Immune Cell Intolerance for Excess Cholesterol.

Immunity
Authors
Abstract

Chronic metabolic challenges have severe consequences on physiological systems. In this issue of Immunity, Ito et al. (2016) show that defects in cholesterol metabolism in CD11c(+) immune cells result in impaired antigen presentation and ultimately in autoimmune disease.

Year of Publication
2016
Journal
Immunity
Volume
45
Issue
6
Pages
1186-1188
Date Published
2016 Dec 20
ISSN
1097-4180
DOI
10.1016/j.immuni.2016.12.006
PubMed ID
28002726
Links