Body Mass Index

Obesity and Weight Gain Since Early Adulthood Are Associated With a Lower Risk of Microscopic Colitis.

Liu PH, Burke KE, Ananthakrishnan AN, et al. Obesity and Weight Gain Since Early Adulthood Are Associated With a Lower Risk of Microscopic Colitis. Clin Gastroenterol Hepatol. 2019;17(12):2523-2532.e1. doi:10.1016/j.cgh.2018.11.057

The SLC16A11 risk haplotype is associated with decreased insulin action, higher transaminases and large-size adipocytes.

Almeda-Valdes P, Velasco DVG, Campos OA, et al. The SLC16A11 risk haplotype is associated with decreased insulin action, higher transaminases and large-size adipocytes. Eur J Endocrinol. 2019;180(2):99-107. doi:10.1530/EJE-18-0677

Diet quality and genetic association with body mass index: results from 3 observational studies.

Ding M, Ellervik C, Huang T, et al. Diet quality and genetic association with body mass index: results from 3 observational studies. Am J Clin Nutr. 2018;108(6):1291-1300. doi:10.1093/ajcn/nqy203

Association of Obesity With Risk of Early-Onset Colorectal Cancer Among Women.

Liu PH, Wu K, Ng K, et al. Association of Obesity With Risk of Early-Onset Colorectal Cancer Among Women. JAMA Oncol. 2019;5(1):37-44. doi:10.1001/jamaoncol.2018.4280

Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.

Ligthart S, Vaez A, Võsa U, et al. Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders. Am J Hum Genet. 2018;103(5):691-706. doi:10.1016/j.ajhg.2018.09.009

Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps.

Mahajan A, Taliun D, Thurner M, et al. Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps. Nat Genet. 2018;50(11):1505-1513. doi:10.1038/s41588-018-0241-6

Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry.

Pulit SL, Stoneman C, Morris AP, et al. Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry. Hum Mol Genet. 2019;28(1):166-174. doi:10.1093/hmg/ddy327

Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity.

Joshi PK, Pirastu N, Kentistou KA, et al. Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity. Nat Commun. 2017;8(1):910. doi:10.1038/s41467-017-00934-5

Heritability enrichment of specifically expressed genes identifies disease-relevant tissues and cell types.

Finucane HK, Reshef YA, Anttila V, et al. Heritability enrichment of specifically expressed genes identifies disease-relevant tissues and cell types. Nat Genet. 2018;50(4):621-629. doi:10.1038/s41588-018-0081-4

CNV-association meta-analysis in 191,161 European adults reveals new loci associated with anthropometric traits.

Macé A, Tuke MA, Deelen P, et al. CNV-association meta-analysis in 191,161 European adults reveals new loci associated with anthropometric traits. Nat Commun. 2017;8(1):744. doi:10.1038/s41467-017-00556-x

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