Expanded “connectivity map” creates more than 1.3 million gene expression profiles of drug treatment and genetic perturbation, accelerating research on small molecules and gene function.
Coinciding with the second anniversary of the breakthrough patient-driven research movement, this first of many data releases aims to accelerate progress in metastatic breast cancer research.
The ӳý Cancer Dependency Map team adds CRISPR-based data from 342 cancer cell lines to their growing catalog of genetic dependencies in cancer, and a new method for ensuring that data's accuracy.
A mutation pattern or “signature” linked to defects in two genes points to other ways an important DNA repair mechanism can be shut off in breast cancer.
A best-in-class drug screening collection with more than 3,000 clinical drugs. The Repurposing Hub information resource contains extensive curated annotations for each drug, including details about commercial sources of all compounds.