/ en Tue, 14 Jan 25 05:00:00 -0500 /news/gene-editing-extends-lifespan-mouse-model-prion-disease <span class="field field--name-title field--type-string field--label-hidden">CTD^2 Dashboard</span> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p> The CTD<sup>2</sup> Dashboard is a web resource that links findings from Cancer Target Discovery and Development (CTD<sup>2</sup>) Network Centers, which collectively mine and functionally validate data from large-scale cancer genome characterization initiatives and advance them toward use in precision oncology. The Network developed the open-access CTD<sup>2</sup> Dashboard as a web interface that compiles Network-generated summaries about key cancer biology findings and cancer-relevant results related to genes, proteins, and compounds. Dashboard submissions are ranked with a system of validation tiers to indicate strength of evidence.</p> <p> <strong>Publications</strong></p> <p> <a href="https://www.ncbi.nlm.nih.gov/pubmed/29220450" target="_blank">https://www.ncbi.nlm.nih.gov/pubmed/29220450</a></p> <p> <span style="display:none;">cell line profiling</span></p> </div> <span class="field field--name-uid field--type-entity-reference field--label-hidden"> <span>By Maria Nemchuk</span> </span> <span class="field field--name-created field--type-created field--label-hidden"><time datetime="2017-05-04T11:44:53-04:00" title="Thursday, May 4, 2017 - 11:44" class="datetime">May 4, 2017</time> </span> <div class="field field--name-field-software-link field--type-link field--label-above"> <div class="field__label">Link</div> <div class="field__items"> <div class="field__item"><a href="https://ctd2-dashboard.nci.nih.gov/dashboard/">CTD^2 Dashboard</a></div> </div> </div> <div class="field field--name-field-taxonomy-topic field--type-entity-reference field--label-above"> <div class="field__label">Topic</div> <div class="field__items"> <div class="field__item">Portals</div> <div class="field__item">Cancer</div> <div class="field__item">cell line profiling</div> <div class="field__item">small molecules</div> <div class="field__item">Therapeutic Response</div> </div> </div> <div class="field field--name-field-broad-tags field--type-entity-reference field--label-above"> <div class="field__label">Ó³»­´«Ã½ tags</div> <div class="field__items"> <div class="field__item"><a href="/broad-tags/chemical-biology-and-therapeutics-science" hreflang="en">Chemical Biology and Therapeutics Science Program</a></div> <div class="field__item"><a href="/broad-tags/cancer" hreflang="en">Cancer</a></div> <div class="field__item"><a href="/broad-tags/paul-clemons" hreflang="en">Paul Clemons</a></div> <div class="field__item"><a href="/broad-tags/stuart-schreiber" hreflang="en">Stuart Schreiber</a></div> </div> </div> Tue, 14 Jan 2025 10:00:00 +0000 adicorat 5558086 at /news/therapy-candidate-fatal-prion-diseases-turns-disease-causing-gene <span class="field field--name-title field--type-string field--label-hidden">CTD^2 Dashboard</span> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p> The CTD<sup>2</sup> Dashboard is a web resource that links findings from Cancer Target Discovery and Development (CTD<sup>2</sup>) Network Centers, which collectively mine and functionally validate data from large-scale cancer genome characterization initiatives and advance them toward use in precision oncology. The Network developed the open-access CTD<sup>2</sup> Dashboard as a web interface that compiles Network-generated summaries about key cancer biology findings and cancer-relevant results related to genes, proteins, and compounds. Dashboard submissions are ranked with a system of validation tiers to indicate strength of evidence.</p> <p> <strong>Publications</strong></p> <p> <a href="https://www.ncbi.nlm.nih.gov/pubmed/29220450" target="_blank">https://www.ncbi.nlm.nih.gov/pubmed/29220450</a></p> <p> <span style="display:none;">cell line profiling</span></p> </div> <span class="field field--name-uid field--type-entity-reference field--label-hidden"> <span>By Maria Nemchuk</span> </span> <span class="field field--name-created field--type-created field--label-hidden"><time datetime="2017-05-04T11:44:53-04:00" title="Thursday, May 4, 2017 - 11:44" class="datetime">May 4, 2017</time> </span> <div class="field field--name-field-software-link field--type-link field--label-above"> <div class="field__label">Link</div> <div class="field__items"> <div class="field__item"><a href="https://ctd2-dashboard.nci.nih.gov/dashboard/">CTD^2 Dashboard</a></div> </div> </div> <div class="field field--name-field-taxonomy-topic field--type-entity-reference field--label-above"> <div class="field__label">Topic</div> <div class="field__items"> <div class="field__item">Portals</div> <div class="field__item">Cancer</div> <div class="field__item">cell line profiling</div> <div class="field__item">small molecules</div> <div class="field__item">Therapeutic Response</div> </div> </div> <div class="field field--name-field-broad-tags field--type-entity-reference field--label-above"> <div class="field__label">Ó³»­´«Ã½ tags</div> <div class="field__items"> <div class="field__item"><a href="/broad-tags/chemical-biology-and-therapeutics-science" hreflang="en">Chemical Biology and Therapeutics Science Program</a></div> <div class="field__item"><a href="/broad-tags/cancer" hreflang="en">Cancer</a></div> <div class="field__item"><a href="/broad-tags/paul-clemons" hreflang="en">Paul Clemons</a></div> <div class="field__item"><a href="/broad-tags/stuart-schreiber" hreflang="en">Stuart Schreiber</a></div> </div> </div> Thu, 27 Jun 2024 18:11:10 +0000 Corie Lok 5557021 at /news/improved-prime-editing-system-makes-gene-sized-edits-human-cells-therapeutic-levels <span class="field field--name-title field--type-string field--label-hidden">CTD^2 Dashboard</span> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p> The CTD<sup>2</sup> Dashboard is a web resource that links findings from Cancer Target Discovery and Development (CTD<sup>2</sup>) Network Centers, which collectively mine and functionally validate data from large-scale cancer genome characterization initiatives and advance them toward use in precision oncology. The Network developed the open-access CTD<sup>2</sup> Dashboard as a web interface that compiles Network-generated summaries about key cancer biology findings and cancer-relevant results related to genes, proteins, and compounds. Dashboard submissions are ranked with a system of validation tiers to indicate strength of evidence.</p> <p> <strong>Publications</strong></p> <p> <a href="https://www.ncbi.nlm.nih.gov/pubmed/29220450" target="_blank">https://www.ncbi.nlm.nih.gov/pubmed/29220450</a></p> <p> <span style="display:none;">cell line profiling</span></p> </div> <span class="field field--name-uid field--type-entity-reference field--label-hidden"> <span>By Maria Nemchuk</span> </span> <span class="field field--name-created field--type-created field--label-hidden"><time datetime="2017-05-04T11:44:53-04:00" title="Thursday, May 4, 2017 - 11:44" class="datetime">May 4, 2017</time> </span> <div class="field field--name-field-software-link field--type-link field--label-above"> <div class="field__label">Link</div> <div class="field__items"> <div class="field__item"><a href="https://ctd2-dashboard.nci.nih.gov/dashboard/">CTD^2 Dashboard</a></div> </div> </div> <div class="field field--name-field-taxonomy-topic field--type-entity-reference field--label-above"> <div class="field__label">Topic</div> <div class="field__items"> <div class="field__item">Portals</div> <div class="field__item">Cancer</div> <div class="field__item">cell line profiling</div> <div class="field__item">small molecules</div> <div class="field__item">Therapeutic Response</div> </div> </div> <div class="field field--name-field-broad-tags field--type-entity-reference field--label-above"> <div class="field__label">Ó³»­´«Ã½ tags</div> <div class="field__items"> <div class="field__item"><a href="/broad-tags/chemical-biology-and-therapeutics-science" hreflang="en">Chemical Biology and Therapeutics Science Program</a></div> <div class="field__item"><a href="/broad-tags/cancer" hreflang="en">Cancer</a></div> <div class="field__item"><a href="/broad-tags/paul-clemons" hreflang="en">Paul Clemons</a></div> <div class="field__item"><a href="/broad-tags/stuart-schreiber" hreflang="en">Stuart Schreiber</a></div> </div> </div> Mon, 10 Jun 2024 09:30:00 +0000 adicorat 5556946 at