Boiarsky R, Haradhvala NJ, Alberge JB, et al. Single cell characterization of myeloma and its precursor conditions reveals transcriptional signatures of early tumorigenesis. Nat Commun. 2022;13(1):7040. doi:10.1038/s41467-022-33944-z
Sebastián C, Ferrer C, Serra M, et al. A non-dividing cell population with high pyruvate dehydrogenase kinase activity regulates metabolic heterogeneity and tumorigenesis in the intestine. Nat Commun. 2022;13(1):1503. doi:10.1038/s41467-022-29085-y
Ritsma L, Dey-Guha I, Talele N, et al. Integrin β1 activation induces an anti-melanoma host response. PLoS One. 2017;12(4):e0175300. doi:10.1371/journal.pone.0175300
Ramanathan A, Wang C, Schreiber SL. Perturbational profiling of a cell-line model of tumorigenesis by using metabolic measurements. Proc Natl Acad Sci U S A. 2005;102(17):5992-7. doi:10.1073/pnas.0502267102
Chalmers ZR, Connelly CF, Fabrizio D, et al. Analysis of 100,000 human cancer genomes reveals the landscape of tumor mutational burden. Genome Med. 2017;9(1):34. doi:10.1186/s13073-017-0424-2
Miller E, Yang J, DeRan M, et al. Identification of serum-derived sphingosine-1-phosphate as a small molecule regulator of YAP. Chem Biol. 2012;19(8):955-62. doi:10.1016/j.chembiol.2012.07.005
Raj L, Ide T, Gurkar AU, et al. Selective killing of cancer cells by a small molecule targeting the stress response to ROS. Nature. 2011;475(7355):231-4. doi:10.1038/nature10167
Kwon HJ, Owa T, Hassig CA, Shimada J, Schreiber SL. Depudecin induces morphological reversion of transformed fibroblasts via the inhibition of histone deacetylase. Proc Natl Acad Sci U S A. 1998;95(7):3356-61.
Saji S, Kawakami M, Hayashi SI, et al. Significance of HDAC6 regulation via estrogen signaling for cell motility and prognosis in estrogen receptor-positive breast cancer. Oncogene. 2005;24(28):4531-9. doi:10.1038/sj.onc.1208646
Shimada J, Kwon HJ, Sawamura M, Schreiber SL. Synthesis and cellular characterization of the detransformation agent, (-)-depudecin. Chem Biol. 1995;2(8):517-25.