LAVAA: a lightweight association viewer across ailments.

Bioinformatics advances
Authors
Abstract

MOTIVATION: Biobank scale genetic associations results over thousands of traits can be difficult to visualize and navigate.RESULTS: We have created LAVAA, a visualization web-application to generate genetic volcano plots for simultaneously considering the -value, effect size, case counts, trait class and fine-mapping posterior probability at a single-nucleotide polymorphism (SNP) across a range of traits from a large set of genome-wide association study. We find that user interaction with association results in LAVAA can enrich and enhance the biological interpretation of individual loci.AVAILABILITY AND IMPLEMENTATION: LAVAA is available as a stand-alone web service () and will be available in future releases of the finngen.fi website starting with release 10 in late 2023.

Year of Publication
2023
Journal
Bioinformatics advances
Volume
3
Issue
1
Pages
vbad018
Date Published
12/2023
ISSN
2635-0041
DOI
10.1093/bioadv/vbad018
PubMed ID
36908397
Links