Exploring the Protein Universe via Highly Accurate Structural Predictions
Seoul National University
Please note: this talk will be held in the Ó³»´«Ã½ Auditorium (415 Main St.)
Understanding the relationships and functions of proteins at a global scale is essential for unlocking new biological insights. Advances in next-generation structure predictors such as AlphaFold2 and ESMfold have yielded an unprecedented volume of protein structures, providing a powerful foundation for this challenge. In this talk, I will show how our computational methods MMseqs2, Foldseek and Folddisco enable extraction of biological insights from protein sequences and structures at nearly billion-scale, accelerating the way we explore protein function and evolution.