LAVAA: a lightweight association viewer across ailments.
| Authors | |
| Abstract | MOTIVATION: Biobank scale genetic associations results over thousands of traits can be difficult to visualize and navigate.RESULTS: We have created LAVAA, a visualization web-application to generate genetic volcano plots for simultaneously considering the -value, effect size, case counts, trait class and fine-mapping posterior probability at a single-nucleotide polymorphism (SNP) across a range of traits from a large set of genome-wide association study. We find that user interaction with association results in LAVAA can enrich and enhance the biological interpretation of individual loci.AVAILABILITY AND IMPLEMENTATION: LAVAA is available as a stand-alone web service () and will be available in future releases of the finngen.fi website starting with release 10 in late 2023. |
| Year of Publication | 2023
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| Journal | Bioinformatics advances
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| Volume | 3
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| Issue | 1
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| Pages | vbad018
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| Date Published | 12/2023
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| ISSN | 2635-0041
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| DOI | 10.1093/bioadv/vbad018
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| PubMed ID | 36908397
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