Pancreatic cancer is the tenth most common cancer in the United States, but the fourth most common cause of cancer death. This disparity is due, in part, to the disease’s elusive nature. Because the pancreas is located deep in the abdomen, symptoms often present only after cancer has spread to other places in the body. But this week, a team of researchers from the ӳý, , MIT, and elsewhere reported the discovery of metabolic changes that indicate early development of the disease.