AliGater: a framework for the development of bioinformatic pipelines for large-scale, high-dimensional cytometry data.
Bioinformatics advances
| Authors | |
| Abstract | MOTIVATION: AliGater is an open-source framework to accelerate the development of bioinformatic pipelines for the analysis of large-scale, high-dimensional flow cytometry data. AliGater provides a Python package for automatic feature extraction workflows, as well as building blocks to construct analysis pipelines.RESULTS: We illustrate the use of AliGater in a high-resolution flow cytometry-based genome-wide association study on 46 immune cell populations in 14 288 individuals.AVAILABILITY AND IMPLEMENTATION: Source code and documentation at and . |
| Year of Publication | 2023
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| Journal | Bioinformatics advances
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| Volume | 3
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| Issue | 1
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| Pages | vbad103
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| Date Published | 12/2023
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| ISSN | 2635-0041
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| DOI | 10.1093/bioadv/vbad103
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| PubMed ID | 37600847
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