Getting an aMPLe grasp on hematopoiesis.

Cell
Authors
Abstract

Hematopoiesis requires balance between self-renewal of stem cells and differentiation into mature blood cells, orchestrated by pathways such as thrombopoietin signaling. In this issue of Cell, Tsutsumi et al. report the structure of the thrombopoietin ligand-receptor complex and demonstrate the potential to decouple its roles in self-renewal and hematopoietic differentiation.

Year of Publication
2023
Journal
Cell
Volume
186
Issue
19
Pages
4005-4006
Date Published
09/2023
ISSN
1097-4172
DOI
10.1016/j.cell.2023.08.015
PubMed ID
37714132
Links