Blood and bones: Mechanical cues and Hippo signaling drive vascular invasion during limb formation.

Developmental cell
Authors
Abstract

Although mechanical cues are known to influence the postnatal skeleton, the impact of bone cell mechano-transduction on early skeletal development remains less clear. In this issue of Developmental Cell, Collins et al. (2023) report that YAP/TAZ deletion in osteoblast precursors reduces Cxcl12 expression, leading to defects in bone vascularization.

Year of Publication
2024
Journal
Developmental cell
Volume
59
Issue
2
Pages
173-174
Date Published
01/2024
ISSN
1878-1551
DOI
10.1016/j.devcel.2023.12.008
PubMed ID
38262346
Links