Type I Interferons Interfere with Liver Glucose Metabolism.

Cell Metab
Authors
Abstract

The specific immunological components linking metabolic stresses to liver inflammation and systemic metabolic pathologies in obesity are not entirely known. A recent study (Ghazarian et al., 2017) reveals that obesity-induced type I interferon signaling drives the accumulation and activation of intrahepatic CD8 T cells, leading to systemic metabolic deterioration.

Year of Publication
2017
Journal
Cell Metab
Volume
25
Issue
6
Pages
1211-1212
Date Published
2017 Jun 06
ISSN
1932-7420
DOI
10.1016/j.cmet.2017.05.009
PubMed ID
28591628
Links