Understanding Mechanisms of Response to CAR T-cell Therapy through Single-Cell Sequencing: Insights and Challenges.
Blood cancer discovery
| Authors | |
| Abstract | Single-cell RNA sequencing has emerged as a powerful technique to understand the molecular features of chimeric antigen receptor (CAR) T cells that associate with clinical outcomes. Here we discuss the common themes that have emerged from across single-cell studies of CAR T-cell therapy, and summarize the challenges in interpreting this complex data type. |
| Year of Publication | 2024
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| Journal | Blood cancer discovery
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| Pages | OF1-OF4
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| Date Published | 02/2024
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| ISSN | 2643-3249
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| DOI | 10.1158/2643-3230.BCD-23-0212
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| PubMed ID | 38324393
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