Kruppel-Like Transcription Factors

A Mechano-Activated Cell Reporter System as a Proxy for Flow-Dependent Endothelial Atheroprotection.

Slegtenhorst BR, Ramirez ORF, Zhang Y, Dhanerawala Z, Tullius SG, García-Cardeña G. A Mechano-Activated Cell Reporter System as a Proxy for Flow-Dependent Endothelial Atheroprotection. SLAS Discov. 2018;23(8):869-876. doi:10.1177/2472555218761101

Targeting Kruppel-like Factor 9 in Excitatory Neurons Protects against Chronic Stress-Induced Impairments in Dendritic Spines and Fear Responses.

Besnard A, Langberg T, Levinson S, et al. Targeting Kruppel-like Factor 9 in Excitatory Neurons Protects against Chronic Stress-Induced Impairments in Dendritic Spines and Fear Responses. Cell Rep. 2018;23(11):3183-3196. doi:10.1016/j.celrep.2018.05.040

Intestinal epithelial cell-specific RARα depletion results in aberrant epithelial cell homeostasis and underdeveloped immune system.

Jijon HB, Suarez-Lopez L, Diaz OE, et al. Intestinal epithelial cell-specific RARα depletion results in aberrant epithelial cell homeostasis and underdeveloped immune system. Mucosal Immunol. 2018;11(3):703-715. doi:10.1038/mi.2017.91

Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation.

Bis JC, Jian X, Kunkle BW, et al. Whole exome sequencing study identifies novel rare and common Alzheimer’s-Associated variants involved in immune response and transcriptional regulation. Mol Psychiatry. 2020;25(8):1859-1875. doi:10.1038/s41380-018-0112-7

Axonal transport of TDP-43 mRNA granules is impaired by ALS-causing mutations.

Alami NH, Smith RB, Carrasco MA, et al. Axonal transport of TDP-43 mRNA granules is impaired by ALS-causing mutations. Neuron. 2014;81(3):536-543. doi:10.1016/j.neuron.2013.12.018

PLZF, a tumor suppressor genetically lost in metastatic castration-resistant prostate cancer, is a mediator of resistance to androgen deprivation therapy.

Hsieh CL, Botta G, Gao S, et al. PLZF, a tumor suppressor genetically lost in metastatic castration-resistant prostate cancer, is a mediator of resistance to androgen deprivation therapy. Cancer Res. 2015;75(10):1944-8. doi:10.1158/0008-5472.CAN-14-3602

Control of transcription factor activity and osteoblast differentiation in mammalian cells using an evolved small-molecule-dependent intein.

Yuen CM, Rodda SJ, Vokes SA, McMahon AP, Liu DR. Control of transcription factor activity and osteoblast differentiation in mammalian cells using an evolved small-molecule-dependent intein. J Am Chem Soc. 2006;128(27):8939-46. doi:10.1021/ja062980e

Single-Cell Genomics Unveils Critical Regulators of Th17 Cell Pathogenicity.

Gaublomme JT, Yosef N, Lee Y, et al. Single-Cell Genomics Unveils Critical Regulators of Th17 Cell Pathogenicity. Cell. 2015;163(6):1400-12. doi:10.1016/j.cell.2015.11.009

Linking traits based on their shared molecular mechanisms.

Oren Y, Nachshon A, Frishberg A, Wilentzik R, Gat-Viks I. Linking traits based on their shared molecular mechanisms. Elife. 2015;4. doi:10.7554/eLife.04346

Chromatin-modifying enzymes as modulators of reprogramming.

Onder TT, Kara N, Cherry A, et al. Chromatin-modifying enzymes as modulators of reprogramming. Nature. 2012;483(7391):598-602. doi:10.1038/nature10953

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