KRAS Wild-Type Pancreatic Cancer: Decoding Genomics, Unlocking Therapeutic Potential.

Clinical cancer research : an official journal of the American Association for Cancer Research
Authors
Abstract

In a landscape dominated by pivotal KRAS mutations, there has been limited exploration of KRAS wild-type pancreatic cancer. A recent study highlights other mitogen-activated kinase pathway alterations as alternative drivers in these tumors, which holds the key to unlocking a realm of targeted therapies for patients with this understudied cancer subtype. See related article by Singh et al., p. 4627.

Year of Publication
2023
Journal
Clinical cancer research : an official journal of the American Association for Cancer Research
Volume
29
Issue
22
Pages
4527-4529
Date Published
11/2023
ISSN
1557-3265
DOI
10.1158/1078-0432.CCR-23-2221
PubMed ID
37695631
Links