Proximity labeling of endogenous protein interactions enabled by directed evolution.

Trends in biotechnology
Authors
Abstract

Enhanced ascorbate peroxidase 2 (APEX2) is a protein generated with directed evolution by Lam et al. that has transformed our understanding of subcellular entities and phenomena. The rapid kinetics of this engineered protein highlights the power of directed evolution to expand the molecular toolkit for biologists.

Year of Publication
2023
Journal
Trends in biotechnology
Volume
41
Issue
3
Pages
301-303
Date Published
03/2023
ISSN
1879-3096
DOI
10.1016/j.tibtech.2023.01.012
PubMed ID
36710130
Links