News 03.22.2021 Pediatric cancers have unique genetic vulnerabilities New map of genetic dependencies points to potential drug targets for childhood cancers. Cancer Program Cancer Cancer Dependency Map Read more
News 03.11.2021 A better understanding of the immune system in kidney cancer Two research papers highlight single-cell dissection of kidney tumors to identify new immunotherapy treatments and targets Cancer Program Cancer Single cell genomics Single Cell Read more
News 02.22.2021 A call to action to build a better map of cancer’s genetic vulnerabilities Two cancer geneticists make the case for moving beyond tumor sequencing studies. Cancer Program Cancer Cancer Dependency Map Read more
News 01.04.2021 Dependency Map team releases Celligner to help match tumors and cell lines for research New computational tool uses gene expression data to measure how closely laboratory cancer models compare to real tumors Cancer Program Cancer Cancer Dependency Map DepMap Read more
News 12.15.2020 New genetic vulnerability found in upwards of a third of all cancers Genetic screens point to VPS4A and VPS4B as promising cancer drug targets Cancer Program Cancer Dependency Map Cancer DepMap Read more
News 12.09.2020 Map shows how cancer cells spread through the body The Metastasis Map can help researchers learn what causes some tumors to disseminate to different organs. Cancer Program Cancer Read more
News 12.04.2020 Native American ancestry associated with lung cancer mutations in Latin American patients Study probes interplay of genetics, ancestry, and environment in cancer risk Cancer Program Cancer Read more
News 09.14.2020 Organoids emerge as powerful tools for disease modeling and drug discovery Ó³»´«Ã½ scientists are using brain, kidney, and tumor organoids to gain new insights into disease mechanisms and therapeutic approaches. Cancer Program Stanley Center for Psychiatric Research Cancer Brain Health Rare Disease Kidney Disease Cancer Dependency Map Understanding kidney disease High-Throughput Screening Read more
News 06.04.2020 Researchers discover new member of novel drug family for ‘undruggable’ targets Findings offer a roadmap for how to build compounds to target proteins for degradation by the cell’s recycling system. Cancer Program Drug Repurposing Hub Drug Repurposing Hub Read more
News 05.22.2020 Study eyes partially-lost essential genes as possible targets in cancer Cancer cells that have lost a copy of a critical gene may be vulnerable to therapies that knock out the remaining copy Cancer Program Cancer Aggregating and harmonizing data Cancer Dependency Map Aggregating Data DepMap Read more