Charlton J, Downing TL, Smith ZD, et al. Global delay in nascent strand DNA methylation. Nat Struct Mol Biol. 2018;25(4):327-332. doi:10.1038/s41594-018-0046-4
Gilles ME, Hao L, Huang L, et al. Personalized RNA Medicine for Pancreatic Cancer. Clin Cancer Res. 2018;24(7):1734-1747. doi:10.1158/1078-0432.CCR-17-2733
Herrera KNG, Zaganjor E, Ishikawa Y, et al. Small-Molecule Screen Identifies De Novo Nucleotide Synthesis as a Vulnerability of Cells Lacking SIRT3. Cell Rep. 2018;22(8):1945-1955. doi:10.1016/j.celrep.2018.01.076
Minton DR, Nam M, McLaughlin DJ, et al. Serine Catabolism by SHMT2 Is Required for Proper Mitochondrial Translation Initiation and Maintenance of Formylmethionyl-tRNAs. Mol Cell. 2018;69(4):610-621.e5. doi:10.1016/j.molcel.2018.01.024
Shee K, Yang W, Hinds JW, et al. Therapeutically targeting tumor microenvironment-mediated drug resistance in estrogen receptor-positive breast cancer. J Exp Med. 2018;215(3):895-910. doi:10.1084/jem.20171818
Goel S, DeCristo MJ, Watt AC, et al. CDK4/6 inhibition triggers anti-tumour immunity. Nature. 2017;548(7668):471-475. doi:10.1038/nature23465
Zimmer M, Ebert BL, Neil C, et al. Small-molecule inhibitors of HIF-2a translation link its 5’UTR iron-responsive element to oxygen sensing. Mol Cell. 2008;32(6):838-48. doi:10.1016/j.molcel.2008.12.004
Tang YC, Yuwen H, Wang K, et al. Aneuploid Cell Survival Relies upon Sphingolipid Homeostasis. Cancer Res. 2017;77(19):5272-5286. doi:10.1158/0008-5472.CAN-17-0049
Goods BA, Hernandez AL, Lowther DE, et al. Functional differences between PD-1+ and PD-1- CD4+ effector T cells in healthy donors and patients with glioblastoma multiforme. PLoS One. 2017;12(9):e0181538. doi:10.1371/journal.pone.0181538
Bunse L, Pusch S, Bunse T, et al. Suppression of antitumor T cell immunity by the oncometabolite (R)-2-hydroxyglutarate. Nat Med. 2018;24(8):1192-1203. doi:10.1038/s41591-018-0095-6