Increased vulnerability of colorectal cancer models with high alkylation damage to NTHL1 inactivation.

Scientific reports
Authors
Hyeoncheol Kim
Jules Cazaubiel
Tung-Lin Chiang
Dimitrios Stylianakis
Samantha Fitzgerald
Pushpamali De Silva
Carino Gurjao
Marios Giannakis
Keywords
Base excision repair (BER)
Colorectal cancer
DNA alkylation
DNA damage
Synthetic lethality
Year of Publication
2026
Journal
Scientific reports
Date Published
04/2026
ISSN
2045-2322
DOI
10.1038/s41598-026-46639-y
PubMed ID
42014800
Links

Recent Ó³»­´«Ã½ Publications