Tertiary lymphoid structure formation: A matter of tumor-immune co-evolution.

Molecular immunology
Authors
Keywords
Abstract

The immune make-up of human tumors is dynamic over the course of cancer progression. However, what factors drive spatiotemporal changes in the tumor-immune landscape is not well-known. In issue 3 of Cell Reports Medicine, Liu, You, Lan and Ren et al. demonstrate that the development of tertiary lymphoid structures (TLSs) is a stepwise process that co-occurs with tumor progression in patients with lung adenocarcinoma (LUAD).

Year of Publication
2024
Journal
Molecular immunology
Volume
175
Pages
143-145
Date Published
10/2024
ISSN
1872-9142
DOI
10.1016/j.molimm.2024.09.012
PubMed ID
39383568
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