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      1. Carlos Slim Center for Health Research The Slim Center aims to bring the benefits of genomics-driven medicine to Latin America, gleaning new insights into diseases with relevance to the region.
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      3. Klarman Cell Observatory The Klarman Cell Observatory is systematically defining mammalian cellular circuits, how they work together to create tissues and organs, and are perturbed to cause disease.
      4. Merkin Institute for Transformative Technologies in Healthcare The Merkin Institute is supporting early-stage ideas aimed at advancing powerful technological approaches for improving how we understand and treat disease.
      5. Novo Nordisk Foundation Center for Genomic Mechanisms of Disease This center is developing new paradigms and technologies to scale the discovery of biological mechanisms of common, complex diseases, by facilitating close collaborations between the Ó³»­´«Ã½ and the Danish research community.
      6. Eric and Wendy Schmidt Center The EWSC is catalyzing a new field of interdisciplinary research at the intersection of data science and life science, aimed at improving human health.
      7. Stanley Center for Psychiatric Research The Stanley Center aims to reduce the burden of serious mental illness by contributing new insights into pathogenesis, identifying biomarkers, and paving the way toward new treatments.
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      1. Art and science connection Explore the connection between art and science and how we bring together artists and Ó³»­´«Ã½ scientists through our artist-in-residence program, gallery exhibitions, and ongoing public conversations.
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Global nucleosome occupancy in yeast.
Bernstein BE, Liu CL, Humphrey EL, Perlstein EO, Schreiber SL. Global nucleosome occupancy in yeast. Genome Biol. 2004;5(9):R62. doi:10.1186/gb-2004-5-9-r62
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Molecular sled sequences are common in mammalian proteins.
Xiong K, Blainey PC. Molecular sled sequences are common in mammalian proteins. Nucleic Acids Res. 2016;44(5):2266-73. doi:10.1093/nar/gkw035
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Comparative genomics and prediction of conditionally dispensable sequences in legume-infecting Fusarium oxysporum formae speciales facilitates identification of candidate effectors.
Williams AH, Sharma M, Thatcher LF, et al. Comparative genomics and prediction of conditionally dispensable sequences in legume-infecting Fusarium oxysporum formae speciales facilitates identification of candidate effectors. BMC Genomics. 2016;17:191. doi:10.1186/s12864-016-2486-8
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The Fusarium graminearum genome reveals a link between localized polymorphism and pathogen specialization.
Cuomo CA, Güldener U, Xu JR, et al. The Fusarium graminearum genome reveals a link between localized polymorphism and pathogen specialization. Science. 2007;317(5843):1400-2. doi:10.1126/science.1143708
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Expansion of Interstitial Telomeric Sequences in Yeast.
Aksenova AY, Han G, Shishkin AA, Volkov KV, Mirkin SM. Expansion of Interstitial Telomeric Sequences in Yeast. Cell Rep. 2015;13(8):1545-51. doi:10.1016/j.celrep.2015.10.023
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Short-term temporal variability in airborne bacterial and fungal populations.
Fierer N, Liu Z, Rodríguez-Hernández M, Knight R, Henn M, Hernandez MT. Short-term temporal variability in airborne bacterial and fungal populations. Appl Environ Microbiol. 2008;74(1):200-7. doi:10.1128/AEM.01467-07
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Genome Evolution and Innovation across the Four Major Lineages of Cryptococcus gattii.
Farrer RA, Desjardins CA, Sakthikumar S, et al. Genome Evolution and Innovation across the Four Major Lineages of Cryptococcus gattii. MBio. 2015;6(5):e00868-15. doi:10.1128/mBio.00868-15
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Analysis of the genome and transcriptome of Cryptococcus neoformans var. grubii reveals complex RNA expression and microevolution leading to virulence attenuation.
Janbon G, Ormerod KL, Paulet D, et al. Analysis of the genome and transcriptome of Cryptococcus neoformans var. grubii reveals complex RNA expression and microevolution leading to virulence attenuation. PLoS Genet. 2014;10(4):e1004261. doi:10.1371/journal.pgen.1004261
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Linkage to the mating-type locus across the genus Microbotryum: insights into nonrecombining chromosomes.
Petit E, Giraud T, de Vienne DM, et al. Linkage to the mating-type locus across the genus Microbotryum: insights into nonrecombining chromosomes. Evolution. 2012;66(11):3519-33. doi:10.1111/j.1558-5646.2012.01703.x
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Comparative genome analysis of Trichophyton rubrum and related dermatophytes reveals candidate genes involved in infection.
Martinez DA, Oliver BG, Gräser Y, et al. Comparative genome analysis of Trichophyton rubrum and related dermatophytes reveals candidate genes involved in infection. MBio. 2012;3(5):e00259-12. doi:10.1128/mBio.00259-12
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In March of 2020, Ó³»­´«Ã½ converted a clinical genetics processing lab into a large-scale COVID-19 testing facility in less than two weeks.

We've screened more than 1,275 cancer cell lines as part of the Cancer Dependency Map (DepMap).

Ó³»­´«Ã½ Genomics Platform sequences a whole human genome every four minutes.

More than 11,000 individuals living with cancer in the United States and Canada have partnered with Count Me In to share their experiences and help accelerate cancer research.

The Drug Repurposing Hub is one of the most comprehensive and up-to-date biologically annotated collections of FDA-approved compounds in the world. Researchers anywhere can explore more than 6,000 drugs in the hub and search for possible new uses for them to jump-start new drug discovery.

In 2021, our sustainability efforts sent more than 80 percent of waste from the Genomics Platform to either a recycling facility or to an incineration plant that generates electricity.

Through Ó³»­´«Ã½'s Scientists in the Classroom program, Ó³»­´«Ã½ researchers visit every 8th grade classroom in Cambridge each year to talk about genetics and evolution.

Every summer, 18 high school students spend six weeks at Ó³»­´«Ã½ working side-by-side with mentors on cutting-edge research.

In November 2022, Ó³»­´«Ã½â€™s Genomics Platform sequenced its 500,000th whole human genome, a mere four years after sequencing its 100,000th.

By the end of 2022, Ó³»­´«Ã½â€™s COVID-19 testing lab had processed more than 37 million tests.

Working with Addgene, Ó³»­´«Ã½ has shared CRISPR genome-editing reagents with researchers at more than 3,200 institutions in 76 countries.

The NeuroGAP-Psychosis project, a collaboration between the Stanley Center for Psychiatric Research and Harvard T.H. Chan School of Public Health to study the genetics of severe mental illness, has recruited more than 42,000 participants in Ethiopia, Kenya, Uganda, and South Africa.

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