Challenging Roadblocks to Cancer Cure.

Cancer Res
Authors
Abstract

The Pezcoller Symposium in Trento, Italy, June 2015, focused entirely on the question of why advanced cancer cure is so uncommon despite the extraordinarily rapid growth of invaluable therapeutic information. Participants were asked to define and to critically evaluate real and potential obstacles to permanent disease eradication. High-level concepts on potential road blocks to cures as well as opportunities for intervention in diverse areas of investigation ranging from genomic alterations to metabolism, microenvironment, immunity, and mechanotransduction were discussed. Provocative concepts and novel therapeutic avenues were proposed. What follows is a critical analysis of the highlights of this meeting. Cancer Res; 76(17); 4924-30. ©2016 AACR.

Year of Publication
2016
Journal
Cancer Res
Volume
76
Issue
17
Pages
4924-30
Date Published
2016 Sep 01
ISSN
1538-7445
DOI
10.1158/0008-5472.CAN-16-1443
PubMed ID
27520451
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