Single-cell Epigenomic Profiling with High-throughput Droplet scChIP-seq.
Methods in molecular biology (Clifton, N.J.)
| Authors | |
| Keywords | |
| Abstract | Our high-throughput scChIP-seq approach combines droplet microfluidics with single-cell DNA barcoding to study the heterogeneity of epigenomes (H3K27me3, H3K4me3, H3K27Ac, H3K4me1) in a cellular population of several thousand cells with a coverage of up to 10,000 unique loci per cell. |
| Year of Publication | 2025
|
| Journal | Methods in molecular biology (Clifton, N.J.)
|
| Volume | 2919
|
| Pages | 213-239
|
| Date Published | 12/2025
|
| ISSN | 1940-6029
|
| DOI | 10.1007/978-1-0716-4486-7_12
|
| PubMed ID | 40257565
|
| Links |