ӳ��ý

A chemoselective strategy for late-stage functionalization of complex small molecules with polypeptides and proteins.

Cohen DT, Zhang C, Fadzen CM, et al. A chemoselective strategy for late-stage functionalization of complex small molecules with polypeptides and proteins. Nat Chem. 2019;11(1):78-85. doi:10.1038/s41557-018-0154-0

A Computationally Designed Peptide Derived from Escherichia coli as a Potential Drug Template for Antibacterial and Antibiofilm Therapies.

Cardoso MH, Cândido ES, Chan LY, et al. A Computationally Designed Peptide Derived from Escherichia coli as a Potential Drug Template for Antibacterial and Antibiofilm Therapies. ACS Infect Dis. 2018;4(12):1727-1736. doi:10.1021/acsinfecdis.8b00219

Antimicrobial peptide LL-37 and recombinant human mannose-binding lectin express distinct age- and pathogen-specific antimicrobial activity in human newborn cord blood .

Scheid A, Li N, Jeffers C, et al. Antimicrobial peptide LL-37 and recombinant human mannose-binding lectin express distinct age- and pathogen-specific antimicrobial activity in human newborn cord blood . F1000Res. 2018;7:616. doi:10.12688/f1000research.14736.1

An Immunomodulatory Peptide Confers Protection in an Experimental Candidemia Murine Model.

Freitas CG, Lima SMF, Freire MS, et al. An Immunomodulatory Peptide Confers Protection in an Experimental Candidemia Murine Model. Antimicrob Agents Chemother. 2017;61(8). doi:10.1128/AAC.02518-16

A putative Vibrio cholerae two-component system controls a conserved periplasmic protein in response to the antimicrobial peptide polymyxin B.

Matson JS, Livny J, DiRita VJ. A putative Vibrio cholerae two-component system controls a conserved periplasmic protein in response to the antimicrobial peptide polymyxin B. PLoS One. 2017;12(10):e0186199. doi:10.1371/journal.pone.0186199

Identification of Novel Cryptic Multifunctional Antimicrobial Peptides from the Human Stomach Enabled by a Computational-Experimental Platform.

Pane K, Cafaro V, Avitabile A, et al. Identification of Novel Cryptic Multifunctional Antimicrobial Peptides from the Human Stomach Enabled by a Computational-Experimental Platform. ACS Synth Biol. 2018;7(9):2105-2115. doi:10.1021/acssynbio.8b00084

Yeast-Based Synthetic Biology Platform for Antimicrobial Peptide Production.

Cao J, de la Fuente-Núñez C, Ou RW, et al. Yeast-Based Synthetic Biology Platform for Antimicrobial Peptide Production. ACS Synth Biol. 2018;7(3):896-902. doi:10.1021/acssynbio.7b00396

In silico optimization of a guava antimicrobial peptide enables combinatorial exploration for peptide design.

Porto WF, Irazazabal L, Alves ESF, et al. In silico optimization of a guava antimicrobial peptide enables combinatorial exploration for peptide design. Nat Commun. 2018;9(1):1490. doi:10.1038/s41467-018-03746-3

Portable, On-Demand Biomolecular Manufacturing.

Pardee K, Slomovic S, Nguyen PQ, et al. Portable, On-Demand Biomolecular Manufacturing. Cell. 2016;167(1):248-259.e12. doi:10.1016/j.cell.2016.09.013

Discovery and characterization of a peptide that enhances endosomal escape of delivered proteins in vitro and in vivo.

Li M, Tao Y, Shu Y, et al. Discovery and characterization of a peptide that enhances endosomal escape of delivered proteins in vitro and in vivo. J Am Chem Soc. 2015;137(44):14084-93. doi:10.1021/jacs.5b05694