A simple, time- and cost-effective, high-throughput depletion strategy for deep plasma proteomics.
Science advances
| Authors | |
| Abstract | We introduce a cost-effective, robust high-throughput-compatible plasma depletion method enabling in-depth profiling of plasma that detects >1300 proteins per run with a throughput of 60 samples per day. The method has been fully validated by processing >3000 samples with no apparent batch effect at a cost for the depletion step of ~$2.5 per sample. |
| Year of Publication | 2023
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| Journal | Science advances
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| Volume | 9
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| Issue | 13
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| Pages | eadf9717
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| Date Published | 03/2023
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| ISSN | 2375-2548
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| DOI | 10.1126/sciadv.adf9717
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| PubMed ID | 36989362
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