA Foundation, MacKenzie Scott, the Skoll Foundation, and Open Philanthropy, it was piloted in West Africa where it has already had a huge impact, helping frontline workers respond to COVID-19, mpox, Marburg, Ebola, and Lassa fever.</p> <p>“We say ‘detect, connect, and empower,’” explained Sabeti. “Detect any pathogen anywhere around the world, connect that information so it can be shared and acted upon, and empower every actor in the system — every frontline worker, every citizen&nbsp; — to work collectively towards stopping outbreaks from spreading.”</p> <p>Sentinel aims to transform outbreak detection and response in Africa and around the world by training thousands of health workers, achieving national-scale disease surveillance programs, and enabling rapid outbreak detection and response scale-up, thereby profoundly impacting millions of lives and strengthening global health security.</p> <p>“We are at a critical inflection point in our ability to prepare for and respond to future deadly epidemic and pandemic threats,” said Happi. “The Sentinel program will help build a resilient infectious disease surveillance response network, codify and scale our training programs for local scientists and public health workers, and ensure sustainable outbreak response capacity throughout Africa and across the world.”<br> &nbsp;</p> <p><iframe allow="accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share" allowfullscreen frameborder="0" height="315" src="https://www.youtube.com/embed/OSekY1gppLE?si=SwDrJa-6DAD-ehot" title="YouTube video player" width="560"></iframe></p> <p>&nbsp;<br> “Now is the time to dream big, collaborate deeply, and develop new solutions to change the world,” said MacArthur President John Palfrey. “Our 100&amp;Change finalists want to scale ambitious ideas that will help millions of people. Today, we hope the sector finds inspiration in these important projects and joins us in celebrating this milestone in the competition.”</p> <p>100&amp;Change received more than 800 applications from organizations and collaborations worldwide, with each proposal identifying a problem and presenting a compelling solution that is impactful, evidence-based, feasible, durable, and just. The <a href="https://www.100andchange.org/results/finalists">selected finalists</a> represent transformative projects that have the potential to drive meaningful change on a global scale.</p> <p>The final award recipient will be selected by MacArthur’s Board of Directors and announced later this year.</p> </div> </div> </div> </div> </div> </div> </div> <div class="content-section container"> <div class="content-section__main"> <div class="block-node-broad-tags block block-layout-builder block-field-blocknodelong-storyfield-broad-tags"> <div class="block-node-broad-tags__row"> <div class="block-node-broad-tags__title">Tags:</div> <div class="field field--name-field-broad-tags field--type-entity-reference field--label-hidden field__items"> <div class="field__item"><a href="/broad-tags/infectious-disease-and-microbiome-0" hreflang="en">Infectious Disease and Microbiome Program</a></div> <div class="field__item"><a href="/broad-tags/infectious-disease" hreflang="en">Infectious Disease</a></div> <div class="field__item"><a href="/broad-tags/pardis-sabeti" hreflang="en">Pardis Sabeti</a></div> </div> </div> </div> </div> </div> Wed, 20 Dec 2023 16:30:46 +0000 tulrich@broadinstitute.org 5556221 at