Midsummer Nights' Science: Progress in psychiatric genetics
To find genes that underlie traits or diseases, scientists often conduct genome-wide association studies (GWAS). GWAS scan the entire genome for common variants to highlight areas likely to harbor influential genes. While researchers long debated whether this was a useful approach to studying psychiatric disease, recent GWAS have revealed vital information about genetic variations that may be associated with these disorders.
In this second installment of the Ó³»´«Ã½'s 2014 Midsummer Nights' Science lecture series, Benjamin Neale described what he and his colleagues have learned from their genome-wide association and next generation sequencing efforts, with a particular focus on schizophrenia and autism.