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Tracking the origin, development, and differentiation of hematopoietic stem cells.

Dharampuriya PR, Scapin G, Wong C, Wagner J, Cillis JL, Shah DI. Tracking the origin, development, and differentiation of hematopoietic stem cells. Curr Opin Cell Biol. 2017;49:108-115. doi:10.1016/j.ceb.2018.01.002

Reconstruction of complex single-cell trajectories using CellRouter.

da Rocha EL, Rowe G, Lundin V, et al. Reconstruction of complex single-cell trajectories using CellRouter. Nat Commun. 2018;9(1):892. doi:10.1038/s41467-018-03214-y

Dendritic Cell PD-L1 Limits Autoimmunity and Follicular T Cell Differentiation and Function.

Sage PT, Schildberg FA, Sobel RA, Kuchroo VK, Freeman GJ, Sharpe AH. Dendritic Cell PD-L1 Limits Autoimmunity and Follicular T Cell Differentiation and Function. J Immunol. 2018;200(8):2592-2602. doi:10.4049/jimmunol.1701231

Dissecting the Functional Consequences of De Novo DNA Methylation Dynamics in Human Motor Neuron Differentiation and Physiology.

Ziller MJ, Ortega JA, Quinlan KA, et al. Dissecting the Functional Consequences of De Novo DNA Methylation Dynamics in Human Motor Neuron Differentiation and Physiology. Cell Stem Cell. 2018;22(4):559-574.e9. doi:10.1016/j.stem.2018.02.012

An inactivating mutation in the histone deacetylase SIRT6 causes human perinatal lethality.

Ferrer CM, Alders M, Postma AV, et al. An inactivating mutation in the histone deacetylase SIRT6 causes human perinatal lethality. Genes Dev. 2018;32(5-6):373-388. doi:10.1101/gad.307330.117

Fas Promotes T Helper 17 Cell Differentiation and Inhibits T Helper 1 Cell Development by Binding and Sequestering Transcription Factor STAT1.

Horste GMZ, Przybylski D, Schramm MA, et al. Fas Promotes T Helper 17 Cell Differentiation and Inhibits T Helper 1 Cell Development by Binding and Sequestering Transcription Factor STAT1. Immunity. 2018;48(3):556-569.e7. doi:10.1016/j.immuni.2018.03.008

Changes in the Synaptic Proteome in Tauopathy and Rescue of Tau-Induced Synapse Loss by C1q Antibodies.

Dejanovic B, Huntley MA, De Mazière A, et al. Changes in the Synaptic Proteome in Tauopathy and Rescue of Tau-Induced Synapse Loss by C1q Antibodies. Neuron. 2018;100(6):1322-1336.e7. doi:10.1016/j.neuron.2018.10.014

Report of the Key Opinion Leaders Meeting on Stem Cell-derived Beta Cells.

Odorico J, Markmann J, Melton D, et al. Report of the Key Opinion Leaders Meeting on Stem Cell-derived Beta Cells. Transplantation. 2018;102(8):1223-1229. doi:10.1097/TP.0000000000002217

Human-Specific NOTCH2NL Genes Affect Notch Signaling and Cortical Neurogenesis.

Fiddes IT, Lodewijk GA, Mooring M, et al. Human-Specific NOTCH2NL Genes Affect Notch Signaling and Cortical Neurogenesis. Cell. 2018;173(6):1356-1369.e22. doi:10.1016/j.cell.2018.03.051

The RNA-binding protein YBX1 regulates epidermal progenitors at a posttranscriptional level.

Kwon E, Todorova K, Wang J, et al. The RNA-binding protein YBX1 regulates epidermal progenitors at a posttranscriptional level. Nat Commun. 2018;9(1):1734. doi:10.1038/s41467-018-04092-0