Jordi J, Guggiana-Nilo D, Bolton AD, et al. High-throughput screening for selective appetite modulators: A multibehavioral and translational drug discovery strategy. Sci Adv. 2018;4(10):eaav1966. doi:10.1126/sciadv.aav1966
Singh G, Dahlin JL, Walters MA. Risk Management in Early Discovery Medicinal Chemistry. Methods Enzymol. 2018;610:1-25. doi:10.1016/bs.mie.2018.09.012
Leifer BS, Doyle SK, Richters A, Evans HL, Koehler AN. An Array-Based Ligand Discovery Platform for Proteins With Short Half-Lives. Methods Enzymol. 2018;610:191-218. doi:10.1016/bs.mie.2018.09.019
Fang C, Lee KK, Nietupski R, et al. Discovery of heterocyclic replacements for the coumarin core of anti-tubercular FadD32 inhibitors. Bioorg Med Chem Lett. 2018;28(22):3529-3533. doi:10.1016/j.bmcl.2018.09.037
Li Y, Wei L, Meinsohn MC, et al. A screen of repurposed drugs identifies AMHR2/MISR2 agonists as potential contraceptives. Proc Natl Acad Sci U S A. 2022;119(15):e2122512119. doi:10.1073/pnas.2122512119
Iyer KR, Camara K, Daniel-Ivad M, et al. An oxindole efflux inhibitor potentiates azoles and impairs virulence in the fungal pathogen Candida auris. Nat Commun. 2020;11(1):6429. doi:10.1038/s41467-020-20183-3
Ferrer M, Kapoor TM, Strassmaier T, et al. Selection of gp41-mediated HIV-1 cell entry inhibitors from biased combinatorial libraries of non-natural binding elements. Nat Struct Biol. 1999;6(10):953-60. doi:10.1038/13324
Marcaurelle LA, Comer E, Dandapani S, et al. An aldol-based build/couple/pair strategy for the synthesis of medium- and large-sized rings: discovery of macrocyclic histone deacetylase inhibitors. J Am Chem Soc. 2010;132(47):16962-76. doi:10.1021/ja105119r
Comer E, Duvall JR, Lee M duPont. Utilizing diversity-oriented synthesis in antimicrobial drug discovery. Future Med Chem. 2014;6(17):1927-42. doi:10.4155/fmc.14.111
Perlstein EO, Ruderfer DM, Roberts DC, Schreiber SL, Kruglyak L. Genetic basis of individual differences in the response to small-molecule drugs in yeast. Nat Genet. 2007;39(4):496-502. doi:10.1038/ng1991