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RNA-guided enzymes are more diverse and widespread than previously believed

Converting a pathogenic hemoglobin gene to a benign variant enables healthy blood cell production in an animal model of sickle cell disease.

Correcting the mutation that causes progeria with base editing leads to strong symptom reduction and longer lifespan in an animal model

Scientists apply the “Perturb-Seq” method to a living organism for the first time

The experimental CRISPR-based test, with further development, could potentially be used outside of labs.

A CRISPR-based test developed at MIT and the ӳ����ý can detect nearly as many cases as the standard COVID-19 diagnostic.

Inexpensive, sensitive, CRISPR-based tests diagnose two deadly viruses in settings with limited infrastructure

BE-Hive can tell which base editor performs best to repair thousands of disease-causing mutations

Cas9 can cut DNA without any guide RNA and select for cells with inactivated p53.

New CRISPR-based research tool delivers results in an hour in a one-step reaction; Researchers share protocol and kits to advance research and move toward clinical validation.