Parts and ICRAFTs: Finding new immunotherapy targets.
Immunity
| Authors | |
| Abstract | CRISPR screens are widely utilized to identify genes that regulate immune function or mediate sensitivity of cancer cells to immune attack. In this issue of Immunity, Zeng et al. present a computational framework for uncovering gene targets with dual function in both cancer and immune cells and nominate TNFAIP3 as a synergistic target whose ablation strongly elicits an antitumor response. |
| Year of Publication | 2025
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| Journal | Immunity
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| Volume | 58
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| Issue | 3
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| Pages | 529-531
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| Date Published | 03/2025
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| ISSN | 1097-4180
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| DOI | 10.1016/j.immuni.2025.02.016
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| PubMed ID | 40073844
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