Distance matters: How protein regulators facilitate enhancer-promoter interactions and transcription.
Cell genomics
| Authors | |
| Abstract | Cohesin, transcription factors (TFs), and mediator complex components regulate gene expression partly by regulating enhancer-promoter (E-P) communication. A new study combined E-P distance-controlled reporter screens with the inhibition or degradation of regulatory proteins and uncovered a distance-dependent effect across cohesin, TFs, and mediator complex components. |
| Year of Publication | 2025
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| Journal | Cell genomics
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| Volume | 5
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| Issue | 3
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| Pages | 100817
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| Date Published | 03/2025
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| ISSN | 2666-979X
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| DOI | 10.1016/j.xgen.2025.100817
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| PubMed ID | 40081334
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