Regev Lab / en Thu, 28 Apr 22 14:01:31 -0400 Researchers use CRISPR to build melanoma models from scratch using human cells /news/researchers-use-crispr-build-melanoma-models-scratch-using-human-cells <span class="field field--name-title field--type-string field--label-hidden">Ó³»­´«Ã½-Novartis Cancer Cell Line Encyclopedia (CCLE)</span> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p> The Cancer Cell Line Encyclopedia (CCLE) project is an effort to conduct a detailed genetic characterization of a large panel of human cancer cell lines. The CCLE provides public access analysis and visualization of DNA copy number, mRNA expression, mutation data and more, for 1000 cancer cell lines. The Cancer Cell Line Encyclopedia (CCLE) project is an effort to conduct a detailed genetic characterization of a large panel of human cancer cell lines. The CCLE provides public access analysis and visualization of DNA copy number, mRNA expression, mutation data and more, for 1000 cancer cell lines.</p> <p> <span style="display:none;">cell line profiling</span></p> </div> <span class="field field--name-uid field--type-entity-reference field--label-hidden"> <span>By bistline@broadinstitute.org</span> </span> <span class="field field--name-created field--type-created field--label-hidden"><time datetime="2012-02-16T15:36:59-05:00" title="Thursday, February 16, 2012 - 15:36" class="datetime">February 16, 2012</time> </span> <div class="field field--name-field-software-link field--type-link field--label-above"> <div class="field__label">Link</div> <div class="field__items"> <div class="field__item"><a href="https://portals.broadinstitute.org/ccle/home">CCLE</a></div> </div> </div> <div class="field field--name-field-taxonomy-topic field--type-entity-reference field--label-above"> <div class="field__label">Topic</div> <div class="field__items"> <div class="field__item">cell lines</div> <div class="field__item">CCLE</div> <div class="field__item">cancer portals</div> <div class="field__item">cancer models</div> <div class="field__item">Cancer</div> <div class="field__item">cancer dependency</div> <div class="field__item">dependency map</div> <div class="field__item">cell line profiling</div> </div> </div> <div class="field field--name-field-broad-tags field--type-entity-reference field--label-above"> <div class="field__label">Ó³»­´«Ã½ tags</div> <div class="field__items"> <div class="field__item"><a href="/broad-tags/cancer-program" hreflang="en">Cancer Program</a></div> <div class="field__item"><a href="/broad-tags/cancer" hreflang="en">Cancer</a></div> </div> </div> Thu, 28 Apr 2022 18:01:31 +0000 adicorat 1130946 at An ‘oracle’ for predicting the evolution of gene regulation /news/%E2%80%98oracle%E2%80%99-predicting-evolution-gene-regulation <span class="field field--name-title field--type-string field--label-hidden">Ó³»­´«Ã½-Novartis Cancer Cell Line Encyclopedia (CCLE)</span> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p> The Cancer Cell Line Encyclopedia (CCLE) project is an effort to conduct a detailed genetic characterization of a large panel of human cancer cell lines. The CCLE provides public access analysis and visualization of DNA copy number, mRNA expression, mutation data and more, for 1000 cancer cell lines. The Cancer Cell Line Encyclopedia (CCLE) project is an effort to conduct a detailed genetic characterization of a large panel of human cancer cell lines. The CCLE provides public access analysis and visualization of DNA copy number, mRNA expression, mutation data and more, for 1000 cancer cell lines.</p> <p> <span style="display:none;">cell line profiling</span></p> </div> <span class="field field--name-uid field--type-entity-reference field--label-hidden"> <span>By bistline@broadinstitute.org</span> </span> <span class="field field--name-created field--type-created field--label-hidden"><time datetime="2012-02-16T15:36:59-05:00" title="Thursday, February 16, 2012 - 15:36" class="datetime">February 16, 2012</time> </span> <div class="field field--name-field-software-link field--type-link field--label-above"> <div class="field__label">Link</div> <div class="field__items"> <div class="field__item"><a href="https://portals.broadinstitute.org/ccle/home">CCLE</a></div> </div> </div> <div class="field field--name-field-taxonomy-topic field--type-entity-reference field--label-above"> <div class="field__label">Topic</div> <div class="field__items"> <div class="field__item">cell lines</div> <div class="field__item">CCLE</div> <div class="field__item">cancer portals</div> <div class="field__item">cancer models</div> <div class="field__item">Cancer</div> <div class="field__item">cancer dependency</div> <div class="field__item">dependency map</div> <div class="field__item">cell line profiling</div> </div> </div> <div class="field field--name-field-broad-tags field--type-entity-reference field--label-above"> <div class="field__label">Ó³»­´«Ã½ tags</div> <div class="field__items"> <div class="field__item"><a href="/broad-tags/cancer-program" hreflang="en">Cancer Program</a></div> <div class="field__item"><a href="/broad-tags/cancer" hreflang="en">Cancer</a></div> </div> </div> Wed, 09 Mar 2022 18:05:33 +0000 tulrich@broadinstitute.org 1127701 at New high-throughput method greatly expands view of how mutations impact cells /news/new-high-throughput-method-greatly-expands-view-how-mutations-impact-cells <span class="field field--name-title field--type-string field--label-hidden">Ó³»­´«Ã½-Novartis Cancer Cell Line Encyclopedia (CCLE)</span> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p> The Cancer Cell Line Encyclopedia (CCLE) project is an effort to conduct a detailed genetic characterization of a large panel of human cancer cell lines. The CCLE provides public access analysis and visualization of DNA copy number, mRNA expression, mutation data and more, for 1000 cancer cell lines. The Cancer Cell Line Encyclopedia (CCLE) project is an effort to conduct a detailed genetic characterization of a large panel of human cancer cell lines. The CCLE provides public access analysis and visualization of DNA copy number, mRNA expression, mutation data and more, for 1000 cancer cell lines.</p> <p> <span style="display:none;">cell line profiling</span></p> </div> <span class="field field--name-uid field--type-entity-reference field--label-hidden"> <span>By bistline@broadinstitute.org</span> </span> <span class="field field--name-created field--type-created field--label-hidden"><time datetime="2012-02-16T15:36:59-05:00" title="Thursday, February 16, 2012 - 15:36" class="datetime">February 16, 2012</time> </span> <div class="field field--name-field-software-link field--type-link field--label-above"> <div class="field__label">Link</div> <div class="field__items"> <div class="field__item"><a href="https://portals.broadinstitute.org/ccle/home">CCLE</a></div> </div> </div> <div class="field field--name-field-taxonomy-topic field--type-entity-reference field--label-above"> <div class="field__label">Topic</div> <div class="field__items"> <div class="field__item">cell lines</div> <div class="field__item">CCLE</div> <div class="field__item">cancer portals</div> <div class="field__item">cancer models</div> <div class="field__item">Cancer</div> <div class="field__item">cancer dependency</div> <div class="field__item">dependency map</div> <div class="field__item">cell line profiling</div> </div> </div> <div class="field field--name-field-broad-tags field--type-entity-reference field--label-above"> <div class="field__label">Ó³»­´«Ã½ tags</div> <div class="field__items"> <div class="field__item"><a href="/broad-tags/cancer-program" hreflang="en">Cancer Program</a></div> <div class="field__item"><a href="/broad-tags/cancer" hreflang="en">Cancer</a></div> </div> </div> Thu, 20 Jan 2022 16:02:55 +0000 tulrich@broadinstitute.org 1127126 at Large collaboration creates cell atlas of COVID-19 pathology /news/large-collaboration-creates-cell-atlas-covid-19-pathology <span class="field field--name-title field--type-string field--label-hidden">Ó³»­´«Ã½-Novartis Cancer Cell Line Encyclopedia (CCLE)</span> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p> The Cancer Cell Line Encyclopedia (CCLE) project is an effort to conduct a detailed genetic characterization of a large panel of human cancer cell lines. The CCLE provides public access analysis and visualization of DNA copy number, mRNA expression, mutation data and more, for 1000 cancer cell lines. The Cancer Cell Line Encyclopedia (CCLE) project is an effort to conduct a detailed genetic characterization of a large panel of human cancer cell lines. The CCLE provides public access analysis and visualization of DNA copy number, mRNA expression, mutation data and more, for 1000 cancer cell lines.</p> <p> <span style="display:none;">cell line profiling</span></p> </div> <span class="field field--name-uid field--type-entity-reference field--label-hidden"> <span>By bistline@broadinstitute.org</span> </span> <span class="field field--name-created field--type-created field--label-hidden"><time datetime="2012-02-16T15:36:59-05:00" title="Thursday, February 16, 2012 - 15:36" class="datetime">February 16, 2012</time> </span> <div class="field field--name-field-software-link field--type-link field--label-above"> <div class="field__label">Link</div> <div class="field__items"> <div class="field__item"><a href="https://portals.broadinstitute.org/ccle/home">CCLE</a></div> </div> </div> <div class="field field--name-field-taxonomy-topic field--type-entity-reference field--label-above"> <div class="field__label">Topic</div> <div class="field__items"> <div class="field__item">cell lines</div> <div class="field__item">CCLE</div> <div class="field__item">cancer portals</div> <div class="field__item">cancer models</div> <div class="field__item">Cancer</div> <div class="field__item">cancer dependency</div> <div class="field__item">dependency map</div> <div class="field__item">cell line profiling</div> </div> </div> <div class="field field--name-field-broad-tags field--type-entity-reference field--label-above"> <div class="field__label">Ó³»­´«Ã½ tags</div> <div class="field__items"> <div class="field__item"><a href="/broad-tags/cancer-program" hreflang="en">Cancer Program</a></div> <div class="field__item"><a href="/broad-tags/cancer" hreflang="en">Cancer</a></div> </div> </div> Thu, 29 Apr 2021 12:50:48 +0000 Corie Lok 856156 at #WhyIScience Q&A: A computational and molecular biologist helps inspire the next generation of scientists /blog/whyiscience-qa-computational-and-molecular-biologist-helps-inspire-next-generation-scientists <span class="field field--name-title field--type-string field--label-hidden">Ó³»­´«Ã½-Novartis Cancer Cell Line Encyclopedia (CCLE)</span> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p> The Cancer Cell Line Encyclopedia (CCLE) project is an effort to conduct a detailed genetic characterization of a large panel of human cancer cell lines. The CCLE provides public access analysis and visualization of DNA copy number, mRNA expression, mutation data and more, for 1000 cancer cell lines. The Cancer Cell Line Encyclopedia (CCLE) project is an effort to conduct a detailed genetic characterization of a large panel of human cancer cell lines. The CCLE provides public access analysis and visualization of DNA copy number, mRNA expression, mutation data and more, for 1000 cancer cell lines.</p> <p> <span style="display:none;">cell line profiling</span></p> </div> <span class="field field--name-uid field--type-entity-reference field--label-hidden"> <span>By bistline@broadinstitute.org</span> </span> <span class="field field--name-created field--type-created field--label-hidden"><time datetime="2012-02-16T15:36:59-05:00" title="Thursday, February 16, 2012 - 15:36" class="datetime">February 16, 2012</time> </span> <div class="field field--name-field-software-link field--type-link field--label-above"> <div class="field__label">Link</div> <div class="field__items"> <div class="field__item"><a href="https://portals.broadinstitute.org/ccle/home">CCLE</a></div> </div> </div> <div class="field field--name-field-taxonomy-topic field--type-entity-reference field--label-above"> <div class="field__label">Topic</div> <div class="field__items"> <div class="field__item">cell lines</div> <div class="field__item">CCLE</div> <div class="field__item">cancer portals</div> <div class="field__item">cancer models</div> <div class="field__item">Cancer</div> <div class="field__item">cancer dependency</div> <div class="field__item">dependency map</div> <div class="field__item">cell line profiling</div> </div> </div> <div class="field field--name-field-broad-tags field--type-entity-reference field--label-above"> <div class="field__label">Ó³»­´«Ã½ tags</div> <div class="field__items"> <div class="field__item"><a href="/broad-tags/cancer-program" hreflang="en">Cancer Program</a></div> <div class="field__item"><a href="/broad-tags/cancer" hreflang="en">Cancer</a></div> </div> </div> Mon, 29 Mar 2021 13:15:31 +0000 Eilidh Gilbert 816861 at New single-cell technology points to mechanism of cancer immunotherapy resistance /news/new-single-cell-technology-points-mechanism-cancer-immunotherapy-resistance <span class="field field--name-title field--type-string field--label-hidden">Ó³»­´«Ã½-Novartis Cancer Cell Line Encyclopedia (CCLE)</span> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p> The Cancer Cell Line Encyclopedia (CCLE) project is an effort to conduct a detailed genetic characterization of a large panel of human cancer cell lines. The CCLE provides public access analysis and visualization of DNA copy number, mRNA expression, mutation data and more, for 1000 cancer cell lines. The Cancer Cell Line Encyclopedia (CCLE) project is an effort to conduct a detailed genetic characterization of a large panel of human cancer cell lines. The CCLE provides public access analysis and visualization of DNA copy number, mRNA expression, mutation data and more, for 1000 cancer cell lines.</p> <p> <span style="display:none;">cell line profiling</span></p> </div> <span class="field field--name-uid field--type-entity-reference field--label-hidden"> <span>By bistline@broadinstitute.org</span> </span> <span class="field field--name-created field--type-created field--label-hidden"><time datetime="2012-02-16T15:36:59-05:00" title="Thursday, February 16, 2012 - 15:36" class="datetime">February 16, 2012</time> </span> <div class="field field--name-field-software-link field--type-link field--label-above"> <div class="field__label">Link</div> <div class="field__items"> <div class="field__item"><a href="https://portals.broadinstitute.org/ccle/home">CCLE</a></div> </div> </div> <div class="field field--name-field-taxonomy-topic field--type-entity-reference field--label-above"> <div class="field__label">Topic</div> <div class="field__items"> <div class="field__item">cell lines</div> <div class="field__item">CCLE</div> <div class="field__item">cancer portals</div> <div class="field__item">cancer models</div> <div class="field__item">Cancer</div> <div class="field__item">cancer dependency</div> <div class="field__item">dependency map</div> <div class="field__item">cell line profiling</div> </div> </div> <div class="field field--name-field-broad-tags field--type-entity-reference field--label-above"> <div class="field__label">Ó³»­´«Ã½ tags</div> <div class="field__items"> <div class="field__item"><a href="/broad-tags/cancer-program" hreflang="en">Cancer Program</a></div> <div class="field__item"><a href="/broad-tags/cancer" hreflang="en">Cancer</a></div> </div> </div> Mon, 08 Mar 2021 16:23:52 +0000 Corie Lok 789441 at A single-cell atlas of nerve cells in the gut reveals web of connections /news/single-cell-atlas-nerve-cells-gut-reveals-web-connections <span class="field field--name-title field--type-string field--label-hidden">Ó³»­´«Ã½-Novartis Cancer Cell Line Encyclopedia (CCLE)</span> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p> The Cancer Cell Line Encyclopedia (CCLE) project is an effort to conduct a detailed genetic characterization of a large panel of human cancer cell lines. The CCLE provides public access analysis and visualization of DNA copy number, mRNA expression, mutation data and more, for 1000 cancer cell lines. The Cancer Cell Line Encyclopedia (CCLE) project is an effort to conduct a detailed genetic characterization of a large panel of human cancer cell lines. The CCLE provides public access analysis and visualization of DNA copy number, mRNA expression, mutation data and more, for 1000 cancer cell lines.</p> <p> <span style="display:none;">cell line profiling</span></p> </div> <span class="field field--name-uid field--type-entity-reference field--label-hidden"> <span>By bistline@broadinstitute.org</span> </span> <span class="field field--name-created field--type-created field--label-hidden"><time datetime="2012-02-16T15:36:59-05:00" title="Thursday, February 16, 2012 - 15:36" class="datetime">February 16, 2012</time> </span> <div class="field field--name-field-software-link field--type-link field--label-above"> <div class="field__label">Link</div> <div class="field__items"> <div class="field__item"><a href="https://portals.broadinstitute.org/ccle/home">CCLE</a></div> </div> </div> <div class="field field--name-field-taxonomy-topic field--type-entity-reference field--label-above"> <div class="field__label">Topic</div> <div class="field__items"> <div class="field__item">cell lines</div> <div class="field__item">CCLE</div> <div class="field__item">cancer portals</div> <div class="field__item">cancer models</div> <div class="field__item">Cancer</div> <div class="field__item">cancer dependency</div> <div class="field__item">dependency map</div> <div class="field__item">cell line profiling</div> </div> </div> <div class="field field--name-field-broad-tags field--type-entity-reference field--label-above"> <div class="field__label">Ó³»­´«Ã½ tags</div> <div class="field__items"> <div class="field__item"><a href="/broad-tags/cancer-program" hreflang="en">Cancer Program</a></div> <div class="field__item"><a href="/broad-tags/cancer" hreflang="en">Cancer</a></div> </div> </div> Thu, 03 Sep 2020 15:49:58 +0000 kzusi@broadinstitute.org 647586 at Research Roundup: July 31, 2020 /news/research-roundup-july-31-2020 <span class="field field--name-title field--type-string field--label-hidden">Ó³»­´«Ã½-Novartis Cancer Cell Line Encyclopedia (CCLE)</span> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p> The Cancer Cell Line Encyclopedia (CCLE) project is an effort to conduct a detailed genetic characterization of a large panel of human cancer cell lines. The CCLE provides public access analysis and visualization of DNA copy number, mRNA expression, mutation data and more, for 1000 cancer cell lines. The Cancer Cell Line Encyclopedia (CCLE) project is an effort to conduct a detailed genetic characterization of a large panel of human cancer cell lines. The CCLE provides public access analysis and visualization of DNA copy number, mRNA expression, mutation data and more, for 1000 cancer cell lines.</p> <p> <span style="display:none;">cell line profiling</span></p> </div> <span class="field field--name-uid field--type-entity-reference field--label-hidden"> <span>By bistline@broadinstitute.org</span> </span> <span class="field field--name-created field--type-created field--label-hidden"><time datetime="2012-02-16T15:36:59-05:00" title="Thursday, February 16, 2012 - 15:36" class="datetime">February 16, 2012</time> </span> <div class="field field--name-field-software-link field--type-link field--label-above"> <div class="field__label">Link</div> <div class="field__items"> <div class="field__item"><a href="https://portals.broadinstitute.org/ccle/home">CCLE</a></div> </div> </div> <div class="field field--name-field-taxonomy-topic field--type-entity-reference field--label-above"> <div class="field__label">Topic</div> <div class="field__items"> <div class="field__item">cell lines</div> <div class="field__item">CCLE</div> <div class="field__item">cancer portals</div> <div class="field__item">cancer models</div> <div class="field__item">Cancer</div> <div class="field__item">cancer dependency</div> <div class="field__item">dependency map</div> <div class="field__item">cell line profiling</div> </div> </div> <div class="field field--name-field-broad-tags field--type-entity-reference field--label-above"> <div class="field__label">Ó³»­´«Ã½ tags</div> <div class="field__items"> <div class="field__item"><a href="/broad-tags/cancer-program" hreflang="en">Cancer Program</a></div> <div class="field__item"><a href="/broad-tags/cancer" hreflang="en">Cancer</a></div> </div> </div> Fri, 31 Jul 2020 15:36:28 +0000 Namrata Sengupta 635586 at How the Ó³»­´«Ã½ is helping understand and overcome COVID-19 /news/how-broad-institute-helping-understand-and-overcome-covid-19 <span class="field field--name-title field--type-string field--label-hidden">Ó³»­´«Ã½-Novartis Cancer Cell Line Encyclopedia (CCLE)</span> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p> The Cancer Cell Line Encyclopedia (CCLE) project is an effort to conduct a detailed genetic characterization of a large panel of human cancer cell lines. The CCLE provides public access analysis and visualization of DNA copy number, mRNA expression, mutation data and more, for 1000 cancer cell lines. The Cancer Cell Line Encyclopedia (CCLE) project is an effort to conduct a detailed genetic characterization of a large panel of human cancer cell lines. The CCLE provides public access analysis and visualization of DNA copy number, mRNA expression, mutation data and more, for 1000 cancer cell lines.</p> <p> <span style="display:none;">cell line profiling</span></p> </div> <span class="field field--name-uid field--type-entity-reference field--label-hidden"> <span>By bistline@broadinstitute.org</span> </span> <span class="field field--name-created field--type-created field--label-hidden"><time datetime="2012-02-16T15:36:59-05:00" title="Thursday, February 16, 2012 - 15:36" class="datetime">February 16, 2012</time> </span> <div class="field field--name-field-software-link field--type-link field--label-above"> <div class="field__label">Link</div> <div class="field__items"> <div class="field__item"><a href="https://portals.broadinstitute.org/ccle/home">CCLE</a></div> </div> </div> <div class="field field--name-field-taxonomy-topic field--type-entity-reference field--label-above"> <div class="field__label">Topic</div> <div class="field__items"> <div class="field__item">cell lines</div> <div class="field__item">CCLE</div> <div class="field__item">cancer portals</div> <div class="field__item">cancer models</div> <div class="field__item">Cancer</div> <div class="field__item">cancer dependency</div> <div class="field__item">dependency map</div> <div class="field__item">cell line profiling</div> </div> </div> <div class="field field--name-field-broad-tags field--type-entity-reference field--label-above"> <div class="field__label">Ó³»­´«Ã½ tags</div> <div class="field__items"> <div class="field__item"><a href="/broad-tags/cancer-program" hreflang="en">Cancer Program</a></div> <div class="field__item"><a href="/broad-tags/cancer" hreflang="en">Cancer</a></div> </div> </div> Wed, 22 Apr 2020 15:20:16 +0000 Corie Lok 627646 at Epidemiology & Surveillance /coronavirus/epidemiology-surveillance <span class="field field--name-title field--type-string field--label-hidden">Ó³»­´«Ã½-Novartis Cancer Cell Line Encyclopedia (CCLE)</span> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p> The Cancer Cell Line Encyclopedia (CCLE) project is an effort to conduct a detailed genetic characterization of a large panel of human cancer cell lines. The CCLE provides public access analysis and visualization of DNA copy number, mRNA expression, mutation data and more, for 1000 cancer cell lines. The Cancer Cell Line Encyclopedia (CCLE) project is an effort to conduct a detailed genetic characterization of a large panel of human cancer cell lines. The CCLE provides public access analysis and visualization of DNA copy number, mRNA expression, mutation data and more, for 1000 cancer cell lines.</p> <p> <span style="display:none;">cell line profiling</span></p> </div> <span class="field field--name-uid field--type-entity-reference field--label-hidden"> <span>By bistline@broadinstitute.org</span> </span> <span class="field field--name-created field--type-created field--label-hidden"><time datetime="2012-02-16T15:36:59-05:00" title="Thursday, February 16, 2012 - 15:36" class="datetime">February 16, 2012</time> </span> <div class="field field--name-field-software-link field--type-link field--label-above"> <div class="field__label">Link</div> <div class="field__items"> <div class="field__item"><a href="https://portals.broadinstitute.org/ccle/home">CCLE</a></div> </div> </div> <div class="field field--name-field-taxonomy-topic field--type-entity-reference field--label-above"> <div class="field__label">Topic</div> <div class="field__items"> <div class="field__item">cell lines</div> <div class="field__item">CCLE</div> <div class="field__item">cancer portals</div> <div class="field__item">cancer models</div> <div class="field__item">Cancer</div> <div class="field__item">cancer dependency</div> <div class="field__item">dependency map</div> <div class="field__item">cell line profiling</div> </div> </div> <div class="field field--name-field-broad-tags field--type-entity-reference field--label-above"> <div class="field__label">Ó³»­´«Ã½ tags</div> <div class="field__items"> <div class="field__item"><a href="/broad-tags/cancer-program" hreflang="en">Cancer Program</a></div> <div class="field__item"><a href="/broad-tags/cancer" hreflang="en">Cancer</a></div> </div> </div> Tue, 21 Apr 2020 20:20:36 +0000 admin 628241 at