Active on demand: A precision prodrug strategy against drug-resistant Gram-negative pathogens.
Cell host & microbe
| Authors | |
| Abstract | In a recent issue of Science Translational Medicine, Xie et al. introduce a host defense peptide-mimicking prodrug that activates selectively at acidic infection sites, clearing Gram-negative pathogens and biofilms without inducing resistance-advancing precision antibiotic therapy. |
| Year of Publication | 2025
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| Journal | Cell host & microbe
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| Volume | 33
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| Issue | 8
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| Pages | 1315-1317
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| Date Published | 08/2025
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| ISSN | 1934-6069
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| DOI | 10.1016/j.chom.2025.07.013
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| PubMed ID | 40812184
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