Aviv Regev / en Thu, 28 Apr 22 14:01:31 -0400 Researchers use CRISPR to build melanoma models from scratch using human cells /news/researchers-use-crispr-build-melanoma-models-scratch-using-human-cells <span class="field field--name-title field--type-string field--label-hidden">ӳý-Novartis Cancer Cell Line Encyclopedia (CCLE)</span> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p> The Cancer Cell Line Encyclopedia (CCLE) project is an effort to conduct a detailed genetic characterization of a large panel of human cancer cell lines. The CCLE provides public access analysis and visualization of DNA copy number, mRNA expression, mutation data and more, for 1000 cancer cell lines. The Cancer Cell Line Encyclopedia (CCLE) project is an effort to conduct a detailed genetic characterization of a large panel of human cancer cell lines. The CCLE provides public access analysis and visualization of DNA copy number, mRNA expression, mutation data and more, for 1000 cancer cell lines.</p> <p> <span style="display:none;">cell line profiling</span></p> </div> <span class="field field--name-uid field--type-entity-reference field--label-hidden"> <span>By bistline@broadinstitute.org</span> </span> <span class="field field--name-created field--type-created field--label-hidden"><time datetime="2012-02-16T15:36:59-05:00" title="Thursday, February 16, 2012 - 15:36" class="datetime">February 16, 2012</time> </span> <div class="field field--name-field-software-link field--type-link field--label-above"> <div class="field__label">Link</div> <div class="field__items"> <div class="field__item"><a href="https://portals.broadinstitute.org/ccle/home">CCLE</a></div> </div> </div> <div class="field field--name-field-taxonomy-topic field--type-entity-reference field--label-above"> <div class="field__label">Topic</div> <div class="field__items"> <div class="field__item">cell lines</div> <div class="field__item">CCLE</div> <div class="field__item">cancer portals</div> <div class="field__item">cancer models</div> <div class="field__item">Cancer</div> <div class="field__item">cancer dependency</div> <div class="field__item">dependency map</div> <div class="field__item">cell line profiling</div> </div> </div> <div class="field field--name-field-broad-tags field--type-entity-reference field--label-above"> <div class="field__label">ӳý tags</div> <div class="field__items"> <div class="field__item"><a href="/broad-tags/cancer-program" hreflang="en">Cancer Program</a></div> <div class="field__item"><a href="/broad-tags/cancer" hreflang="en">Cancer</a></div> </div> </div> Thu, 28 Apr 2022 18:01:31 +0000 adicorat 1130946 at An ‘oracle’ for predicting the evolution of gene regulation /news/%E2%80%98oracle%E2%80%99-predicting-evolution-gene-regulation <span class="field field--name-title field--type-string field--label-hidden">ӳý-Novartis Cancer Cell Line Encyclopedia (CCLE)</span> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p> The Cancer Cell Line Encyclopedia (CCLE) project is an effort to conduct a detailed genetic characterization of a large panel of human cancer cell lines. The CCLE provides public access analysis and visualization of DNA copy number, mRNA expression, mutation data and more, for 1000 cancer cell lines. The Cancer Cell Line Encyclopedia (CCLE) project is an effort to conduct a detailed genetic characterization of a large panel of human cancer cell lines. The CCLE provides public access analysis and visualization of DNA copy number, mRNA expression, mutation data and more, for 1000 cancer cell lines.</p> <p> <span style="display:none;">cell line profiling</span></p> </div> <span class="field field--name-uid field--type-entity-reference field--label-hidden"> <span>By bistline@broadinstitute.org</span> </span> <span class="field field--name-created field--type-created field--label-hidden"><time datetime="2012-02-16T15:36:59-05:00" title="Thursday, February 16, 2012 - 15:36" class="datetime">February 16, 2012</time> </span> <div class="field field--name-field-software-link field--type-link field--label-above"> <div class="field__label">Link</div> <div class="field__items"> <div class="field__item"><a href="https://portals.broadinstitute.org/ccle/home">CCLE</a></div> </div> </div> <div class="field field--name-field-taxonomy-topic field--type-entity-reference field--label-above"> <div class="field__label">Topic</div> <div class="field__items"> <div class="field__item">cell lines</div> <div class="field__item">CCLE</div> <div class="field__item">cancer portals</div> <div class="field__item">cancer models</div> <div class="field__item">Cancer</div> <div class="field__item">cancer dependency</div> <div class="field__item">dependency map</div> <div class="field__item">cell line profiling</div> </div> </div> <div class="field field--name-field-broad-tags field--type-entity-reference field--label-above"> <div class="field__label">ӳý tags</div> <div class="field__items"> <div class="field__item"><a href="/broad-tags/cancer-program" hreflang="en">Cancer Program</a></div> <div class="field__item"><a href="/broad-tags/cancer" hreflang="en">Cancer</a></div> </div> </div> Wed, 09 Mar 2022 18:05:33 +0000 tulrich@broadinstitute.org 1127701 at New high-throughput method greatly expands view of how mutations impact cells /news/new-high-throughput-method-greatly-expands-view-how-mutations-impact-cells <span class="field field--name-title field--type-string field--label-hidden">ӳý-Novartis Cancer Cell Line Encyclopedia (CCLE)</span> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p> The Cancer Cell Line Encyclopedia (CCLE) project is an effort to conduct a detailed genetic characterization of a large panel of human cancer cell lines. The CCLE provides public access analysis and visualization of DNA copy number, mRNA expression, mutation data and more, for 1000 cancer cell lines. The Cancer Cell Line Encyclopedia (CCLE) project is an effort to conduct a detailed genetic characterization of a large panel of human cancer cell lines. The CCLE provides public access analysis and visualization of DNA copy number, mRNA expression, mutation data and more, for 1000 cancer cell lines.</p> <p> <span style="display:none;">cell line profiling</span></p> </div> <span class="field field--name-uid field--type-entity-reference field--label-hidden"> <span>By bistline@broadinstitute.org</span> </span> <span class="field field--name-created field--type-created field--label-hidden"><time datetime="2012-02-16T15:36:59-05:00" title="Thursday, February 16, 2012 - 15:36" class="datetime">February 16, 2012</time> </span> <div class="field field--name-field-software-link field--type-link field--label-above"> <div class="field__label">Link</div> <div class="field__items"> <div class="field__item"><a href="https://portals.broadinstitute.org/ccle/home">CCLE</a></div> </div> </div> <div class="field field--name-field-taxonomy-topic field--type-entity-reference field--label-above"> <div class="field__label">Topic</div> <div class="field__items"> <div class="field__item">cell lines</div> <div class="field__item">CCLE</div> <div class="field__item">cancer portals</div> <div class="field__item">cancer models</div> <div class="field__item">Cancer</div> <div class="field__item">cancer dependency</div> <div class="field__item">dependency map</div> <div class="field__item">cell line profiling</div> </div> </div> <div class="field field--name-field-broad-tags field--type-entity-reference field--label-above"> <div class="field__label">ӳý tags</div> <div class="field__items"> <div class="field__item"><a href="/broad-tags/cancer-program" hreflang="en">Cancer Program</a></div> <div class="field__item"><a href="/broad-tags/cancer" hreflang="en">Cancer</a></div> </div> </div> Thu, 20 Jan 2022 16:02:55 +0000 tulrich@broadinstitute.org 1127126 at Researchers discover immune cell “hubs” hiding in tumors /news/researchers-discover-immune-cell-%E2%80%9Chubs%E2%80%9D-hiding-tumors <span class="field field--name-title field--type-string field--label-hidden">ӳý-Novartis Cancer Cell Line Encyclopedia (CCLE)</span> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p> The Cancer Cell Line Encyclopedia (CCLE) project is an effort to conduct a detailed genetic characterization of a large panel of human cancer cell lines. The CCLE provides public access analysis and visualization of DNA copy number, mRNA expression, mutation data and more, for 1000 cancer cell lines. The Cancer Cell Line Encyclopedia (CCLE) project is an effort to conduct a detailed genetic characterization of a large panel of human cancer cell lines. The CCLE provides public access analysis and visualization of DNA copy number, mRNA expression, mutation data and more, for 1000 cancer cell lines.</p> <p> <span style="display:none;">cell line profiling</span></p> </div> <span class="field field--name-uid field--type-entity-reference field--label-hidden"> <span>By bistline@broadinstitute.org</span> </span> <span class="field field--name-created field--type-created field--label-hidden"><time datetime="2012-02-16T15:36:59-05:00" title="Thursday, February 16, 2012 - 15:36" class="datetime">February 16, 2012</time> </span> <div class="field field--name-field-software-link field--type-link field--label-above"> <div class="field__label">Link</div> <div class="field__items"> <div class="field__item"><a href="https://portals.broadinstitute.org/ccle/home">CCLE</a></div> </div> </div> <div class="field field--name-field-taxonomy-topic field--type-entity-reference field--label-above"> <div class="field__label">Topic</div> <div class="field__items"> <div class="field__item">cell lines</div> <div class="field__item">CCLE</div> <div class="field__item">cancer portals</div> <div class="field__item">cancer models</div> <div class="field__item">Cancer</div> <div class="field__item">cancer dependency</div> <div class="field__item">dependency map</div> <div class="field__item">cell line profiling</div> </div> </div> <div class="field field--name-field-broad-tags field--type-entity-reference field--label-above"> <div class="field__label">ӳý tags</div> <div class="field__items"> <div class="field__item"><a href="/broad-tags/cancer-program" hreflang="en">Cancer Program</a></div> <div class="field__item"><a href="/broad-tags/cancer" hreflang="en">Cancer</a></div> </div> </div> Tue, 31 Aug 2021 14:10:29 +0000 Corie Lok 1073766 at A detailed atlas of the developing brain /news/detailed-atlas-developing-brain <span class="field field--name-title field--type-string field--label-hidden">ӳý-Novartis Cancer Cell Line Encyclopedia (CCLE)</span> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p> The Cancer Cell Line Encyclopedia (CCLE) project is an effort to conduct a detailed genetic characterization of a large panel of human cancer cell lines. The CCLE provides public access analysis and visualization of DNA copy number, mRNA expression, mutation data and more, for 1000 cancer cell lines. The Cancer Cell Line Encyclopedia (CCLE) project is an effort to conduct a detailed genetic characterization of a large panel of human cancer cell lines. The CCLE provides public access analysis and visualization of DNA copy number, mRNA expression, mutation data and more, for 1000 cancer cell lines.</p> <p> <span style="display:none;">cell line profiling</span></p> </div> <span class="field field--name-uid field--type-entity-reference field--label-hidden"> <span>By bistline@broadinstitute.org</span> </span> <span class="field field--name-created field--type-created field--label-hidden"><time datetime="2012-02-16T15:36:59-05:00" title="Thursday, February 16, 2012 - 15:36" class="datetime">February 16, 2012</time> </span> <div class="field field--name-field-software-link field--type-link field--label-above"> <div class="field__label">Link</div> <div class="field__items"> <div class="field__item"><a href="https://portals.broadinstitute.org/ccle/home">CCLE</a></div> </div> </div> <div class="field field--name-field-taxonomy-topic field--type-entity-reference field--label-above"> <div class="field__label">Topic</div> <div class="field__items"> <div class="field__item">cell lines</div> <div class="field__item">CCLE</div> <div class="field__item">cancer portals</div> <div class="field__item">cancer models</div> <div class="field__item">Cancer</div> <div class="field__item">cancer dependency</div> <div class="field__item">dependency map</div> <div class="field__item">cell line profiling</div> </div> </div> <div class="field field--name-field-broad-tags field--type-entity-reference field--label-above"> <div class="field__label">ӳý tags</div> <div class="field__items"> <div class="field__item"><a href="/broad-tags/cancer-program" hreflang="en">Cancer Program</a></div> <div class="field__item"><a href="/broad-tags/cancer" hreflang="en">Cancer</a></div> </div> </div> Thu, 24 Jun 2021 13:52:17 +0000 tulrich@broadinstitute.org 954006 at Large collaboration creates cell atlas of COVID-19 pathology /news/large-collaboration-creates-cell-atlas-covid-19-pathology <span class="field field--name-title field--type-string field--label-hidden">ӳý-Novartis Cancer Cell Line Encyclopedia (CCLE)</span> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p> The Cancer Cell Line Encyclopedia (CCLE) project is an effort to conduct a detailed genetic characterization of a large panel of human cancer cell lines. The CCLE provides public access analysis and visualization of DNA copy number, mRNA expression, mutation data and more, for 1000 cancer cell lines. The Cancer Cell Line Encyclopedia (CCLE) project is an effort to conduct a detailed genetic characterization of a large panel of human cancer cell lines. The CCLE provides public access analysis and visualization of DNA copy number, mRNA expression, mutation data and more, for 1000 cancer cell lines.</p> <p> <span style="display:none;">cell line profiling</span></p> </div> <span class="field field--name-uid field--type-entity-reference field--label-hidden"> <span>By bistline@broadinstitute.org</span> </span> <span class="field field--name-created field--type-created field--label-hidden"><time datetime="2012-02-16T15:36:59-05:00" title="Thursday, February 16, 2012 - 15:36" class="datetime">February 16, 2012</time> </span> <div class="field field--name-field-software-link field--type-link field--label-above"> <div class="field__label">Link</div> <div class="field__items"> <div class="field__item"><a href="https://portals.broadinstitute.org/ccle/home">CCLE</a></div> </div> </div> <div class="field field--name-field-taxonomy-topic field--type-entity-reference field--label-above"> <div class="field__label">Topic</div> <div class="field__items"> <div class="field__item">cell lines</div> <div class="field__item">CCLE</div> <div class="field__item">cancer portals</div> <div class="field__item">cancer models</div> <div class="field__item">Cancer</div> <div class="field__item">cancer dependency</div> <div class="field__item">dependency map</div> <div class="field__item">cell line profiling</div> </div> </div> <div class="field field--name-field-broad-tags field--type-entity-reference field--label-above"> <div class="field__label">ӳý tags</div> <div class="field__items"> <div class="field__item"><a href="/broad-tags/cancer-program" hreflang="en">Cancer Program</a></div> <div class="field__item"><a href="/broad-tags/cancer" hreflang="en">Cancer</a></div> </div> </div> Thu, 29 Apr 2021 12:50:48 +0000 Corie Lok 856156 at New single-cell technology points to mechanism of cancer immunotherapy resistance /news/new-single-cell-technology-points-mechanism-cancer-immunotherapy-resistance <span class="field field--name-title field--type-string field--label-hidden">ӳý-Novartis Cancer Cell Line Encyclopedia (CCLE)</span> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p> The Cancer Cell Line Encyclopedia (CCLE) project is an effort to conduct a detailed genetic characterization of a large panel of human cancer cell lines. The CCLE provides public access analysis and visualization of DNA copy number, mRNA expression, mutation data and more, for 1000 cancer cell lines. The Cancer Cell Line Encyclopedia (CCLE) project is an effort to conduct a detailed genetic characterization of a large panel of human cancer cell lines. The CCLE provides public access analysis and visualization of DNA copy number, mRNA expression, mutation data and more, for 1000 cancer cell lines.</p> <p> <span style="display:none;">cell line profiling</span></p> </div> <span class="field field--name-uid field--type-entity-reference field--label-hidden"> <span>By bistline@broadinstitute.org</span> </span> <span class="field field--name-created field--type-created field--label-hidden"><time datetime="2012-02-16T15:36:59-05:00" title="Thursday, February 16, 2012 - 15:36" class="datetime">February 16, 2012</time> </span> <div class="field field--name-field-software-link field--type-link field--label-above"> <div class="field__label">Link</div> <div class="field__items"> <div class="field__item"><a href="https://portals.broadinstitute.org/ccle/home">CCLE</a></div> </div> </div> <div class="field field--name-field-taxonomy-topic field--type-entity-reference field--label-above"> <div class="field__label">Topic</div> <div class="field__items"> <div class="field__item">cell lines</div> <div class="field__item">CCLE</div> <div class="field__item">cancer portals</div> <div class="field__item">cancer models</div> <div class="field__item">Cancer</div> <div class="field__item">cancer dependency</div> <div class="field__item">dependency map</div> <div class="field__item">cell line profiling</div> </div> </div> <div class="field field--name-field-broad-tags field--type-entity-reference field--label-above"> <div class="field__label">ӳý tags</div> <div class="field__items"> <div class="field__item"><a href="/broad-tags/cancer-program" hreflang="en">Cancer Program</a></div> <div class="field__item"><a href="/broad-tags/cancer" hreflang="en">Cancer</a></div> </div> </div> Mon, 08 Mar 2021 16:23:52 +0000 Corie Lok 789441 at New immunotherapy target discovered for malignant brain tumors /news/new-immunotherapy-target-discovered-malignant-brain-tumors <span class="field field--name-title field--type-string field--label-hidden">ӳý-Novartis Cancer Cell Line Encyclopedia (CCLE)</span> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p> The Cancer Cell Line Encyclopedia (CCLE) project is an effort to conduct a detailed genetic characterization of a large panel of human cancer cell lines. The CCLE provides public access analysis and visualization of DNA copy number, mRNA expression, mutation data and more, for 1000 cancer cell lines. The Cancer Cell Line Encyclopedia (CCLE) project is an effort to conduct a detailed genetic characterization of a large panel of human cancer cell lines. The CCLE provides public access analysis and visualization of DNA copy number, mRNA expression, mutation data and more, for 1000 cancer cell lines.</p> <p> <span style="display:none;">cell line profiling</span></p> </div> <span class="field field--name-uid field--type-entity-reference field--label-hidden"> <span>By bistline@broadinstitute.org</span> </span> <span class="field field--name-created field--type-created field--label-hidden"><time datetime="2012-02-16T15:36:59-05:00" title="Thursday, February 16, 2012 - 15:36" class="datetime">February 16, 2012</time> </span> <div class="field field--name-field-software-link field--type-link field--label-above"> <div class="field__label">Link</div> <div class="field__items"> <div class="field__item"><a href="https://portals.broadinstitute.org/ccle/home">CCLE</a></div> </div> </div> <div class="field field--name-field-taxonomy-topic field--type-entity-reference field--label-above"> <div class="field__label">Topic</div> <div class="field__items"> <div class="field__item">cell lines</div> <div class="field__item">CCLE</div> <div class="field__item">cancer portals</div> <div class="field__item">cancer models</div> <div class="field__item">Cancer</div> <div class="field__item">cancer dependency</div> <div class="field__item">dependency map</div> <div class="field__item">cell line profiling</div> </div> </div> <div class="field field--name-field-broad-tags field--type-entity-reference field--label-above"> <div class="field__label">ӳý tags</div> <div class="field__items"> <div class="field__item"><a href="/broad-tags/cancer-program" hreflang="en">Cancer Program</a></div> <div class="field__item"><a href="/broad-tags/cancer" hreflang="en">Cancer</a></div> </div> </div> Tue, 16 Feb 2021 14:00:00 +0000 tulrich@broadinstitute.org 763456 at Large-scale tool helps reveal function of autism spectrum disorder genes /news/large-scale-tool-helps-reveal-function-autism-spectrum-disorder-genes <span class="field field--name-title field--type-string field--label-hidden">ӳý-Novartis Cancer Cell Line Encyclopedia (CCLE)</span> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p> The Cancer Cell Line Encyclopedia (CCLE) project is an effort to conduct a detailed genetic characterization of a large panel of human cancer cell lines. The CCLE provides public access analysis and visualization of DNA copy number, mRNA expression, mutation data and more, for 1000 cancer cell lines. The Cancer Cell Line Encyclopedia (CCLE) project is an effort to conduct a detailed genetic characterization of a large panel of human cancer cell lines. The CCLE provides public access analysis and visualization of DNA copy number, mRNA expression, mutation data and more, for 1000 cancer cell lines.</p> <p> <span style="display:none;">cell line profiling</span></p> </div> <span class="field field--name-uid field--type-entity-reference field--label-hidden"> <span>By bistline@broadinstitute.org</span> </span> <span class="field field--name-created field--type-created field--label-hidden"><time datetime="2012-02-16T15:36:59-05:00" title="Thursday, February 16, 2012 - 15:36" class="datetime">February 16, 2012</time> </span> <div class="field field--name-field-software-link field--type-link field--label-above"> <div class="field__label">Link</div> <div class="field__items"> <div class="field__item"><a href="https://portals.broadinstitute.org/ccle/home">CCLE</a></div> </div> </div> <div class="field field--name-field-taxonomy-topic field--type-entity-reference field--label-above"> <div class="field__label">Topic</div> <div class="field__items"> <div class="field__item">cell lines</div> <div class="field__item">CCLE</div> <div class="field__item">cancer portals</div> <div class="field__item">cancer models</div> <div class="field__item">Cancer</div> <div class="field__item">cancer dependency</div> <div class="field__item">dependency map</div> <div class="field__item">cell line profiling</div> </div> </div> <div class="field field--name-field-broad-tags field--type-entity-reference field--label-above"> <div class="field__label">ӳý tags</div> <div class="field__items"> <div class="field__item"><a href="/broad-tags/cancer-program" hreflang="en">Cancer Program</a></div> <div class="field__item"><a href="/broad-tags/cancer" hreflang="en">Cancer</a></div> </div> </div> Thu, 03 Dec 2020 18:09:52 +0000 tulrich@broadinstitute.org 694431 at A single-cell atlas of nerve cells in the gut reveals web of connections /news/single-cell-atlas-nerve-cells-gut-reveals-web-connections <span class="field field--name-title field--type-string field--label-hidden">ӳý-Novartis Cancer Cell Line Encyclopedia (CCLE)</span> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p> The Cancer Cell Line Encyclopedia (CCLE) project is an effort to conduct a detailed genetic characterization of a large panel of human cancer cell lines. The CCLE provides public access analysis and visualization of DNA copy number, mRNA expression, mutation data and more, for 1000 cancer cell lines. The Cancer Cell Line Encyclopedia (CCLE) project is an effort to conduct a detailed genetic characterization of a large panel of human cancer cell lines. The CCLE provides public access analysis and visualization of DNA copy number, mRNA expression, mutation data and more, for 1000 cancer cell lines.</p> <p> <span style="display:none;">cell line profiling</span></p> </div> <span class="field field--name-uid field--type-entity-reference field--label-hidden"> <span>By bistline@broadinstitute.org</span> </span> <span class="field field--name-created field--type-created field--label-hidden"><time datetime="2012-02-16T15:36:59-05:00" title="Thursday, February 16, 2012 - 15:36" class="datetime">February 16, 2012</time> </span> <div class="field field--name-field-software-link field--type-link field--label-above"> <div class="field__label">Link</div> <div class="field__items"> <div class="field__item"><a href="https://portals.broadinstitute.org/ccle/home">CCLE</a></div> </div> </div> <div class="field field--name-field-taxonomy-topic field--type-entity-reference field--label-above"> <div class="field__label">Topic</div> <div class="field__items"> <div class="field__item">cell lines</div> <div class="field__item">CCLE</div> <div class="field__item">cancer portals</div> <div class="field__item">cancer models</div> <div class="field__item">Cancer</div> <div class="field__item">cancer dependency</div> <div class="field__item">dependency map</div> <div class="field__item">cell line profiling</div> </div> </div> <div class="field field--name-field-broad-tags field--type-entity-reference field--label-above"> <div class="field__label">ӳý tags</div> <div class="field__items"> <div class="field__item"><a href="/broad-tags/cancer-program" hreflang="en">Cancer Program</a></div> <div class="field__item"><a href="/broad-tags/cancer" hreflang="en">Cancer</a></div> </div> </div> Thu, 03 Sep 2020 15:49:58 +0000 kzusi@broadinstitute.org 647586 at