By surveying gene expression in over 53,000 cells from the small intestine, researchers have created a rich reference for understanding the biology of inflammatory bowel disease and food allergies, among other conditions.
DroNc-Seq — a technology that merges single-nucleus RNA sequencing with microfluidics — brings new scale to gene expression studies in complex tissues.
Members of the Klarman Cell Observatory at the Ó³»´«Ã½ and the (CCPM) at the Dana-Farber Cancer Institute, Brigham and Women’s Hospital, and the Ó³»´«Ã½ have embarked on an ambitious effort to use single-cell genome analysis to explore the diverse cellular environments of cancer tumors in finer detail than ever before.