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Stimulating the liver to produce some of the signals of the thymus can reverse age-related declines in T-cell populations and enhance response to vaccination.

Researchers adapt a compact RNA-guided enzyme from bacteria for a variety of DNA editing tasks in human cells.

The programmable proteins are compact, modular, and can be directed to modify DNA in human cells.

The new genome-editing tools could lead to safer, more efficient gene therapies.

Zhang and 22 other individuals received the US’s highest honors for science and technology.

By analyzing bacterial data, researchers have discovered thousands of rare new CRISPR systems that have a range of functions and could enable gene editing, diagnostics, and more.

The first RNA-guided DNA-cutting enzyme found in eukaryotes, Fanzor could one day be harnessed to edit DNA more precisely than CRISPR/Cas systems.

With further development, the programmable system could be used in a range of applications including gene therapy and cancer therapy.