Single cell RNA-seq highlights a role for a partial EMT in head and neck cancer.

Mol Cell Oncol
Authors
Abstract

Studies in single cell transcriptomics have significantly expanded our understanding of tumor biology, including recent analyses in head and neck squamous cell carcinoma. Here, we focus on the role of a partial epithelial-to-mesenchymal (EMT) program in these tumors, with discussion of its dynamics, regulation, and implications for diagnostic and therapeutic approaches.

Year of Publication
2018
Journal
Mol Cell Oncol
Volume
5
Issue
3
Pages
e1448244
Date Published
2018
ISSN
2372-3556
DOI
10.1080/23723556.2018.1448244
PubMed ID
30250901
PubMed Central ID
PMC6149805
Links
Grant list
K08 CA237732 / CA / NCI NIH HHS / United States