BioBitsâ„¢ Bright: A fluorescent synthetic biology education kit.
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| Abstract | Synthetic biology offers opportunities for experiential educational activities at the intersection of the life sciences, engineering, and design. However, implementation of hands-on biology activities in classrooms is challenging because of the need for specialized equipment and expertise to grow living cells. We present BioBitsâ„¢ Bright, a shelf-stable, just-add-water synthetic biology education kit with easy visual outputs enabled by expression of fluorescent proteins in freeze-dried, cell-free reactions. We introduce activities and supporting curricula for teaching the central dogma, tunable protein expression, and design-build-test cycles and report data generated by K-12 teachers and students. We also develop inexpensive incubators and imagers, resulting in a comprehensive kit costing |
| Year of Publication | 2018
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| Journal | Sci Adv
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| Volume | 4
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| Issue | 8
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| Pages | eaat5107
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| Date Published | 2018 08
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| ISSN | 2375-2548
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| DOI | 10.1126/sciadv.aat5107
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| PubMed ID | 30083609
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| PubMed Central ID | PMC6070313
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