Nucleic-acid-templated synthesis as a model system for ancient translation.
Curr Opin Chem Biol
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| Abstract | The translation of nucleic acids into synthetic structures with expanded functional potential has been the subject of considerable research, with applications including small-molecule and polymer evolution, reaction discovery and sensing. Here, we review properties of nucleic-acid-templated synthesis in the context of requirements for prebiotic translation. This analysis highlights the chemical possibilities of ancient translation systems, as well as challenges that these systems may have faced. |
| Year of Publication | 2004
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| Journal | Curr Opin Chem Biol
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| Volume | 8
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| Issue | 6
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| Pages | 645-53
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| Date Published | 2004 Dec
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| ISSN | 1367-5931
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| DOI | 10.1016/j.cbpa.2004.09.003
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| PubMed ID | 15556410
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| Grant list | R01GM065865 / GM / NIGMS NIH HHS / United States
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