The World Needs a PEPP Policy that Addresses Biosafety Loopholes Highlighted by the COVID-19 Pandemic.

Applied biosafety : journal of the American Biological Safety Association
Authors
Keywords
Abstract

The new U.S. government policy for oversight of dual-use research of concern and pathogens with enhanced pandemic potential (PEPP) focuses on federally funded research projects that are predicted by the funding applicant to have a nontrivial likelihood of generating a PEPP. This leaves a considerable gap in oversight of nonfederally funded work and research on novel pathogens. The prediction of pandemic risk arising from novel experiments is difficult even for multidisciplinary teams of experts, and a self-reporting system is inadequate as evidenced by past incidents. Creating an independent organization for oversight, inspection, and investigation of research projects regardless of funding source will ensure consistency and transparency in policy implementation and help to build knowledge and best practices for mitigating the risks of accidental outbreaks.

Year of Publication
2025
Journal
Applied biosafety : journal of the American Biological Safety Association
Volume
30
Issue
2
Pages
146-150
Date Published
06/2025
ISSN
2470-1246
DOI
10.1089/apb.2024.0041
PubMed ID
40548086
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