An analysis of nearly 3,800 colorectal cancer patients — the largest germline risk study for this cancer to date — reveals opportunities for improved risk screening and, possibly, treatment.
Similar mutations in the gene SPOP have completely opposite effects in prostate versus endometrial cancers. What does that mean for efforts aimed at functionally interpreting cancer genetic findings?
Expanded “connectivity map” creates more than 1.3 million gene expression profiles of drug treatment and genetic perturbation, accelerating research on small molecules and gene function.
Coinciding with the second anniversary of the breakthrough patient-driven research movement, this first of many data releases aims to accelerate progress in metastatic breast cancer research.
The ӳý Cancer Dependency Map team adds CRISPR-based data from 342 cancer cell lines to their growing catalog of genetic dependencies in cancer, and a new method for ensuring that data's accuracy.