New clues from canine cancer

Dogs, like humans, can develop blood system cancers that share similarities with human blood cancer. A team of scientists, led by the Ó³»­´«Ã½'s Kerstin Lindblad-Toh and co-senior authors from North Carolina State University and the University of Minnesota, recently conducted a genome-wide association study in dogs to identify genetic risk factors for hematologic cancer, focusing on two malignancies and uncovering two shared genomic loci that predispose dogs to both diseases. The results, appearing in , suggest that the interaction between the immune system and malignant cells plays a role in hematologic tumorigenesis.