scX: a user-friendly tool for scRNAseq exploration.
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Abstract | MOTIVATION: Single-cell RNA sequencing (scRNAseq) has transformed our ability to explore biological systems. Nevertheless, proficient expertise is essential for handling and interpreting the data.RESULTS: In this article, we present scX, an R package built on the Shiny framework that streamlines the analysis, exploration, and visualization of single-cell experiments. With an interactive graphic interface, implemented as a web application, scX provides easy access to key scRNAseq analyses, including marker identification, gene expression profiling, and differential gene expression analysis. Additionally, scX seamlessly integrates with commonly used single-cell Seurat and SingleCellExperiment R objects, resulting in efficient processing and visualization of varied datasets. Overall, scX serves as a valuable and user-friendly tool for effortless exploration and sharing of single-cell data, simplifying some of the complexities inherent in scRNAseq analysis.AVAILABILITY AND IMPLEMENTATION: Source code can be downloaded from . A docker image is available from dockerhub as chernolabs/scx. |
Year of Publication | 2024
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Journal | Bioinformatics advances
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Volume | 4
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Issue | 1
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Pages | vbae062
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Date Published | 12/2024
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ISSN | 2635-0041
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DOI | 10.1093/bioadv/vbae062
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PubMed ID | 38779177
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